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fluorouracil and Glomerulonephritis

fluorouracil has been researched along with Glomerulonephritis in 5 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Glomerulonephritis: Inflammation of the renal glomeruli (KIDNEY GLOMERULUS) that can be classified by the type of glomerular injuries including antibody deposition, complement activation, cellular proliferation, and glomerulosclerosis. These structural and functional abnormalities usually lead to HEMATURIA; PROTEINURIA; HYPERTENSION; and RENAL INSUFFICIENCY.

Research Excerpts

ExcerptRelevanceReference
" Here, we investigated a safe and efficient dosing schedule of oxaliplatin in folinic acid, fluorouracil, and oxaliplatin (FOLFOX) regimen by monitoring total and free platinum concentrations in plasma."1.51Dose-escalation of oxaliplatin in hemodialysis patient treated with FOLFOX therapy: A case report. ( Cai, X; Fang, W; Gu, Y; Li, X; Wang, D; Wang, J; Wang, Y; Xu, L; Zhao, F, 2019)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, D1
Li, X1
Xu, L1
Fang, W1
Cai, X1
Wang, Y2
Wang, J1
Zhao, F1
Gu, Y1
Watayo, Y1
Kuramochi, H1
Hayashi, K1
Nakajima, G1
Kamikozuru, H1
Yamamoto, M1
de Almeida, DB1
Curi, PR1
Lorenz, M1
Regele, H1
Kovarik, J1
Hörl, WH1
Klauser, R1
Goldstein, D1
Kelly, R1
Ralston, M1
Penny, R1
Hayes, J1

Other Studies

5 other studies available for fluorouracil and Glomerulonephritis

ArticleYear
Dose-escalation of oxaliplatin in hemodialysis patient treated with FOLFOX therapy: A case report.
    Medicine, 2019, Volume: 98, Issue:44

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chronic Disease; Colonic Neoplasms; Dose-Response Re

2019
Drug monitoring during FOLFOX6 therapy in a rectal cancer patient on chronic hemodialysis.
    Japanese journal of clinical oncology, 2010, Volume: 40, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Chronic Disease; Drug Monitoring;

2010
Treatment of rat nephrotoxic nephritis. Use of 5-fluorouracil or methotrexate-5-fluorouracil association.
    Clinical and experimental immunology, 1984, Volume: 57, Issue:3

    Topics: Animals; Drug Therapy, Combination; Fluorescent Antibody Technique; Fluorouracil; Glomerulonephritis

1984
Rapidly progressive glomerulonephritis and carcinoma of the hypopharynx.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 37, Issue:1

    Topics: Brachytherapy; Fluorouracil; Glomerulonephritis; Humans; Hypopharyngeal Neoplasms; Male; Middle Aged

2001
Chemotherapy influencing the course of nephrotic syndrome in colonic carcinoma.
    Medical oncology and tumor pharmacotherapy, 1987, Volume: 4, Issue:2

    Topics: Adenocarcinoma, Mucinous; Biopsy; Colonic Neoplasms; Fluorouracil; Glomerulonephritis; Humans; Immun

1987