Page last updated: 2024-10-27

fluorouracil and Hemolysis

fluorouracil has been researched along with Hemolysis in 40 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.

Research Excerpts

ExcerptRelevanceReference
" Herein, highly uniform and stable selenium nanoparticles with epidermal growth factor receptor (EGFR) targeting and tumor microenvironment-responsive ability (Se-5Fu-Gd-P(Cet/YI-12)) were designed and synthesized by using EGFR as the targeting molecule, gadolinium chelate as the magnetic resonance imaging contrast agent, 5-fluorouracil (5Fu) and cetuximab as drug payloads, polyamidoamine (PAMAM) and 3,3'-dithiobis (sulfosuccinimidyl propionate) as the response agents of intratumoral glutathione, and pH for the treatment and diagnosis of nasopharyngeal carcinoma (NPC)."7.91Highly Uniform Synthesis of Selenium Nanoparticles with EGFR Targeting and Tumor Microenvironment-Responsive Ability for Simultaneous Diagnosis and Therapy of Nasopharyngeal Carcinoma. ( Chen, T; Huang, J; Huang, W; Lin, H; Lin, X; Peng, L; Zhang, Z, 2019)
"5-FU/Megestrol acetate loaded fibrinogen-graft-PNIPAAm Nanogels (5-FU/Meg-fib-graft-PNIPAAm NGs) were prepared for thermo responsive drug delivery toward α5β1-integrins expressing breast cancer cells in vitro (MCF-7 cells)."7.80Dual drug encapsulated thermo-sensitive fibrinogen-graft-poly (N-isopropyl acrylamide) nanogels for breast cancer therapy. ( Baby, T; Chennazhi, KP; Jayakumar, R; Rejinold, NS, 2014)
" Herein, highly uniform and stable selenium nanoparticles with epidermal growth factor receptor (EGFR) targeting and tumor microenvironment-responsive ability (Se-5Fu-Gd-P(Cet/YI-12)) were designed and synthesized by using EGFR as the targeting molecule, gadolinium chelate as the magnetic resonance imaging contrast agent, 5-fluorouracil (5Fu) and cetuximab as drug payloads, polyamidoamine (PAMAM) and 3,3'-dithiobis (sulfosuccinimidyl propionate) as the response agents of intratumoral glutathione, and pH for the treatment and diagnosis of nasopharyngeal carcinoma (NPC)."3.91Highly Uniform Synthesis of Selenium Nanoparticles with EGFR Targeting and Tumor Microenvironment-Responsive Ability for Simultaneous Diagnosis and Therapy of Nasopharyngeal Carcinoma. ( Chen, T; Huang, J; Huang, W; Lin, H; Lin, X; Peng, L; Zhang, Z, 2019)
"5-FU/Megestrol acetate loaded fibrinogen-graft-PNIPAAm Nanogels (5-FU/Meg-fib-graft-PNIPAAm NGs) were prepared for thermo responsive drug delivery toward α5β1-integrins expressing breast cancer cells in vitro (MCF-7 cells)."3.80Dual drug encapsulated thermo-sensitive fibrinogen-graft-poly (N-isopropyl acrylamide) nanogels for breast cancer therapy. ( Baby, T; Chennazhi, KP; Jayakumar, R; Rejinold, NS, 2014)
"In Kit(Y567F/Y567F) mice, steady-state erythropoiesis was unperturbed while recovery from anemia due to 5-fluorouracil or phenylhydrazine was markedly impaired."3.75A KIT juxtamembrane PY567 -directed pathway provides nonredundant signals for erythroid progenitor cell development and stress erythropoiesis. ( Agosti, V; Besmer, P; Karur, V; Sathyanarayana, P; Wojchowski, DM, 2009)
"In most cases, hyperbilirubinemia was associated with concomitant alterations in other hemolytic parameters."2.71Fluoropyrimidine therapy: hyperbilirubinemia as a consequence of hemolysis. ( Cassidy, J; Filipovic-Ljeskovic, I; Jelic, S; Nikolic-Tomasevic, Z; Tomasevic, Z, 2005)
" In addition, the in vivo pharmacokinetic data in mouse model revealed the improved plasma concentrations of 5-FU and CUR which prolonged up to 72 h unlike the bare drugs."1.40In vitro combinatorial anticancer effects of 5-fluorouracil and curcumin loaded N,O-carboxymethyl chitosan nanoparticles toward colon cancer and in vivo pharmacokinetic studies. ( Anitha, A; Chennazhi, KP; Jayakumar, R; Lakshmanan, VK; Sreeranganathan, M, 2014)
"We report two cases of colorectal cancer whose serum iron level demonstrated recurrent elevation after chemotherapy."1.36[Two cases of colorectal cancer presenting with periodic, transient elevation of serum iron due to hemolysis after chemotherapy including 5-FU]. ( Furuse, J; Hosokawa, Y; Itabashi, M; Iwamoto, N; Kase, Y; Kitagawa, N; Miyazawa, T; Motoori, S; Saisho, H, 2010)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.00)18.7374
1990's3 (7.50)18.2507
2000's5 (12.50)29.6817
2010's25 (62.50)24.3611
2020's5 (12.50)2.80

