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fluorouracil and Hematologic Neoplasms

fluorouracil has been researched along with Hematologic Neoplasms in 6 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Hematologic Neoplasms: Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES.

Research Excerpts

ExcerptRelevanceReference
" Chemotherapy dose-banding is a method of rationalising parenteral chemotherapy dosing and supply, whereby patient-individualised doses are rounded to predetermined banded doses."1.51Introduction of a dose-banding system for parenteral chemotherapy on a haematology-oncology day ward. ( Collins, A; Henman, MC; King, F; O'Leary, CE, 2019)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
O'Leary, CE1
Collins, A1
Henman, MC1
King, F1
Li, PJ1
Mo, HY1
Luo, DH1
Hu, WH1
Jin, T1
Kleibl, Z1
Fidlerova, J1
Kleiblova, P1
Kormunda, S1
Bilek, M1
Bouskova, K1
Sevcik, J1
Novotny, J1
Knudsen, LM1
Gaarsdal, E1
Jensen, L1
Nielsen, KJ1
Nikolaisen, K1
Johnsen, HE1
Sekine, I1
Fukuda, H1
Kunitoh, H1
Saijo, N1
Haller, DG1

Reviews

2 reviews available for fluorouracil and Hematologic Neoplasms

ArticleYear
Cancer chemotherapy in the elderly.
    Japanese journal of clinical oncology, 1998, Volume: 28, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anthraquinones; Antineoplastic Agents; Breast Neo

1998
Safety of oxaliplatin in the treatment of colorectal cancer.
    Oncology (Williston Park, N.Y.), 2000, Volume: 14, Issue:12 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Clinical Trials,

2000

Other Studies

4 other studies available for fluorouracil and Hematologic Neoplasms

ArticleYear
Introduction of a dose-banding system for parenteral chemotherapy on a haematology-oncology day ward.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2019, Volume: 25, Issue:2

    Topics: Body Surface Area; Fluorouracil; Hematologic Neoplasms; Humans; Pharmacists; Surveys and Questionnai

2019
The efficacy of induction chemotherapy in the treatment of stage II nasopharyngeal carcinoma in intensity modulated radiotherapy era.
    Oral oncology, 2018, Volume: 85

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Chemo

2018
Influence of dihydropyrimidine dehydrogenase gene (DPYD) coding sequence variants on the development of fluoropyrimidine-related toxicity in patients with high-grade toxicity and patients with excellent tolerance of fluoropyrimidine-based chemotherapy.
    Neoplasma, 2009, Volume: 56, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Deo

2009
Improved priming for mobilization of and optimal timing for harvest of peripheral blood stem cells.
    Journal of hematotherapy, 1996, Volume: 5, Issue:4

    Topics: Adolescent; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Bloo

1996
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