fluorouracil and Herpes Simplex Virus Infection
fluorouracil has been researched along with Herpes Simplex Virus Infection in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
" We evaluated the effects of these adenoviruses with 5-fluorouracil (5-FU) and/or ganciclovir (GCV) on human cholangiocarcinoma cells (HuCCT1, with mutant p53) in vitro and in vivo." | 3.75 | Oncolytic gene therapy combined with double suicide genes for human bile duct cancer in nude mouse models. ( Hamada, H; Honda, K; Kobayashi, N; Kojima, Y, 2009) |
Research
Studies (4)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (50.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (25.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Kojima, Y | 1 |
Honda, K | 1 |
Hamada, H | 1 |
Kobayashi, N | 1 |
García-Montesinos-De la Peña, M | 1 |
Oteiza-López, L | 1 |
Aldunate-Calvo, S | 1 |
Gómez-Sánchez, MJ | 1 |
Sáenz-Bañuelos, JJ | 1 |
Tihista-Jiménez, JA | 1 |
Rees, RB | 1 |
Hanna, C | 1 |
Reviews
1 review available for fluorouracil and Herpes Simplex Virus Infection
Article | Year |
---|---|
Current dermatologic therapy.
Topics: Acne Vulgaris; Administration, Topical; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antifungal A | 1976 |
Other Studies
3 other studies available for fluorouracil and Herpes Simplex Virus Infection
Article | Year |
---|---|
Oncolytic gene therapy combined with double suicide genes for human bile duct cancer in nude mouse models.
Topics: Adenoviridae; Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Bile Duct Neoplasms; Bile | 2009 |
[Herpes simplex virus bronchopneumonitis in patient with acute respiratory failure after surgery].
Topics: Acute Disease; Acyclovir; Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antiviral Agents; B | 2010 |
Incorporation of idoxuridine analogs into corneal herpes simplex virus.
Topics: Animals; Autoradiography; Bromodeoxyuridine; Cornea; DNA, Viral; Epithelium; Floxuridine; Fluorourac | 1972 |