fluorouracil has been researched along with Hematologic Malignancies in 6 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Chemotherapy dose-banding is a method of rationalising parenteral chemotherapy dosing and supply, whereby patient-individualised doses are rounded to predetermined banded doses." | 1.51 | Introduction of a dose-banding system for parenteral chemotherapy on a haematology-oncology day ward. ( Collins, A; Henman, MC; King, F; O'Leary, CE, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| O'Leary, CE | 1 |
| Collins, A | 1 |
| Henman, MC | 1 |
| King, F | 1 |
| Li, PJ | 1 |
| Mo, HY | 1 |
| Luo, DH | 1 |
| Hu, WH | 1 |
| Jin, T | 1 |
| Kleibl, Z | 1 |
| Fidlerova, J | 1 |
| Kleiblova, P | 1 |
| Kormunda, S | 1 |
| Bilek, M | 1 |
| Bouskova, K | 1 |
| Sevcik, J | 1 |
| Novotny, J | 1 |
| Knudsen, LM | 1 |
| Gaarsdal, E | 1 |
| Jensen, L | 1 |
| Nielsen, KJ | 1 |
| Nikolaisen, K | 1 |
| Johnsen, HE | 1 |
| Sekine, I | 1 |
| Fukuda, H | 1 |
| Kunitoh, H | 1 |
| Saijo, N | 1 |
| Haller, DG | 1 |
2 reviews available for fluorouracil and Hematologic Malignancies
| Article | Year |
|---|---|
Cancer chemotherapy in the elderly.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anthraquinones; Antineoplastic Agents; Breast Neo | 1998 |
Safety of oxaliplatin in the treatment of colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Clinical Trials, | 2000 |
4 other studies available for fluorouracil and Hematologic Malignancies
| Article | Year |
|---|---|
Introduction of a dose-banding system for parenteral chemotherapy on a haematology-oncology day ward.
Topics: Body Surface Area; Fluorouracil; Hematologic Neoplasms; Humans; Pharmacists; Surveys and Questionnai | 2019 |
The efficacy of induction chemotherapy in the treatment of stage II nasopharyngeal carcinoma in intensity modulated radiotherapy era.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Chemo | 2018 |
Influence of dihydropyrimidine dehydrogenase gene (DPYD) coding sequence variants on the development of fluoropyrimidine-related toxicity in patients with high-grade toxicity and patients with excellent tolerance of fluoropyrimidine-based chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Deo | 2009 |
Improved priming for mobilization of and optimal timing for harvest of peripheral blood stem cells.
Topics: Adolescent; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Bloo | 1996 |