fluorouracil has been researched along with Graft-Versus-Host Disease in 7 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fluorouracil is a common cause of acral erythema and a variety of pigmentary anomalies." | 7.68 | Combination chemotherapy with 5-fluorouracil, folinic acid, and alpha-interferon producing histologic features of graft-versus-host disease. ( Beard, JS; Skelton, HG; Smith, KJ, 1993) |
| "Fluorouracil is a common cause of acral erythema and a variety of pigmentary anomalies." | 3.68 | Combination chemotherapy with 5-fluorouracil, folinic acid, and alpha-interferon producing histologic features of graft-versus-host disease. ( Beard, JS; Skelton, HG; Smith, KJ, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, AW | 1 |
| Lalor, LE | 1 |
| Bellodi Schmidt, F | 1 |
| Luu, M | 1 |
| Kawamoto, T | 1 |
| Nihei, K | 1 |
| Doki, N | 1 |
| Najima, Y | 1 |
| Kaito, S | 1 |
| Karasawa, K | 1 |
| Konda, S | 1 |
| Patel, VA | 1 |
| O'Bryan, KW | 1 |
| Ratner, D | 1 |
| Quéméneur, L | 1 |
| Beloeil, L | 1 |
| Michallet, MC | 1 |
| Angelov, G | 1 |
| Tomkowiak, M | 1 |
| Revillard, JP | 1 |
| Marvel, J | 1 |
| Beard, JS | 1 |
| Smith, KJ | 1 |
| Skelton, HG | 1 |
| Quesenberry, PJ | 1 |
| Stewart, FM | 1 |
| Becker, P | 1 |
| D'Hondt, L | 1 |
| Frimberger, A | 1 |
| Lambert, JF | 1 |
| Colvin, GA | 1 |
| Miller, C | 1 |
| Heyes, C | 1 |
| Abedi, M | 1 |
| Dooner, M | 1 |
| Carlson, J | 1 |
| Reilly, J | 1 |
| McAuliffe, C | 1 |
| Stencel, K | 1 |
| Ballen, K | 1 |
| Emmons, R | 1 |
| Doyle, P | 1 |
| Zhong, S | 1 |
| Wang, H | 1 |
| Habibian, H | 1 |
| Tokuda, N | 1 |
| Mayumi, H | 1 |
| Himeno, K | 1 |
| Gondo, H | 1 |
| Fan, JL | 1 |
| Nomoto, K | 1 |
1 review available for fluorouracil and Graft-Versus-Host Disease
| Article | Year |
|---|---|
Stem cell engraftment strategies.
Topics: Adolescent; Adult; Aged; Animals; Antibodies, Monoclonal; Antigens, Ly; Apoptosis; CD40 Antigens; CD | 2001 |
6 other studies available for fluorouracil and Graft-Versus-Host Disease
| Article | Year |
|---|---|
A pediatric case of squamous cell cancer in situ in the setting of sclerodermatous graft-versus-host disease and voriconazole treatment.
Topics: Administration, Topical; Antifungal Agents; Bone Marrow Transplantation; Carcinoma, Squamous Cell; D | 2018 |
[Definitive Radiotherapy for Esophageal Squamous Cell Carcinoma after Allogeneic Hematopoietic Stem Cell Transplantation with Conditioning of Total Body Irradiation].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cisplatin; Esophageal Neoplasms; | 2018 |
Fibrohistiocytic tumors in a lung transplant patient taking oral capecitabine for nonmelanoma skin cancer chemoprevention.
Topics: Acitretin; Aged; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma, Basal Cell; Carcinoma, Sq | 2014 |
Restriction of de novo nucleotide biosynthesis interferes with clonal expansion and differentiation into effector and memory CD8 T cells.
Topics: Adoptive Transfer; Animals; CD8-Positive T-Lymphocytes; Cell Differentiation; Cytotoxicity, Immunolo | 2004 |
Combination chemotherapy with 5-fluorouracil, folinic acid, and alpha-interferon producing histologic features of graft-versus-host disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Eruptions; Erythema; Female; Fluorouracil; Graf | 1993 |
Drug-induced in vitro tolerance to allogeneic antigens. II. Further analysis of in vitro-tolerized spleen cells in a fully allogeneic murine combination.
Topics: Animals; Animals, Newborn; Crosses, Genetic; Cytotoxicity, Immunologic; Fluorouracil; Graft vs Host | 1988 |