fluorouracil has been researched along with Helicobacter Infections in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Helicobacter Infections: Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pancreatic cancer is the fourth leading cause of cancer death in the United States." | 2.45 | Medical management of pancreatic adenocarcinoma. ( Cunha, JE; Fernandes, Gdos S; Freitas, D; Hoff, PM, 2009) |
| "Since gastric cancer (GC) cells exhibited higher grades of SHP-2 encoded by PTPN11 than normal cells, it would be intriguing to explore whether PTPN11 single nucleotide polymorphisms (SNPs) would influence chemotherapy effectiveness and GC prognosis among a Chinese population." | 1.43 | Chemotherapy Effectiveness and Prognosis of Gastric Cancer Influenced by PTPN11 Polymorphisms. ( Chen, C; Chen, G; Jiang, D; Li, J; Lin, C; Lin, X; Shao, M; Tian, H; Wang, L; Zhuo, C, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhuo, C | 1 |
| Shao, M | 1 |
| Chen, C | 1 |
| Lin, C | 1 |
| Jiang, D | 1 |
| Chen, G | 1 |
| Tian, H | 1 |
| Wang, L | 1 |
| Li, J | 1 |
| Lin, X | 1 |
| Freitas, D | 1 |
| Fernandes, Gdos S | 1 |
| Hoff, PM | 1 |
| Cunha, JE | 1 |
| Jessner, W | 1 |
| Vogelsang, H | 1 |
| Püspök, A | 1 |
| Ferenci, P | 1 |
| Gangl, A | 1 |
| Novacek, G | 1 |
| Bodisch, A | 1 |
| Wenzl, E | 1 |
| Harting, MT | 1 |
| Blakely, ML | 1 |
| Herzog, CE | 1 |
| Lally, KP | 1 |
| Ajani, JA | 1 |
| Andrassy, RJ | 1 |
1 review available for fluorouracil and Helicobacter Infections
| Article | Year |
|---|---|
Medical management of pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Aged; Aging; Antineoplastic Agents; Black People; Capecitabine; Deoxycytidine; Diabe | 2009 |
3 other studies available for fluorouracil and Helicobacter Infections
| Article | Year |
|---|---|
Chemotherapy Effectiveness and Prognosis of Gastric Cancer Influenced by PTPN11 Polymorphisms.
Topics: Aged; Alleles; Antineoplastic Agents; Case-Control Studies; Cisplatin; Female; Fluorouracil; Gene Ex | 2016 |
Plummer-Vinson syndrome associated with celiac disease and complicated by postcricoid carcinoma and carcinoma of the tongue.
Topics: Anemia, Iron-Deficiency; Antineoplastic Agents; Carboplatin; Carcinoma, Squamous Cell; Celiac Diseas | 2003 |
Treatment issues in pediatric gastric adenocarcinoma.
Topics: Anastomosis, Roux-en-Y; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Sig | 2004 |