fluorouracil has been researched along with Hot Flashes in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Hot Flashes: A sudden, temporary sensation of heat predominantly experienced by some women during MENOPAUSE. (Random House Unabridged Dictionary, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated QOL data from 874 pre- and perimenopausal women with lymph node-negative breast cancer who were randomly assigned to receive six courses of classical cyclophosphamide, methotrexate, and fluorouracil (CMF) chemotherapy, ovarian suppression with goserelin for 24 months, or six courses of classical CMF followed by 18 months of goserelin." | 9.12 | Adjuvant chemotherapy followed by goserelin compared with either modality alone: the impact on amenorrhea, hot flashes, and quality of life in premenopausal patients--the International Breast Cancer Study Group Trial VIII. ( Aebi, S; Bernhard, J; Castiglione-Gertsch, M; Coates, AS; Collins, J; Forbes, JF; Gelber, RD; Goldhirsch, A; Hürny, C; Murray, E; Price, KN; Thürlimann, B; Zahrieh, D, 2007) |
| "We evaluated QOL data from 874 pre- and perimenopausal women with lymph node-negative breast cancer who were randomly assigned to receive six courses of classical cyclophosphamide, methotrexate, and fluorouracil (CMF) chemotherapy, ovarian suppression with goserelin for 24 months, or six courses of classical CMF followed by 18 months of goserelin." | 5.12 | Adjuvant chemotherapy followed by goserelin compared with either modality alone: the impact on amenorrhea, hot flashes, and quality of life in premenopausal patients--the International Breast Cancer Study Group Trial VIII. ( Aebi, S; Bernhard, J; Castiglione-Gertsch, M; Coates, AS; Collins, J; Forbes, JF; Gelber, RD; Goldhirsch, A; Hürny, C; Murray, E; Price, KN; Thürlimann, B; Zahrieh, D, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bernhard, J | 1 |
| Zahrieh, D | 1 |
| Castiglione-Gertsch, M | 1 |
| Hürny, C | 1 |
| Gelber, RD | 1 |
| Forbes, JF | 1 |
| Murray, E | 1 |
| Collins, J | 1 |
| Aebi, S | 1 |
| Thürlimann, B | 1 |
| Price, KN | 1 |
| Goldhirsch, A | 1 |
| Coates, AS | 1 |
1 trial available for fluorouracil and Hot Flashes
| Article | Year |
|---|---|
Adjuvant chemotherapy followed by goserelin compared with either modality alone: the impact on amenorrhea, hot flashes, and quality of life in premenopausal patients--the International Breast Cancer Study Group Trial VIII.
Topics: Adult; Age Factors; Amenorrhea; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherap | 2007 |