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fluorouracil and Gram-Negative Bacterial Infections

fluorouracil has been researched along with Gram-Negative Bacterial Infections in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Gram-Negative Bacterial Infections: Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method.

Research Excerpts

ExcerptRelevanceReference
"5-fluorouracil was given at a dose of 1000 mg/m2 for 5 consecutive days and cisplatin was given on day 2 at a dose of 100 mg/m2."2.68The French experience with infusional 5-FU in gastric and pancreatic cancer. ( Ducreux, M; Rougier, P, 1996)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Houssany, S1
Renner, J1
Boutonnet, M1
Peigne, V1
Soler, C1
Ducreux, M1
Rougier, P1

Trials

1 trial available for fluorouracil and Gram-Negative Bacterial Infections

ArticleYear
The French experience with infusional 5-FU in gastric and pancreatic cancer.
    The Journal of infusional chemotherapy, 1996,Fall, Volume: 6, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Bio

1996

Other Studies

1 other study available for fluorouracil and Gram-Negative Bacterial Infections

ArticleYear
[Septic shock and Tissierella praeacuta].
    Medecine et maladies infectieuses, 2016, Volume: 46, Issue:1

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cholecystectomy; Cholecystitis

2016