fluorouracil has been researched along with Hemoglobinuria, Paroxysmal in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Hemoglobinuria, Paroxysmal: A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, M | 1 |
| Chase, J | 1 |
| Brinkmeier, M | 1 |
| Xu, J | 1 |
| Weinberg, DN | 1 |
| Schira, J | 1 |
| Friedman, A | 1 |
| Malek, S | 1 |
| Grembecka, J | 1 |
| Cierpicki, T | 1 |
| Dou, Y | 1 |
| Camper, SA | 1 |
| Maillard, I | 1 |
1 other study available for fluorouracil and Hemoglobinuria, Paroxysmal
| Article | Year |
|---|---|
Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells.
Topics: Anemia, Aplastic; Animals; Animals, Newborn; Bone Marrow Diseases; Bone Marrow Failure Disorders; Bo | 2015 |