Page last updated: 2024-10-27

fluorouracil and Hyperinsulinism

fluorouracil has been researched along with Hyperinsulinism in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Hyperinsulinism: A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hickish, T1
Astras, G1
Thomas, P1
Penfold, S1
Purandare, L1
Hickish, TF1
Kerr, D1
Hinchliffe, E1
Allcock, RL1
Mansoor, W1
Myers, MA1

Other Studies

2 other studies available for fluorouracil and Hyperinsulinism

ArticleYear
Glucose intolerance during adjuvant chemotherapy for breast cancer.
    Journal of the National Cancer Institute, 2009, Apr-01, Volume: 101, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Glucose; Breast Neoplasms; Chemot

2009
A patient with a metastatic gastroenteropancreatic endocrine carcinoma causing hyperinsulinaemic hypoglycaemia and the carcinoid syndrome.
    Annals of clinical biochemistry, 2011, Volume: 48, Issue:Pt 6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma; Fl

2011