Authors

AuthorsStudies
Ayyad, SE1
Makki, MS1
Al-Kayal, NS1
Basaif, SA1
El-Foty, KO1
Asiri, AM1
Alarif, WM1
Badria, FA2
Abdel-Wahab, BF1
Awad, GE1
Deng, X1
Qiu, Q1
Yang, B1
Wang, X1
Huang, W3
Qian, H1
Ahmed, MM1
Ameen, MSM1
Abazari, M1
Badeleh, SM1
Rostamizadeh, K1
Mohammed, SS1
Wang, F1
Zhang, Q1
Huang, K1
Li, J1
Wang, K1
Zhang, K1
Tang, X1
Kumar, B2
Priyadarshi, R1
Deeba, F2
Kulshreshtha, A2
Kumar, A1
Agrawal, G1
Gopinath, P2
Negi, YS2
Zhou, S1
Ding, C1
Wang, C1
Fu, J1
Cao, J1
Huang, J2
Gui, S1
Chu, X1
Sahu, P1
Kashaw, SK1
Jain, S2
Sau, S1
Iyer, AK1
Reneeta, NP1
Thiyonila, B1
Aathmanathan, VS1
Ramya, T1
Chandrasekar, P1
Subramanian, N1
Prajapati, VK1
Krishnan, M1
Moghimipour, E1
Rezaei, M1
Kouchak, M1
Ramezani, Z1
Amini, M1
Ahmadi Angali, K1
Saremy, S1
Abedin Dorkoosh, F1
Handali, S1
Kumar, V1
Bano, S1
Ashjaran, M1
Babazadeh, M1
Akbarzadeh, A1
Davaran, S1
Salehi, R1
Ning, Q2
Liu, YF1
Ye, PJ2
Gao, P2
Li, ZP2
Tang, SY1
He, DX2
Tang, SS1
Wei, H1
Yu, CY2
Zhang, Z1
Lin, X1
Lin, H1
Peng, L1
Chen, T1
Nejadshafiee, V1
Naeimi, H1
Goliaei, B1
Bigdeli, B1
Sadighi, A1
Dehghani, S1
Lotfabadi, A1
Hosseini, M1
Nezamtaheri, MS1
Amanlou, M1
Sharifzadeh, M1
Khoobi, M1
Tabata, A1
Ohkubo, Y1
Tamura, M1
Tomoyasu, T1
Ohkura, K1
Nagamune, H1
Rejinold, NS1
Baby, T1
Chennazhi, KP3
Jayakumar, R3
Tavano, L1
Aiello, R1
Ioele, G1
Picci, N1
Muzzalupo, R1
Anitha, A2
Sreeranganathan, M1
Lakshmanan, VK1
Salama, A1
Mayer, B1
Jain, T1
Kumar, S1
Dutta, PK1
Garg, A1
Rai, G1
Lodhi, S1
Jain, AP1
Yadav, AK1
Alupei, L1
Peptu, CA1
Lungan, AM1
Desbrieres, J1
Chiscan, O1
Radji, S1
Popa, M1
Huang, C1
Li, NM1
Yang, S1
Xiang, L1
Tan, XW1
Singh, P1
Gupta, U1
Asthana, A1
Jain, NK2
Agosti, V1
Karur, V1
Sathyanarayana, P1
Besmer, P1
Wojchowski, DM1
Ulusakarya, A1
Misra, S1
Haydar, M1
Habert, H1
Castagne, V1
Gumus, Y1
Delmas-Marsalet, B1
Machover, D1
Magalhães, HI1
Bezerra, DP1
Cavalcanti, BC1
Wilke, DV1
Rotta, R1
de Lima, DP1
Beatriz, A1
Alves, AP1
Bitencourt, Fda S1
de Figueiredo, IS1
Alencar, NM1
Costa-Lotufo, LV1
Moraes, MO1
Pessoa, C1
Hosokawa, Y1
Motoori, S1
Miyazawa, T1
Iwamoto, N1
Kase, Y1
Kitagawa, N1
Saisho, H1
Furuse, J1
Itabashi, M1
Nair, SV1
Banerjee, S1
Sen, K1
Pal, TK1
Guha, SK1
Bhadra, D1
Bhadra, S1
INGRAHAM, JS1
BUSSARD, A1
Nikolic-Tomasevic, Z1
Jelic, S1
Cassidy, J1
Filipovic-Ljeskovic, I1
Tomasevic, Z1
Canti, G1
Franco, P1
Marelli, O1
Ricci, L1
Nicolin, A1
Itoh, H1
Ito, H1
Amano, H1
Noda, H1
Nandurkar, HH1
Robb, L1
Tarlinton, D1
Barnett, L1
Köntgen, F1
Begley, CG1
Blot, E1
Marie, I1
Delastre, O1
Cailleux, N1
Pouillart, P1
Lévesque, H1
Courtois, H1
Sørbye, H1
Bruserud, Y1
Dahl, O1

