fluorouracil has been researched along with Glaucoma in 324 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To demonstrate that preoperative treatment for 28 days with topical dorzolamide/timolol is non-inferior (Δ = 4 mm Hg) to oral acetazolamide and topical dexamethasone (standard therapy) in terms of intraocular pressure (IOP) reduction 3 and 6 months after trabeculectomy in glaucoma patients." | 9.24 | Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolamide and dexamethasone eye drops and assessment of the clinical outcome of trabeculectomy in glaucoma. ( Bell, K; Keicher, A; Lorenz, K; Pfeiffer, N; Renieri, G; Ruckes, C; Thieme, H; Wasielica-Poslednik, J, 2017) |
| "To compare the efficacy of transconjunctival needling revision with 5-fluorouracil versus medical treatment in glaucomatous eyes with uncontrolled intraocular pressure due to encapsulated bleb after trabeculectomy." | 9.17 | Early transconjunctival needling revision with 5-fluorouracil versus medical treatment in encapsulated blebs: a 12-month prospective study. ( Susanna, R; Suzuki, R, 2013) |
| "To compare the effectiveness of trabeculectomy with adjunctive, low-dose, subconjunctival 5-fluorouracil (5-FU) to trabeculectomy alone in patients with uncomplicated glaucoma undergoing their first incisional surgical procedure." | 9.09 | Low-dose 5-fluorouracil trabeculectomy as initial surgery in uncomplicated glaucoma: long-term followup. ( Liebmann, JM; Ritch, R; Rothman, RF, 2000) |
| "In a randomized clinical trial, the authors compared the use of postoperative subconjunctival injections of 5-fluorouracil (5-FU) in 19 eyes with a single intraoperative application of subconjunctival mitomycin (MMC) at the filtering site in 20 eyes at high risk for failure of glaucoma filtering surgery." | 9.07 | Intraoperative mitomycin versus postoperative 5-fluorouracil in high-risk glaucoma filtering surgery. ( Beeson, CC; Bergstrom, TJ; Falck, FY; Higginbotham, EJ; Klein, TB; Lichter, PR; Musch, DC; Skuta, GL, 1992) |
| "A study was performed to examine the effect of a localized and sustained delivery of 5-fluorouracil (5-FU) on the success of glaucoma filtration surgery in 18 rabbits in a prospective, randomized, double-masked and placebo-controlled fashion." | 9.06 | The use of bioerodible polymers and 5-fluorouracil in glaucoma filtration surgery. ( Eng, CT; Glasgow, BJ; Lee, DA; Leong, KW; Panek, WC, 1988) |
| " We concluded mitomycin C might be more effective in reducing intraocular pressure and increasing qualified success compared to 5-fluorouracil." | 8.98 | Is mytomicyn better than 5-fluorouracil as antimetabolite in trabeculectomy for glaucoma? ( Pimentel, E; Schmidt, J, 2018) |
| "The objective of this review is to assess the effects of post-operative injections of 5-Fluorouracil in eyes of people undergoing surgery for glaucoma." | 8.81 | Post-operative 5-Fluorouracil for glaucoma surgery. ( Bunce, C; Wilkins, MR; Wormald, R, 2001) |
| "The objective of this review is to assess the effects of post-operative injections of 5-Fluorouracil in eyes of people undergoing surgery for glaucoma." | 8.80 | Post-operative 5-fluorouracil for glaucoma surgery. ( Bunce, C; Wilkins, MR; Wormald, R, 2000) |
| "To develop a sustained release 5-fluorouracil (5-FU) implant by three-dimensional (3D) printing to effectively prevent conjunctival fibrosis after glaucoma surgery." | 8.31 | 3D-printed long-acting 5-fluorouracil implant to prevent conjunctival fibrosis in glaucoma. ( Di Luca, M; Ioannou, N; Lamprou, DA; Luo, J; Mathew, E; Qin, M; Tagalakis, AD; Yu-Wai-Man, C, 2023) |
| "To report the effectiveness and safety of 5-fluorouracil (5-FU)-augmented Xen45 implantation in primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PEXG)." | 8.02 | Results of fluorouracil-augmented Xen45 implantation in primary open-angle and pseudoexfoliation glaucoma. ( Başer, EF; Seymenoğlu, RG, 2021) |
