Page last updated: 2024-10-27

fluorouracil and Hematoma

fluorouracil has been researched along with Hematoma in 8 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Hematoma: A collection of blood outside the BLOOD VESSELS. Hematoma can be localized in an organ, space, or tissue.

Research Excerpts

ExcerptRelevanceReference
"We reported two cases of retroperitoneal hematoma in patients who received a combination of anticoagulant therapy and 5-fluorouracil (5-FU)."7.73Two cases of retroperitoneal hematoma caused by combination of anticoagulant therapy and 5-fluorouracil. ( Furutani, K; Furutani, S; Kashihara, K; Minato, M; Morita, N; Murase, T; Nishitani, H; Otsuka, H; Tagashira, H; Tsujikawa, T; Yoneda, K, 2005)
"We reported two cases of retroperitoneal hematoma in patients who received a combination of anticoagulant therapy and 5-fluorouracil (5-FU)."3.73Two cases of retroperitoneal hematoma caused by combination of anticoagulant therapy and 5-fluorouracil. ( Furutani, K; Furutani, S; Kashihara, K; Minato, M; Morita, N; Murase, T; Nishitani, H; Otsuka, H; Tagashira, H; Tsujikawa, T; Yoneda, K, 2005)
"Patients with stage IV colorectal cancer and peritoneal carcinomatosis are increasingly treated with curative intent and perioperative systemic chemotherapy combined with targeted therapy."1.40Bevacizumab doubles the early postoperative complication rate after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal carcinomatosis of colorectal origin. ( Elias, D; Eveno, C; Gayat, E; Glehen, O; Goéré, D; Passot, G; Pocard, M; Soyer, P, 2014)
"A 59-years-old woman with metastatic rectal cancer treated with bevacizumab, who developed low back pain after 11 cycles of chemotherapy."1.38Perirenal hematoma associated with bevacizumab treatment. ( Hayashi, H; Nakagawa, K; Okamoto, I, 2012)
"Moreover, circulating tumor cells were demonstrated by flow cytometry."1.38[Severe hemorrhage in a patient with metastatic colorectal cancer - case 8/2012]. ( Horger, M; Jaschonek, K; Kanz, L; Kopp, HG; Kurth, R; Mayer, F; Orgel, M, 2012)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Smolenschi, C1
Tazdait, M1
Kuhn, E1
Boige, V1
Eveno, C1
Passot, G1
Goéré, D1
Soyer, P1
Gayat, E1
Glehen, O1
Elias, D1
Pocard, M1
Dominici, LS1
Kuerer, HM1
Babiera, G1
Hahn, KM1
Perkins, G1
Middleton, L1
Ramirez, MM1
Yang, W1
Hortobagyi, GN1
Theriault, RL1
Litton, JK1
Hayashi, H1
Okamoto, I1
Nakagawa, K1
Orgel, M1
Horger, M1
Kurth, R1
Kanz, L1
Jaschonek, K1
Mayer, F1
Kopp, HG1
Morita, N1
Kashihara, K1
Tagashira, H1
Otsuka, H1
Yoneda, K1
Murase, T1
Tsujikawa, T1
Furutani, S1
Furutani, K1
Minato, M1
Nishitani, H1
Antonovic, R1
Rösch, J1
Dotter, CT1
Cohn, I1

Trials

1 trial available for fluorouracil and Hematoma

ArticleYear
Complications and toxic manifestations of surgical adjuvant chemotherapy for breast cancer.
    Surgery, gynecology & obstetrics, 1968, Volume: 127, Issue:6

    Topics: Adult; Aged; Blood Cell Count; Blood Platelets; Blood Transfusion; Breast Neoplasms; Clinical Trials

1968

Other Studies

7 other studies available for fluorouracil and Hematoma

ArticleYear
Bilateral adrenal haematoma complicated by adrenal insufficiency in a patient treated with bevacizumab.
    BMJ case reports, 2021, Feb-22, Volume: 14, Issue:2

    Topics: Adrenal Insufficiency; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neopl

2021
Bevacizumab doubles the early postoperative complication rate after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal carcinomatosis of colorectal origin.
    Annals of surgical oncology, 2014, Volume: 21, Issue:6

    Topics: Abdominal Abscess; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combin

2014
Wound complications from surgery in pregnancy-associated breast cancer (PABC).
    Breast disease, 2010, Volume: 31, Issue:1

    Topics: Abscess; Adult; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Diseases; Breast Neop

2010
Perirenal hematoma associated with bevacizumab treatment.
    Investigational new drugs, 2012, Volume: 30, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Pro

2012
[Severe hemorrhage in a patient with metastatic colorectal cancer - case 8/2012].
    Deutsche medizinische Wochenschrift (1946), 2012, Volume: 137, Issue:34-35

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap

2012
Two cases of retroperitoneal hematoma caused by combination of anticoagulant therapy and 5-fluorouracil.
    The journal of medical investigation : JMI, 2005, Volume: 52, Issue:1-2

    Topics: Aged; Anticoagulants; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Interactions; Esophag

2005
Complications of percutaneous transaxillary catheterization for arteriography and selective chemotherapy.
    AJR. American journal of roentgenology, 1976, Volume: 126, Issue:2

    Topics: Adult; Aged; Angiography; Aortography; Arterial Occlusive Diseases; Axillary Artery; Catheterization

1976