Trials

1 trial available for fluorouracil and Hemolysis

ArticleYear
Fluoropyrimidine therapy: hyperbilirubinemia as a consequence of hemolysis.
    Cancer chemotherapy and pharmacology, 2005, Volume: 56, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P

2005

Other Studies

39 other studies available for fluorouracil and Hemolysis

ArticleYear
Cytotoxic and protective DNA damage of three new diterpenoids from the brown alga Dictoyota dichotoma.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Animals; Antineoplastic Agents; Antioxidants; Benzothiazoles; Cell Line, Tumor; Cell Survival; Chlor

2011
Synthesis, antimicrobial, antioxidant, anti-hemolytic and cytotoxic evaluation of new imidazole-based heterocycles.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antioxidants; Bacteria; Cell Proliferation; D

2011
Design, synthesis and biological evaluation of novel peptides with anti-cancer and drug resistance-reversing activities.
    European journal of medicinal chemistry, 2015, Jan-07, Volume: 89

    Topics: Animals; Antineoplastic Agents; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug;

2015
Chitosan-decorated and tripolyphosphate-crosslinked pH-sensitive niosomal nanogels for Controlled release of fluoropyrimidine 5-fluorouracil.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 164

    Topics: Animals; Antimetabolites; Chitosan; Delayed-Action Preparations; Drug Carriers; Fluorouracil; Hemoly

2023
Preparation and characterization of carboxymethyl cellulose containing quaternized chitosan for potential drug carrier.
    International journal of biological macromolecules, 2020, Jul-01, Volume: 154

    Topics: Anti-Bacterial Agents; Apoptosis; Bandages; Carboxymethylcellulose Sodium; Chitosan; Drug Carriers;

2020
Redox responsive xylan-SS-curcumin prodrug nanoparticles for dual drug delivery in cancer therapy.
    Materials science & engineering. C, Materials for biological applications, 2020, Volume: 107

    Topics: Antineoplastic Combined Chemotherapy Protocols; Curcumin; Disulfides; Drug Delivery Systems; Drug Li

2020
UV-light cross-linked and pH de-cross-linked coumarin-decorated cationic copolymer grafted mesoporous silica nanoparticles for drug and gene co-delivery in vitro.
    Materials science & engineering. C, Materials for biological applications, 2020, Volume: 108

    Topics: Animals; Biocompatible Materials; Cations; Chlorocebus aethiops; COS Cells; Coumarins; Cross-Linking

2020
Preparation, Synergism, and Biocompatibility of in situ Liquid Crystals Loaded with Sinomenine and 5-Fluorouracil for Treatment of Liver Cancer.
    International journal of nanomedicine, 2021, Volume: 16

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Death; Drug Carriers; Drug Liberatio

2021
Assessment of penetration potential of pH responsive double walled biodegradable nanogels coated with eucalyptus oil for the controlled delivery of 5-fluorouracil: In vitro and ex vivo studies.
    Journal of controlled release : official journal of the Controlled Release Society, 2017, 05-10, Volume: 253

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line; Cell Survival; Chitosan; Delayed-Act

2017
Encapsulation and Systemic Delivery of 5-Fluorouracil Conjugated with Silkworm Pupa Derived Protein Nanoparticles for Experimental Lymphoma Cancer.
    Bioconjugate chemistry, 2018, 09-19, Volume: 29, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Biocompatible Materials; Bombyx; Cell Line, Tumor; Cell Pr

2018
A mechanistic study of the effect of transferrin conjugation on cytotoxicity of targeted liposomes.
    Journal of microencapsulation, 2018, Volume: 35, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Cell Survival; Cytochromes c;