| "To investigate the outcomes of trabeculectomy with 5-fluorouracil (5-FU) with or without subconjunctival bevacizumab in the surgical management of pseudoexfoliation glaucoma (PXG)." | 7.91 | Initial trabeculectomy with 5-fluorouracil with or without subconjunctival bevacizumab in the management of pseudoexfoliation glaucoma. ( Çolak, S; Elgin, U; Sen, E; Yılmazbas, P, 2019) |
| "To report our experience on treatment of primary congenital glaucoma with trabeculectomy in combination with biological amniotic membranes soaked with 5-fluorouracil." | 7.88 | Retrospective observation on trabeculectomy of primary congenital glaucoma by applying biological amniotic membranes soaked with 5-fluorouracil. ( Gao, H; Guo, B; Liu, C; Liu, W; Wang, J; Wang, X; Wu, M; Zhang, C, 2018) |
| "To examine the effect of mitomycin c and 5-flurouracil on treatment outcomes following Ahmed glaucoma valve implantation." | 7.85 | Effect of mitomycin c and 5-flurouracil adjuvant therapy on the outcomes of Ahmed glaucoma valve implantation. ( Cui, QN; Han, Y; Hsia, YC; Lin, SC; Mehta, N; Naseri, A; Porco, TC; Rose-Nussbaumer, J; Stamper, RL, 2017) |
| "This study was designed to investigate whether 5-fluorouracil (5-Fu)-polycaprolactone sustained-release film in Ahmed glaucoma valve implantation inhibits postoperative bleb scarring in rabbit eyes." | 7.81 | Application of 5-Fluorouracil-Polycaprolactone Sustained-Release Film in Ahmed Glaucoma Valve Implantation Inhibits Postoperative Bleb Scarring in Rabbit Eyes. ( Bi, XZ; Li, CH; Nan, KH; Pan, WH; Ren, ZJ; Song, ZM; Sun, M; Yu, XP, 2015) |
| "To evaluate the antimitotic and toxic effects of 5-chlorouracil (5-CU) and 5-fluorouracil (5-FU) and study their potential to delay filtering bleb closure in the rabbit eye when released by poly(ortho esters) (POE)." | 7.74 | Controlled delivery of 5-chlorouracil using poly(ortho esters) in filtering surgery for glaucoma. ( Behar-Cohen, F; BenEzra, D; Bourges, JL; Felt, O; Gurny, R; Jeanny, JC; Polak, MB; Rat, P; Thomas-Doyle, A; Torriglia, A; Valamanesh, F, 2008) |
| "Although adjunctive postoperative 5-fluorouracil (5-FU) injections are known to improve the success rate of glaucoma surgery, it is still unknown what dose, timing and frequency of application will give the best results with respect to the inhibition of postoperative scarring and intraocular pressure regulation." | 7.74 | Dose, timing and frequency of subconjunctival 5-fluorouracil injections after glaucoma filtering surgery. ( Bartz-Schmidt, KU; Besch, D; Denk, PO; Grüb, M; Reinthal, EK, 2007) |
| "This study was designed to evaluate the long-term effect of phacoemulsification, lens implantation combined with trabeculectomy augmented with 5-Fluorouracil (phaco-trab-5-Fu) in Asian glaucoma patients with primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG)." | 7.73 | [The long-term effect of phacoemulsification combined with trabeculectomy and intraoperative 5-fluorouracil in glaucoma patients]. ( Cai, Y; Li, MY; Lim, BA; Lim, Z; Oen, F; Seah, S; Yan, XM, 2005) |
| "To prospectively study the evolution of possible high risk features of conjunctival filtration blebs like avascularity, transconjunctival oozing (TCO), and leaks after mitomycin C (MMC) enhanced glaucoma surgery." | 7.73 | Mitomycin C augmented glaucoma surgery: evolution of filtering bleb avascularity, transconjunctival oozing, and leaks. ( Anand, N; Arora, S; Clowes, M, 2006) |
| "To investigate the changes of tear film functions due to the use of postoperative 5-fluourouracil (5-Fu) and intraoperative mitomycin C (MMC) in glaucoma filtration surgery." | 7.71 | [Influence on tear film of postoperative 5-fluourouracil and intraoperative mitomycin C in glaucoma filtration surgery]. ( Li, J; Pang, L, 2001) |
