fluorouracil has been researched along with Hyperplasia in 16 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To explore the effect of intralesional injection of low concentration 5-fluorouracil (5-FU) on inhibition of angiogenesis of keloid." | 9.12 | [Clinical study on keloid treatment with intralesional injection of low concentration 5-fluorouracil]. ( Cao, YL; Liu, W; Wu, XL, 2006) |
| "To assess the effect of topical application of 5-fluorouracil (5-FU) on intimal hyperplasia in rabbit vein graft." | 7.75 | [Inhibitory effect of topical application of 5-fluorouracil on intimal hyperplasia of vein graft]. ( Chen, Z; Guo, M; Ma, L; Tian, D; Wu, X; Zhang, Y; Zheng, Z, 2009) |
| "To explore the effect of intralesional injection of low concentration 5-fluorouracil (5-FU) on inhibition of angiogenesis of keloid." | 5.12 | [Clinical study on keloid treatment with intralesional injection of low concentration 5-fluorouracil]. ( Cao, YL; Liu, W; Wu, XL, 2006) |
| "All patients died from neoplastic disease progression despite further chemotherapy at 6, 17 and 31 months following the diagnosis of NRH." | 1.34 | Nodular regenerative hyperplasia: a deleterious consequence of chemotherapy for colorectal liver metastases? ( Canon, JL; Ceratti, A; Gigot, JF; Horsmans, Y; Hubert, C; Humblet, Y; Machiels, JP; Rahier, J; Sempoux, C, 2007) |
| "Only two of them bore colonic cancer." | 1.28 | Disappearance of hyperplastic polyposis after resection of rectal cancer. Report of two cases. ( Fujita, S; Kusunoki, M; Sakanoue, Y; Shoji, Y; Utsunomiya, J; Yamamura, T; Yanagi, H, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (31.25) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calderaro, J | 1 |
| Azoulay, D | 1 |
| Zafrani, ES | 1 |
| Lee, IH | 1 |
| Lee, JE | 1 |
| Byeon, SW | 1 |
| Lee, HJ | 1 |
| Huo, SM | 1 |
| Yoon, SB | 1 |
| Kim, JS | 1 |
| Lee, SH | 1 |
| Roh, SY | 1 |
| Guo, M | 1 |
| Zhang, Y | 1 |
| Tian, D | 1 |
| Wu, X | 1 |
| Chen, Z | 1 |
| Ma, L | 1 |
| Zheng, Z | 1 |
| Miroshnichenko, LA | 1 |
| Shdanov, VV | 1 |
| Zyuz'kov, GN | 1 |
| Simanina, EV | 1 |
| Stavrova, LA | 1 |
| Udut, EV | 1 |
| Khrichkova, TY | 1 |
| Minakova, MY | 1 |
| Goldberg, VE | 1 |
| Dygai, AM | 1 |
| Zawar, V | 1 |
| Kirloskar, M | 1 |
| Chuh, A | 1 |
| Wu, XL | 1 |
| Liu, W | 1 |
| Cao, YL | 1 |
| Hubert, C | 1 |
| Sempoux, C | 1 |
| Horsmans, Y | 1 |
| Rahier, J | 1 |
| Humblet, Y | 1 |
| Machiels, JP | 1 |
| Ceratti, A | 1 |
| Canon, JL | 1 |
| Gigot, JF | 1 |
| Tsuji, T | 1 |
| Nakagawa, K | 1 |
| Hamada, T | 1 |
| Ryan, CJ | 1 |
| Wood, CB | 1 |
| Blumgart, LH | 1 |
| Krunic, AL | 1 |
| Djerdj, K | 1 |
| Starcevic-Bozovic, A | 1 |
| Kozomara, MM | 1 |
| Martinovic, NM | 1 |
| Vesic, SA | 1 |
| Djokic, JH | 1 |
| Loyer, E | 1 |
| David, C | 1 |
| Sella, A | 1 |
| Ellerhorst, J | 1 |
| Fowble, B | 1 |
| Hanlon, AL | 1 |
| Patchefsky, A | 1 |
| Freedman, G | 1 |
| Hoffman, JP | 1 |
| Sigurdson, ER | 1 |
| Goldstein, LJ | 1 |
| Harrison, SD | 1 |
| Denine, EP | 1 |
| Giles, HD | 1 |
| Niimoto, M | 1 |
| Yamagata, S | 1 |
| Toge, T | 1 |
| Harada, T | 1 |
| Ikeda, H | 1 |
| Hattori, T | 1 |
| Kusunoki, M | 1 |
| Fujita, S | 1 |
| Sakanoue, Y | 1 |
| Shoji, Y | 1 |
| Yanagi, H | 1 |
| Yamamura, T | 1 |
| Utsunomiya, J | 1 |
| Westburg, SP | 1 |
| Stone, OJ | 1 |
1 review available for fluorouracil and Hyperplasia
| Article | Year |
|---|---|
Pseudoepitheliomatous, keratotic and micaceous balanitis. Case report and review of the literature.
