fluorouracil has been researched along with Glomerulonephritis in 5 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Glomerulonephritis: Inflammation of the renal glomeruli (KIDNEY GLOMERULUS) that can be classified by the type of glomerular injuries including antibody deposition, complement activation, cellular proliferation, and glomerulosclerosis. These structural and functional abnormalities usually lead to HEMATURIA; PROTEINURIA; HYPERTENSION; and RENAL INSUFFICIENCY.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we investigated a safe and efficient dosing schedule of oxaliplatin in folinic acid, fluorouracil, and oxaliplatin (FOLFOX) regimen by monitoring total and free platinum concentrations in plasma." | 1.51 | Dose-escalation of oxaliplatin in hemodialysis patient treated with FOLFOX therapy: A case report. ( Cai, X; Fang, W; Gu, Y; Li, X; Wang, D; Wang, J; Wang, Y; Xu, L; Zhao, F, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, D | 1 |
| Li, X | 1 |
| Xu, L | 1 |
| Fang, W | 1 |
| Cai, X | 1 |
| Wang, Y | 2 |
| Wang, J | 1 |
| Zhao, F | 1 |
| Gu, Y | 1 |
| Watayo, Y | 1 |
| Kuramochi, H | 1 |
| Hayashi, K | 1 |
| Nakajima, G | 1 |
| Kamikozuru, H | 1 |
| Yamamoto, M | 1 |
| de Almeida, DB | 1 |
| Curi, PR | 1 |
| Lorenz, M | 1 |
| Regele, H | 1 |
| Kovarik, J | 1 |
| Hörl, WH | 1 |
| Klauser, R | 1 |
| Goldstein, D | 1 |
| Kelly, R | 1 |
| Ralston, M | 1 |
| Penny, R | 1 |
| Hayes, J | 1 |
5 other studies available for fluorouracil and Glomerulonephritis
| Article | Year |
|---|---|
Dose-escalation of oxaliplatin in hemodialysis patient treated with FOLFOX therapy: A case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chronic Disease; Colonic Neoplasms; Dose-Response Re | 2019 |
Drug monitoring during FOLFOX6 therapy in a rectal cancer patient on chronic hemodialysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Chronic Disease; Drug Monitoring; | 2010 |
Treatment of rat nephrotoxic nephritis. Use of 5-fluorouracil or methotrexate-5-fluorouracil association.
Topics: Animals; Drug Therapy, Combination; Fluorescent Antibody Technique; Fluorouracil; Glomerulonephritis | 1984 |
Rapidly progressive glomerulonephritis and carcinoma of the hypopharynx.
Topics: Brachytherapy; Fluorouracil; Glomerulonephritis; Humans; Hypopharyngeal Neoplasms; Male; Middle Aged | 2001 |
Chemotherapy influencing the course of nephrotic syndrome in colonic carcinoma.
Topics: Adenocarcinoma, Mucinous; Biopsy; Colonic Neoplasms; Fluorouracil; Glomerulonephritis; Humans; Immun | 1987 |