| "The authors evaluate the results of preoperative 5-minute administration of 5-fluorouracil (5-FU), 50 mg/ml, during trabeculectomy on 11 high risk eyes of children with primary and secondary glaucoma." | 7.70 | [Peroperative administration of 5-fluorouracil during trabeculectomy in complicated glaucoma in children]. ( Burdová, M; Filous, A, 1998) |
| "To determine the effect of intraoperative application of 5-fluorouracil (5-FU) on the long-term outcome of trabeculectomy in uveitis-related glaucoma." | 7.70 | Long-term follow-up of trabeculectomy with intraoperative 5-fluorouracil for uveitis-related glaucoma. ( Lightman, S; McCluskey, P; Shaer, B; Towler, HM, 2000) |
| "Patients with both cataract and glaucoma underwent combined mitomycin C trabeculectomy, extracapsular cataract extraction, and intraocular lens implantation." | 7.69 | One-year follow-up results of combined mitomycin C trabeculectomy and extracapsular cataract extraction. ( Bueche, MJ; Feuer, WJ; Grajewski, AL; Joos, KM; Palmberg, PF, 1995) |
| "Between 2/1991 and 1/1993 twenty-nine eyes of 11 female and 16 male patients with high-risk glaucoma (unsuccessful previous filtering surgery and a high risk of scarring) were treated with subconjunctival injections of 5-Fluorouracil after filtering surgery in the University Eye Hospital Düsseldorf." | 7.68 | [5-fluorouracil injection treatment after fistulating glaucoma operations]. ( Klüppel, M; Reinhard, T; Sundmacher, R, 1993) |
| "We studied 105 patients (105 eyes) operated on for glaucoma with adjunctive fluorouracil, who were followed up for 12 to 48 months (mean, 34." | 7.68 | Late complications after glaucoma filtering surgery with adjunctive 5-fluorouracil. ( Ophir, A; Ticho, U, 1993) |
| "Twenty-one eyes of 18 patients with uncontrolled glaucoma and intraocular inflammatory disease had glaucoma filtering surgery with postoperative subconjunctival 5-fluorouracil (5-FU)." | 7.68 | Glaucoma filtering surgery with postoperative 5-fluorouracil in patients with intraocular inflammatory disease. ( Lowder, CY; Meisler, DM; Patitsas, CJ; Rockwood, EJ, 1992) |
| "The authors give an account of the results of trabeculectomy with the use of 5-fluorouracil in a group of 8 patients with complicated glaucoma." | 7.68 | [Use of 5-fluorouracil in complicated cases of glaucoma--personal experience]. ( Liehneová, I; Rozsíval, P, 1992) |
| "Trabeculectomy and subsequent subconjunctival injections of 5-fluorouracil (5-FU) were performed in four eyes (two children) with congenital glaucoma." | 7.68 | Subconjunctival injection of 5-fluorouracil following trabeculectomy for congenital and infantile glaucoma. ( Leiba, H; Oliver, M; Zalish, M, 1992) |
| "The effectiveness of trabeculectomy with adjunctive low-dose 5-fluorouracil (5-FU) as the initial surgical procedure in uncomplicated glaucoma was evaluated retrospectively in a consecutive series of 52 patients (mean follow-up, 18." | 7.68 | Initial 5-fluorouracil trabeculectomy in uncomplicated glaucoma. ( Liebmann, JM; Marmor, M; Nunez, J; Ritch, R; Wolner, B, 1991) |
| "The incidence of late-onset bleb-related endophthalmitis was evaluated retrospectively in 229 consecutive trabeculectomies performed with adjunctive 5-fluorouracil (5-FU) therapy." | 7.68 | Late bleb-related endophthalmitis after trabeculectomy with adjunctive 5-fluorouracil. ( Liebmann, JM; Marmor, M; Ritch, R; Sassani, JW; Speaker, M; Wolner, B, 1991) |
| "Nine patients (nine eyes) with iridocorneal endothelial (ICE) syndrome underwent trabeculectomy and received postoperative subconjunctival injections of 5-fluorouracil (5-FU) to enhance bleb formation (total 5-FU dose, 30-105 mg; mean, 53." | 7.68 | 5-Fluorouracil after trabeculectomy and the iridocorneal endothelial syndrome. ( Cristol, SM; Grajewski, AL; Parrish, RK; Wright, MM, 1991) |