Topics: Balanitis; Fluorouracil; Follow-Up Studies; Humans; Hyperplasia; Male; Middle Aged | 1996 |
1 trial available for fluorouracil and Hyperplasia
| Article | Year |
|---|---|
[Clinical study on keloid treatment with intralesional injection of low concentration 5-fluorouracil].
Topics: Adrenal Cortex Hormones; Adult; Combined Modality Therapy; Female; Fluorouracil; Humans; Hyperplasia | 2006 |
14 other studies available for fluorouracil and Hyperplasia
| Article | Year |
|---|---|
Hepatocellular carcinoma and nodular regenerative hyperplasia after chemotherapy for metastatic colorectal carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Colorectal Neoplasms; Drug Therapy; Fluorouracil; | 2014 |
[A Case of Advanced Gastric Cancer Presenting as Multiple Colonic Lymphoid Hyperplasia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colonoscopy; Female; Fluorouracil | 2015 |
[Inhibitory effect of topical application of 5-fluorouracil on intimal hyperplasia of vein graft].
Topics: Animals; Fluorouracil; Hyperplasia; Male; Rabbits; Tunica Intima; Veins | 2009 |
Mechanisms of hemostimulating effects of granulocytic CSF and pantohematogen under conditions of cytostatic myelosuppression.
Topics: Animals; Biological Factors; Bone Marrow; Bone Marrow Cells; Cyclophosphamide; Female; Fluorouracil; | 2011 |
'Watering-can penis' in pseudoepitheliomatous, keratotic and micaceous balanitis.
Topics: Administration, Topical; Balanitis; Biopsy, Needle; Carcinoma, Verrucous; Diagnosis, Differential; F | 2004 |
Nodular regenerative hyperplasia: a deleterious consequence of chemotherapy for colorectal liver metastases?
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Chemot | 2007 |
Different effects of topically applied 5-fluorouracil on hairy and hairless mice.
Topics: Animals; Dihydroxyphenylalanine; Fluorouracil; Hyperplasia; Hypertrophy; Melanocytes; Mice; Mice, Ha | 1984 |
The effect of 5-fluorouracil on DNA synthesis in the rat liver undergoing compensatory hyperplasia after partial hepatectomy.
Topics: Animals; DNA; Fluorouracil; Hepatectomy; Hyperplasia; Liver; Liver Regeneration; Male; Organ Size; R | 1983 |
Hyperplasia of axillary nodes in patients undergoing immunotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Axilla; Carcinoma, Renal Cell; Fluorouracil; Humans; | 1997 |
The presence of proliferative breast disease with atypia does not significantly influence outcome in early-stage invasive breast cancer treated with conservative surgery and radiation.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neopl | 1998 |
Evidence for toxicologic activity of ftorafur independent of conversion to 5-fluorouracil.
Topics: Animals; Digestive System; Fluorouracil; Hyperplasia; Intestinal Mucosa; Male; Mice; Tegafur | 1979 |
Evaluation of chemotherapeutic effects on gastric cancer in relation to the histological pattern.
Topics: Adenocarcinoma; Adenocarcinoma, Papillary; Cytarabine; Drug Therapy, Combination; Fluorouracil; Huma | 1978 |
Disappearance of hyperplastic polyposis after resection of rectal cancer. Report of two cases.
Topics: Adenocarcinoma; Aged; Anastomosis, Surgical; Brachytherapy; Colonic Neoplasms; Colonoscopy; Combined | 1991 |
Multiple cutaneous squamous cell carcinomas during immunosuppressive therapy.
Topics: Adult; Azathioprine; Carcinoma, Squamous Cell; Fluorouracil; Humans; Hyperplasia; Immunosuppressive | 1973 |