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fluorouracil and Herpes Simplex Virus Infection

fluorouracil has been researched along with Herpes Simplex Virus Infection in 4 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
" We evaluated the effects of these adenoviruses with 5-fluorouracil (5-FU) and/or ganciclovir (GCV) on human cholangiocarcinoma cells (HuCCT1, with mutant p53) in vitro and in vivo."3.75Oncolytic gene therapy combined with double suicide genes for human bile duct cancer in nude mouse models. ( Hamada, H; Honda, K; Kobayashi, N; Kojima, Y, 2009)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kojima, Y1
Honda, K1
Hamada, H1
Kobayashi, N1
García-Montesinos-De la Peña, M1
Oteiza-López, L1
Aldunate-Calvo, S1
Gómez-Sánchez, MJ1
Sáenz-Bañuelos, JJ1
Tihista-Jiménez, JA1
Rees, RB1
Hanna, C1

Reviews

1 review available for fluorouracil and Herpes Simplex Virus Infection

ArticleYear
Current dermatologic therapy.
    Cutis, 1976, Volume: 18, Issue:4

    Topics: Acne Vulgaris; Administration, Topical; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antifungal A

1976

Other Studies

3 other studies available for fluorouracil and Herpes Simplex Virus Infection

ArticleYear
Oncolytic gene therapy combined with double suicide genes for human bile duct cancer in nude mouse models.
    The Journal of surgical research, 2009, Volume: 157, Issue:1

    Topics: Adenoviridae; Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Bile Duct Neoplasms; Bile

2009
[Herpes simplex virus bronchopneumonitis in patient with acute respiratory failure after surgery].
    Medicina intensiva, 2010, Volume: 34, Issue:2

    Topics: Acute Disease; Acyclovir; Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antiviral Agents; B

2010
Incorporation of idoxuridine analogs into corneal herpes simplex virus.
    Annals of ophthalmology, 1972, Volume: 4, Issue:11

    Topics: Animals; Autoradiography; Bromodeoxyuridine; Cornea; DNA, Viral; Epithelium; Floxuridine; Fluorourac

1972
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