| "We reviewed the records of 12 eyes of ten adult patients with inflammatory glaucoma who underwent trabeculectomy with the adjuvant use of 5-fluorouracil between January 1986 and January 1989." | 7.68 | Trabeculectomy with 5-fluorouracil for adult inflammatory glaucoma. ( Jabs, DA; Jampel, HD; Quigley, HA, 1990) |
| "5-Fluorouracil (5-FU) was injected subconjunctivally after glaucoma filtering surgery in a pilot study of eyes with poor surgical prognoses." | 7.67 | 5-fluorouracil and glaucoma filtering surgery. II. A pilot study. ( Anderson, DR; Gressel, MG; Heuer, DK; Hodapp, E; Palmberg, PF; Parrish, RK, 1984) |
| "We show that a 40-mg total dose of subconjunctival 5-fluorouracil after glaucoma filtering surgery can provide a success rate comparable to that demonstrated in prior studies employing a higher dose." | 7.67 | Low-dose 5-fluorouracil and glaucoma filtration surgery. ( Rabowsky, JH; Ruderman, JM, 1989) |
| "A prospective, randomized, double-masked, and placebo-controlled study was performed to examine the effect of a localized and sustained delivery of 5-fluorouracil (5-FU) on the success of glaucoma filtration surgery in 18 rabbits." | 7.67 | Glaucoma filtration surgery in rabbits using bioerodible polymers and 5-fluorouracil. ( Anderson, PJ; de Kater, AW; Flores, RA; Hertzmark, E; Lee, DA; Leong, KW; Teekhasaenee, C, 1987) |
| "The antimetabolite 5-fluorouracil (5-FU) has been used to inhibit fibroblastic growth to increase the success rate in glaucoma filtration surgery." | 7.67 | Complications of subconjunctival 5-fluorouracil following glaucoma filtering surgery. ( Hersh, P; Kersten, D; Lee, DA; Melamed, S, 1987) |
| "The effect of 5-fluorouracil (5-FU) subconjunctival injection on the bleb formation and intraocular pressure (IOP) following trabeculectomy was studied in 18 glaucoma patients (20 eyes) with poor surgical prognosis." | 7.67 | 5-Fluorouracil for trabeculectomy in glaucoma. ( Kitazawa, Y; Nakano, Y; Shirato, S; Taniguchi, T; Yamamoto, T, 1987) |
| "A life-table analysis of surgical outcomes was performed on the first eye of 155 patients who were enrolled in a pilot study of glaucoma filtering surgery with postoperative subconjunctival 5-fluorouracil (5-FU) injections." | 7.67 | Glaucoma filtering surgery with 5-fluorouracil. ( Feuer, W; Gressel, MG; Heuer, DK; Hodapp, E; Palmberg, PF; Parrish, RK; Rockwood, EJ; Skuta, GL, 1987) |
| "We studied four patients who, having received postoperative 5-fluorouracil after glaucoma filtering operations, developed serious corneal complications." | 7.67 | Serious corneal complications of glaucoma filtering surgery with postoperative 5-fluorouracil. ( Driebe, WT; Heuer, DK; Knapp, A; Stern, GA, 1987) |
| "Last controlled intraocular pressure is lower in C group patients (13." | 6.68 | [Intra- and postoperative use of 5-fluorouracil in the surgical treatment of refractory glaucoma]. ( Apatachioaie, I; Brănişteanu, D; Chiseliţă, D; Poiata, I; Rusu, V; Tătăruş, C, 1997) |
| "Late postoperative complications are similar with the exception of an increased incidence of Tenon cyst formation in the MMC-treated eyes." | 6.68 | Mitomycin C versus 5-fluorouracil in high-risk glaucoma filtering surgery. Extended follow-up. ( Bergstrom, TJ; Higginbotham, EJ; Johnson, AT; Katz, GJ; Lichter, PR; Musch, DC; Skuta, GL, 1995) |
| "These include young patients, those with pigmentary glaucoma, secondary glaucoma, angle recession glaucoma, aphakic or pseudophakic glaucoma, and patients requiring reoperation." | 6.67 | Intraoperative mitomycin C in complicated glaucomas. ( Dogra, A; Kaur, J; Singh, G, 1993) |
