fluorouracil has been researched along with Hamartoma in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Hamartoma: A focal malformation resembling a neoplasm, composed of an overgrowth of mature cells and tissues that normally occur in the affected area.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a patient with an intrahepatic biliary hamartoma associated with transformation to undifferentiated carcinoma which responded to intrahepatic arterial floxuridine chemotherapy." | 7.70 | A cystic biliary tumour responding to regional fluorinated pyrimidine infusion. ( Allen-Mersh, TG; Burke, D; Hedayati, B; Shousha, S, 1998) |
| "We describe a patient with an intrahepatic biliary hamartoma associated with transformation to undifferentiated carcinoma which responded to intrahepatic arterial floxuridine chemotherapy." | 3.70 | A cystic biliary tumour responding to regional fluorinated pyrimidine infusion. ( Allen-Mersh, TG; Burke, D; Hedayati, B; Shousha, S, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nelson, BR | 1 |
| Kolansky, G | 1 |
| Gillard, M | 1 |
| Ratner, D | 1 |
| Johnson, TM | 1 |
| Hedayati, B | 1 |
| Burke, D | 1 |
| Shousha, S | 1 |
| Allen-Mersh, TG | 1 |
| Kim, JJ | 1 |
| Chang, MW | 1 |
| Shwayder, T | 1 |
3 other studies available for fluorouracil and Hamartoma
| Article | Year |
|---|---|
Management of linear verrucous epidermal nevus with topical 5-fluorouracil and tretinoin.
Topics: Administration, Topical; Child; Fluorouracil; Hamartoma; Humans; Male; Neck; Occlusive Dressings; Sk | 1994 |
A cystic biliary tumour responding to regional fluorinated pyrimidine infusion.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract | 1998 |
Topical tretinoin and 5-fluorouracil in the treatment of linear verrucous epidermal nevus.
Topics: Antimetabolites; Child; Drug Combinations; Fluorouracil; Hamartoma; Humans; Keratolytic Agents; Male | 2000 |