fluorouracil has been researched along with Guillain-Barre Syndrome in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Guillain-Barre Syndrome: An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of acute inflammatory demyelinating polyradiculoneuropathy (AIDP) that developed in a patient with cholangiocarcinoma after receiving oxaliplatin-based chemotherapy." | 1.38 | Acute inflammatory demyelinating polyradiculoneuropathy in a patient receiving oxaliplatin-based chemotherapy. ( Bae, WK; Cho, SH; Chung, IJ; Hwang, JE; Kim, MK; Nam, TS; Shim, HJ; Yoon, JY, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoon, JY | 1 |
| Nam, TS | 1 |
| Kim, MK | 1 |
| Hwang, JE | 1 |
| Shim, HJ | 1 |
| Cho, SH | 1 |
| Chung, IJ | 1 |
| Bae, WK | 1 |
| Christodoulou, C | 1 |
| Anastasopoulos, D | 1 |
| Visvikis, A | 1 |
| Mellou, S | 1 |
| Detsi, I | 1 |
| Tsiakalos, G | 1 |
| Pateli, A | 1 |
| Klouvas, G | 1 |
| Papadimitriou, A | 1 |
| Skarlos, DV | 1 |
2 other studies available for fluorouracil and Guillain-Barre Syndrome
| Article | Year |
|---|---|
Acute inflammatory demyelinating polyradiculoneuropathy in a patient receiving oxaliplatin-based chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Cholangiocarcinoma; Fluorouraci | 2012 |
Guillain-Barré syndrome in a patient with metastatic colon cancer receiving oxaliplatin-based chemotherapy.
Topics: Adenocarcinoma; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; Guillain-Barre Syndrome; Hum | 2004 |