| "Intraocular pressure was 20 mm Hg or lower in 24 eyes (96%) in the treatment group after mean follow-up of 17." | 6.67 | A randomized study of trabeculectomy and subconjunctival administration of fluorouracil in primary glaucomas. ( Ophir, A; Ticho, U, 1992) |
| "Raised intraocular pressure is a risk factor for glaucoma." | 6.52 | Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery. ( Cabourne, E; Clarke, JC; Evans, JR; Schlottmann, PG, 2015) |
| "Mitomycin C seems to be a better treatment than 5 fluorouracil." | 6.38 | [Mitomycin C in glaucoma surgery]. ( Collignon-Brach, J, 1993) |
| "5-Fluorouracil (5-FU) has been well described for a failing trabeculectomy bleb, but not for aqueous shunts." | 5.46 | Use of subconjunctival injections of 5-fluorouracil to rescue and prolong intraocular pressure reduction for a failing Ahmed glaucoma implant. ( Kaplowitz, K; Khodadadeh, S; Lee, D; Tsai, JC; Wang, S, 2017) |
| " In this study, 5-Fluorouracil (5-FU), a halogenated pyrimidine analogue and a potent anti-mitotic agent, was applied for seven days after trabeculectomy in eighteen complicated and unsuccessful filtering glaucomas, at a daily dosage of 5 mg in the form of 0." | 5.29 | The role of 5-fluorouracil in complicated glaucomas. ( Das, S; Jilani, FA; Khan, AM, 1993) |
| " Whether dose reduction will lead to reduced corneal toxicity in glaucoma filtration surgery following topical or subconjunctival dosing is an interesting therapeutic opportunity that remains to be determined." | 5.28 | Corneal penetration of 5-fluorouracil and its improvement by prodrug derivatization in the albino rabbit: implication in glaucoma filtration surgery. ( Bundgaard, H; Buur, A; Lee, VH; Wang, W, 1991) |
| "The objective of this article was to study longitudinal changes in bleb morphology (presence of microcysts and bleb height and vascularity) in subjects enrolled in the Singapore 5-Fluorouracil (5-FU) trabeculectomy study." | 5.27 | Longitudinal Changes in Bleb Height, Vascularity, and Conjunctival Microcysts After Trabeculectomy. ( Aung, T; Htoon, HM; Husain, R; Kumaran, A, 2018) |
| "5-fluorouracil is an antimetabolite capable of inhibiting fibroblast proliferation." | 5.27 | 5-fluorouracil and glaucoma filtering surgery: I. An animal model. ( Folberg, R; Gressel, MG; Parrish, RK, 1984) |
| "To demonstrate that preoperative treatment for 28 days with topical dorzolamide/timolol is non-inferior (Δ = 4 mm Hg) to oral acetazolamide and topical dexamethasone (standard therapy) in terms of intraocular pressure (IOP) reduction 3 and 6 months after trabeculectomy in glaucoma patients." | 5.24 | Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolamide and dexamethasone eye drops and assessment of the clinical outcome of trabeculectomy in glaucoma. ( Bell, K; Keicher, A; Lorenz, K; Pfeiffer, N; Renieri, G; Ruckes, C; Thieme, H; Wasielica-Poslednik, J, 2017) |
| "To compare the efficacy of transconjunctival needling revision with 5-fluorouracil versus medical treatment in glaucomatous eyes with uncontrolled intraocular pressure due to encapsulated bleb after trabeculectomy." | 5.17 | Early transconjunctival needling revision with 5-fluorouracil versus medical treatment in encapsulated blebs: a 12-month prospective study. ( Susanna, R; Suzuki, R, 2013) |
| "Primary outcome was bleb vascularity with secondary endpoints including visual acuity, intraocular pressure, bleb morphology, complications and total numbers of 5-fluorouracil injections were recorded at baseline, week 12 and 18 months." | 5.16 | Bleb vascularity following post-trabeculectomy subconjunctival bevacizumab: a pilot study. ( Chua, BE; Coote, MA; Crowston, JG; Gupta, V; Nguyen, DQ; Niyadurupola, N; Qin, Q; Ruddle, JB; Wells, AP; Wong, TT, 2012) |
