Page last updated: 2024-10-27

fluorouracil and Granulomatosis, Wegener's

fluorouracil has been researched along with Granulomatosis, Wegener's in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"Two fatal cases of interstitial pneumonitis rapidly evolving to pulmonary fibrosis are reported here."1.35Fatal pneumonitis induced by oxaliplatin. ( Arévalo Lobera, S; Azkue Gabilondo, M; Basterretxea Badiola, L; Egaña Otaño, L; Elejoste Echeberría, I; La Casta Muñoa, A; Melé Olivé, M; Sagastibeltza Mariñelarena, N, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arévalo Lobera, S1
Sagastibeltza Mariñelarena, N1
Elejoste Echeberría, I1
Melé Olivé, M1
Egaña Otaño, L1
Basterretxea Badiola, L1
La Casta Muñoa, A1
Azkue Gabilondo, M1
Vénat-Bouvet, L1
Saint-Marcoux, F1
Lagarde, C1
Peyronnet, P1
Lebrun-Ly, V1
Tubiana-Mathieu, N1

Other Studies

2 other studies available for fluorouracil and Granulomatosis, Wegener's

ArticleYear
Fatal pneumonitis induced by oxaliplatin.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2008, Volume: 10, Issue:11

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protoc

2008
Irinotecan-based chemotherapy in a metastatic colorectal cancer patient under haemodialysis for chronic renal dysfunction: two cases considered.
    Anti-cancer drugs, 2007, Volume: 18, Issue:8

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Ch

2007