2018
Lipophilic 5-fluorouracil prodrug encapsulated xylan-stearic acid conjugates nanoparticles for colon cancer therapy.
    International journal of biological macromolecules, 2019, May-01, Volume: 128

    Topics: Animals; Cell Line, Tumor; Cell Survival; Chemical Phenomena; Colonic Neoplasms; Disease Models, Ani

2019
Stimuli-responsive polyvinylpyrrolidone-NIPPAm-lysine graphene oxide nano-hybrid as an anticancer drug delivery on MCF7 cell line.
    Artificial cells, nanomedicine, and biotechnology, 2019, Volume: 47, Issue:1

    Topics: Acrylamides; bcl-2-Associated X Protein; Drug Carriers; Drug Liberation; Fluorouracil; Gene Expressi

2019
Delivery of Liver-Specific miRNA-122 Using a Targeted Macromolecular Prodrug toward Synergistic Therapy for Hepatocellular Carcinoma.
    ACS applied materials & interfaces, 2019, Mar-20, Volume: 11, Issue:11

    Topics: ADAM17 Protein; Animals; Apoptosis; Biocompatible Materials; Carcinoma, Hepatocellular; Cell Line; C

2019
Highly Uniform Synthesis of Selenium Nanoparticles with EGFR Targeting and Tumor Microenvironment-Responsive Ability for Simultaneous Diagnosis and Therapy of Nasopharyngeal Carcinoma.
    ACS applied materials & interfaces, 2019, Mar-27, Volume: 11, Issue:12

    Topics: Cell Line, Tumor; Cell Movement; Cetuximab; Contrast Media; Drug Carriers; ErbB Receptors; Fluoroura

2019
Magnetic bio-metal-organic framework nanocomposites decorated with folic acid conjugated chitosan as a promising biocompatible targeted theranostic system for cancer treatment.
    Materials science & engineering. C, Materials for biological applications, 2019, Volume: 99

    Topics: Animals; Biocompatible Materials; Cell Death; Cell Line, Tumor; Cell Survival; Chitosan; Curcumin; D

2019
Construction of an improved drug delivery system tool with enhanced versatility in cell-targeting.
    Anticancer research, 2013, Volume: 33, Issue:7

    Topics: Carcinoembryonic Antigen; Cell Membrane; Cells, Cultured; Cholesterol; Drug Delivery Systems; Fibrob

2013
Dual drug encapsulated thermo-sensitive fibrinogen-graft-poly (N-isopropyl acrylamide) nanogels for breast cancer therapy.
    Colloids and surfaces. B, Biointerfaces, 2014, Feb-01, Volume: 114

    Topics: Acrylic Resins; Animals; Apoptosis; Breast Neoplasms; Cattle; Drug Delivery Systems; Female; Fibrino

2014
Niosomes from glucuronic acid-based surfactant as new carriers for cancer therapy: preparation, characterization and biological properties.
    Colloids and surfaces. B, Biointerfaces, 2014, Jun-01, Volume: 118

    Topics: Antineoplastic Agents; Doxorubicin; Drug Carriers; Fluorouracil; Glucuronic Acid; Hemolysis; Humans;

2014
In vitro combinatorial anticancer effects of 5-fluorouracil and curcumin loaded N,O-carboxymethyl chitosan nanoparticles toward colon cancer and in vivo pharmacokinetic studies.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2014, Volume: 88, Issue:1

    Topics: Animals; Antineoplastic Agents; Area Under Curve; Blood Coagulation; Cell Cycle; Cell Line; Cell Lin

2014
Diagnostic pitfalls of drug-induced immune hemolytic anemia.
    Immunohematology, 2014, Volume: 30, Issue:2

    Topics: Aged; Anemia, Hemolytic, Autoimmune; Antigen-Antibody Complex; Antihypertensive Agents; Antimetaboli

2014
Dibutyrylchitin nanoparticles as novel drug carrier.
    International journal of biological macromolecules, 2016, Volume: 82

    Topics: Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Survival; Cells, Cult

2016
Hyaluronic acid embedded cellulose acetate phthlate core/shell nanoparticulate carrier of 5-fluorouracil.
    International journal of biological macromolecules, 2016, Volume: 87

    Topics: Adipates; Animals; Cell Line, Tumor; Cellulose; Drug Carriers; Drug Liberation; Fluorouracil; Hemoly

2016
New hybrid magnetic nanoparticles based on chitosan-maltose derivative for antitumor drug delivery.
    International journal of biological macromolecules, 2016, Volume: 92

    Topics: Animals; Antineoplastic Agents; Cell Death; Cell Survival; Chitosan; Drug Delivery Systems; Fluorour