| "Patients aged ≥ 30 years newly diagnosed with glaucoma were randomized to trabeculectomy with 5-fluorouracil or medical therapy." | 5.16 | A study of initial therapy for glaucoma in southern India: India Glaucoma Outcomes and Treatment (INGOT) Study. ( Congdon, NG; Friedman, DS; Gilbert, D; Goggins, W; Kader, MA; Krishnadas, R; Quigley, HA; Ramakrishnan, R; Tielsch, J, 2012) |
| "The perioperative use of oral prednisone did not alter the surgical outcome of filtering procedures associated with antifibrosis agents in this population of glaucoma patients." | 5.09 | Oral prednisone in guarded filtration procedures supplemented with antimetabolites. ( Augsburger, JJ; Azuara-Blanco, A; Spaeth, GL, 1999) |
| "To compare the effectiveness of trabeculectomy with adjunctive, low-dose, subconjunctival 5-fluorouracil (5-FU) to trabeculectomy alone in patients with uncomplicated glaucoma undergoing their first incisional surgical procedure." | 5.09 | Low-dose 5-fluorouracil trabeculectomy as initial surgery in uncomplicated glaucoma: long-term followup. ( Liebmann, JM; Ritch, R; Rothman, RF, 2000) |
| "Mean (+/-SD) preoperative and 1-year postoperative intraocular pressures in the 5-fluorouracil group were 26." | 5.09 | Randomized, controlled study of low-dose 5-fluorouracil in primary trabeculectomy. ( Caprioli, J; Chaudhry, IA; O'Connor, DJ; Pasha, MA; Weitzman, ML, 2000) |
| "Trabeculectomy is the procedure of choice for the surgical control of glaucoma, and is often augmented by intraoperative 5-fluorouracil application to reduce scarring." | 5.09 | Single intraoperative application of 5-Fluorouracil versus placebo in low-risk trabeculectomy surgery: a randomized trial. ( Bloom, P; Leyland, M; McAlister, J; Migdal, C; Rassam, S; Zinicola, E, 2001) |
| "To determine the efficacy and safety of subconjunctival 5- fluorouracil injections after trabeculectomy in patients with poor prognoses, to determine risk factors for surgical failure and to examine the relationship of intraocular pressure and visual function." | 5.08 | Five-year follow-up of the Fluorouracil Filtering Surgery Study. The Fluorouracil Filtering Surgery Study Group. ( , 1996) |
| "To study the effect of 5-Fluorouracil (5-FU) in glaucoma filtration surgery, 13 eyes of 12 patients with glaucoma were subjected to trabeculectomy with intraoperative one minute exposure of 50 mg/ml 5-FU." | 5.08 | Results of intraoperative 5-fluorouracil in patients undergoing trabeculectomy--pilot trial. ( Garg, D; Rao, BS; Revathi, B; Shelat, B; Vijaya, L, 1996) |
| "The effects of postoperative subconjunctival 5-fluorouracil (5-FU) injections on the surgical outcomes of trabeculectomy were studied after a 5-year follow-up in 263 eyes of glaucoma patients by the life table analysis." | 5.07 | [A five-year follow-up of the effect of postoperative 5-fluorouracil subconjunctival injections on the surgical outcome of trabeculectomy]. ( Araie, M; Nakano, Y; Shirato, S; Shoji, N, 1993) |
| "Eighteen eyes of 15 patients with uncontrolled glaucoma (neovascular, intracapsular aphakia, uveitic, previous filtration failure) at high risk for failure of standard filtration underwent trabeculectomy with implantation of a purified collagen sponge containing 100 micrograms of antimetabolite (5-fluorouracil or bleomycin)." | 5.07 | Long-term results of trabeculectomy with collagen sponge implant containing low-dose antimetabolite. ( Herschler, J, 1992) |
| "In a randomized clinical trial, the authors compared the use of postoperative subconjunctival injections of 5-fluorouracil (5-FU) in 19 eyes with a single intraoperative application of subconjunctival mitomycin (MMC) at the filtering site in 20 eyes at high risk for failure of glaucoma filtering surgery." | 5.07 | Intraoperative mitomycin versus postoperative 5-fluorouracil in high-risk glaucoma filtering surgery. ( Beeson, CC; Bergstrom, TJ; Falck, FY; Higginbotham, EJ; Klein, TB; Lichter, PR; Musch, DC; Skuta, GL, 1992) |
