fluorouracil has been researched along with Granuloma Gangraenescens in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| VONLEDEN, H | 1 |
| SCHIFF, M | 1 |
| von Leden, H | 1 |
2 other studies available for fluorouracil and Granuloma Gangraenescens
| Article | Year |
|---|---|
ANTIMETABOLITE THERAPY IN MIDLINE LETHAL GRANULOMA.
Topics: Antimetabolites; Autoimmune Diseases; DNA; Drug Therapy; Fluorouracil; Granuloma; Granuloma, Lethal | 1964 |
[Arterial chemotherapy in granuloma gangraenescens].
Topics: Adult; Carotid Arteries; Female; Fluorouracil; Granuloma, Lethal Midline; Humans; Injections, Intra- | 1965 |