2016
In vitro and in vivo evaluation of macromolecular prodrug GC-FUA based nanoparticle for hepatocellular carcinoma chemotherapy.
    Drug delivery, 2017, Volume: 24, Issue:1

    Topics: A549 Cells; Absorption, Physiological; Animals; Antimetabolites, Antineoplastic; Carcinoma, Hepatoce

2017
Folate and folate-PEG-PAMAM dendrimers: synthesis, characterization, and targeted anticancer drug delivery potential in tumor bearing mice.
    Bioconjugate chemistry, 2008, Nov-19, Volume: 19, Issue:11

    Topics: Animals; Antineoplastic Agents; Dendrimers; Drug Carriers; Female; Fluorouracil; Folic Acid; Hemolys

2008
A KIT juxtamembrane PY567 -directed pathway provides nonredundant signals for erythroid progenitor cell development and stress erythropoiesis.
    Experimental hematology, 2009, Volume: 37, Issue:2

    Topics: Amino Acid Substitution; Anemia; Animals; Antimetabolites, Antineoplastic; Erythroid Precursor Cells

2009
Acute renal failure related to oxaliplatin-induced intravascular hemolysis.
    Medical oncology (Northwood, London, England), 2010, Volume: 27, Issue:4

    Topics: Acute Kidney Injury; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combi

2010
In vitro and in vivo antitumor effects of (4-methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone.
    Cancer chemotherapy and pharmacology, 2011, Volume: 68, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Antimitotic Agents; Antineoplastic Agents; Benzophenones;

2011
[Two cases of colorectal cancer presenting with periodic, transient elevation of serum iron due to hemolysis after chemotherapy including 5-FU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:9

    Topics: Aged; Bilirubin; Colonic Neoplasms; Female; Fluorouracil; Hemolysis; Humans; Iron; Male; Middle Aged

2010
5-flourouracil loaded N,O-carboxymethyl chitosan nanoparticles as an anticancer nanomedicine for breast cancer.
    Journal of biomedical nanotechnology, 2012, Volume: 8, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Blood Coagulation Tests; Breast Neoplasms; Casp

2012
Poly(styrene-co-maleic acid)-based pH-sensitive liposomes mediate cytosolic delivery of drugs for enhanced cancer chemotherapy.
    International journal of pharmaceutics, 2012, Oct-15, Volume: 436, Issue:1-2

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Cycle; Cell Proliferation; Cell Survival; Cells, Cult

2012
A PEGylated dendritic nanoparticulate carrier of fluorouracil.
    International journal of pharmaceutics, 2003, May-12, Volume: 257, Issue:1-2

    Topics: Animals; Antimetabolites, Antineoplastic; Chemistry, Pharmaceutical; Drug Carriers; Drug Stability;

2003
APPLICATION OF A LOCALIZED HEMOLYSIN REACTION FOR SPECIFIC DETECTION OF INDIVIDUAL ANTIBODY-FORMING CELLS.
    The Journal of experimental medicine, 1964, Apr-01, Volume: 119

    Topics: Alcohols; Animals; Antibodies; Antibody Formation; Antigen-Antibody Reactions; Antimetabolites; Comp

1964
Hematoporphyrin derivative rescue from toxicity caused by chemotherapy or radiation in a murine leukemia model (L1210).
    Cancer research, 1984, Volume: 44, Issue:4

    Topics: Animals; Antibody Formation; Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Hemagglutination

1984
Inhibitory action of a (1-->6)-beta-D-glucan-protein complex (F III-2-b) isolated from Agaricus blazei Murill ("himematsutake") on Meth A fibrosarcoma-bearing mice and its antitumor mechanism.
    Japanese journal of pharmacology, 1994, Volume: 66, Issue:2

    Topics: Agaricus; Animals; Antineoplastic Agents; Disease Models, Animal; Drug Synergism; Erythrocytes; Fema

1994
Adult mice with targeted mutation of the interleukin-11 receptor (IL11Ra) display normal hematopoiesis.
    Blood, 1997, Sep-15, Volume: 90, Issue:6

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Fluorouracil;

1997
[Thrombotic microangiopathy associated with cancer is an oncologic emergency: a case report].
    La Revue de medecine interne, 1999, Volume: 20, Issue:5

    Topics: Adenocarcinoma; Adult; Anticoagulants; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Ch

1999
Oxaliplatin-induced haematological emergency with an immediate severe thrombocytopenia and haemolysis.
    Acta oncologica (Stockholm, Sweden), 2001, Volume: 40, Issue:7

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Colonic Ne

2001
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