| "We conducted a prospective, randomized study to compare mitomycin with fluorouracil for efficacy and safety as an adjunct to trabeculectomy in eyes with glaucoma with poor surgical prognosis." | 5.07 | Trabeculectomy with mitomycin. A comparative study with fluorouracil. ( Kawase, K; Kitazawa, Y; Matsushita, H; Minobe, M, 1991) |
| "A study was performed to examine the effect of a localized and sustained delivery of 5-fluorouracil (5-FU) on the success of glaucoma filtration surgery in 18 rabbits in a prospective, randomized, double-masked and placebo-controlled fashion." | 5.06 | The use of bioerodible polymers and 5-fluorouracil in glaucoma filtration surgery. ( Eng, CT; Glasgow, BJ; Lee, DA; Leong, KW; Panek, WC, 1988) |
| " We concluded mitomycin C might be more effective in reducing intraocular pressure and increasing qualified success compared to 5-fluorouracil." | 4.98 | Is mytomicyn better than 5-fluorouracil as antimetabolite in trabeculectomy for glaucoma? ( Pimentel, E; Schmidt, J, 2018) |
| "With the increased use of intraoperative antifibrotic (eg, mitomycin and fluorouracil) as an adjunct to standard trabeculectomy, an increased incidence is seen of late-onset filtering bleb-related infections." | 4.82 | Glaucoma-filtering bleb infections. ( Mac, I; Soltau, JB, 2003) |
| "The use of antifibrotic agents, namely, 5-fluorouracil and mitomycin C, in conjunction with glaucoma surgery has resulted in lower postoperative intraocular pressures after trabeculectomy or combined cataract and glaucoma surgery." | 4.82 | Update on antifibrotic use in glaucoma surgery, including use in trabeculectomy and glaucoma drainage implants and combined cataract and glaucoma surgery. ( Singh, K; Yoon, PS, 2004) |
| "Agents such as the antimetabolites 5-fluorouracil (5FU) and mitomycin-C (MMC) have revolutionised glaucoma surgery in patients with a high risk of surgical failure." | 4.82 | Wound healing after glaucoma surgery: how to manage it? ( Collignon, NJ, 2005) |
| "The preponderance of evidence from the literature suggests a small (2-4 mmHg) benefit from the use of mitomycin-C (MMC), but not 5-fluorouracil (5-FU), in combined cataract and glaucoma surgery (evidence grade B)." | 4.81 | Effect of technique on intraocular pressure after combined cataract and glaucoma surgery: An evidence-based review. ( Bass, EB; Congdon, N; Friedman, DS; Jampel, HD; Kempen, JH; Levkovitch-Verbin, H; Lubomski, LH; Quigley, H; Robinson, KA, 2002) |
| "To examine why most ophthalmologists routinely use mitomycin C or 5-fluorouracil (antimetabolites) in association with filtering surgery for glaucoma." | 4.81 | The use of antimetabolites with trabeculectomy: a critical appraisal. ( Mutlukan, E; Spaeth, GL, 2001) |
| "The objective of this review is to assess the effects of post-operative injections of 5-Fluorouracil in eyes of people undergoing surgery for glaucoma." | 4.81 | Post-operative 5-Fluorouracil for glaucoma surgery. ( Bunce, C; Wilkins, MR; Wormald, R, 2001) |
| " Cyclosporine A devices were prepared for the treatment of uveitis." | 4.79 | Review: implants. ( Ashton, P; Blandford, DL; Jaffe, GJ; Martin, DF; Nussenblatt, RB; Pearson, PA, 1994) |
| "Intraoperative Mitomycin C may be a helpful adjunct in achieving low final intraocular pressure after trabeculectomy in high-risk glaucoma filtering surgery, and Mitomycin C may be a viable alternative to postoperative 5-Fluorouracil." | 4.79 | [Trabeculectomy with mitomycin C. Study apropos of 30 cases]. ( Ballion, JC; Bazin, S; Ducousso, F; Poirier, L; Verin, P; Williamson, W, 1995) |
| "To develop a sustained release 5-fluorouracil (5-FU) implant by three-dimensional (3D) printing to effectively prevent conjunctival fibrosis after glaucoma surgery." | 4.31 | 3D-printed long-acting 5-fluorouracil implant to prevent conjunctival fibrosis in glaucoma. ( Di Luca, M; Ioannou, N; Lamprou, DA; Luo, J; Mathew, E; Qin, M; Tagalakis, AD; Yu-Wai-Man, C, 2023) |
| "To report the effectiveness and safety of 5-fluorouracil (5-FU)-augmented Xen45 implantation in primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PEXG)." | 4.02 | Results of fluorouracil-augmented Xen45 implantation in primary open-angle and pseudoexfoliation glaucoma. ( Başer, EF; Seymenoğlu, RG, 2021) |
| "To investigate the outcomes of trabeculectomy with 5-fluorouracil (5-FU) with or without subconjunctival bevacizumab in the surgical management of pseudoexfoliation glaucoma (PXG)." | 3.91 | Initial trabeculectomy with 5-fluorouracil with or without subconjunctival bevacizumab in the management of pseudoexfoliation glaucoma. ( Çolak, S; Elgin, U; Sen, E; Yılmazbas, P, 2019) |
| "Rabbit model studies suggested better morphology blebs with equal intraocular pressure (IOP) efficacy as a standard mitomycin C (MMC) trabeculectomy using a novel slow-release drug delivery antifibrotic system delivering small quantities of MMC and 5-fluorouracil (5-FU)." | 3.91 | Effect of 2 Novel Sustained-release Drug Release Systems on Bleb Fibrosis: An In Vivo Trabeculectomy Study in a Rabbit Model. ( Ayyala, RS; Blake, D; Fullerton, M; Greenberg, E; John, V; Le, C; Mancera, N; Margo, C; Muddasani, N; Satija, C; Singh, S; Swann, FB; Wall, J; Zhang, Z; Zurakowski, D, 2019) |
| "To report our experience on treatment of primary congenital glaucoma with trabeculectomy in combination with biological amniotic membranes soaked with 5-fluorouracil." | 3.88 | Retrospective observation on trabeculectomy of primary congenital glaucoma by applying biological amniotic membranes soaked with 5-fluorouracil. ( Gao, H; Guo, B; Liu, C; Liu, W; Wang, J; Wang, X; Wu, M; Zhang, C, 2018) |
| "To evaluate the long-term outcome of trabeculectomy with intra- and postoperative 5-fluorouracil (5-FU) application in glaucoma." | 3.85 | Three-Year Follow-Up of Trabeculectomy with 5-Fluorouracil. ( Koutsonas, A; Kuerten, D; Lindemann, F; Plange, N; Schimitzek, H, 2017) |
| "To examine the effect of mitomycin c and 5-flurouracil on treatment outcomes following Ahmed glaucoma valve implantation." | 3.85 | Effect of mitomycin c and 5-flurouracil adjuvant therapy on the outcomes of Ahmed glaucoma valve implantation. ( Cui, QN; Han, Y; Hsia, YC; Lin, SC; Mehta, N; Naseri, A; Porco, TC; Rose-Nussbaumer, J; Stamper, RL, 2017) |
| " Antimetabolites, such as mitomycin C and 5-fluorouracil, have been used for many years to increase survival time of filtration surgeries by preventing bleb fibrosis and scarring." | 3.83 | A role for antimetabolites in glaucoma tube surgery: current evidence and future directions. ( Amoozgar, B; Han, Y; Kuo, J; Lin, SC, 2016) |
| "To compare the complication rate and effectiveness of mitomycin C (MMC), Ologen alone, and Ologen with 5-fluorouracil (5-FU) as adjunctives with Ex-PRESS mini shunt for medically uncontrolled glaucoma." | 3.81 | Ex-PRESS outcomes using mitomycin-C, Ologen alone, Ologen with 5-fluorouracil. ( Han, Y; Lowry, EA; Menda, SA; Porco, TC; Rubin, MR; Stamper, RL, 2015) |
| "This study was designed to investigate whether 5-fluorouracil (5-Fu)-polycaprolactone sustained-release film in Ahmed glaucoma valve implantation inhibits postoperative bleb scarring in rabbit eyes." | 3.81 | Application of 5-Fluorouracil-Polycaprolactone Sustained-Release Film in Ahmed Glaucoma Valve Implantation Inhibits Postoperative Bleb Scarring in Rabbit Eyes. ( Bi, XZ; Li, CH; Nan, KH; Pan, WH; Ren, ZJ; Song, ZM; Sun, M; Yu, XP, 2015) |
| "To investigate the safety and efficacy of Nd:YAG laser goniopuncture (LGP) in lowering intraocular pressure (IOP) in eyes having late bleb failure following trabeculectomy with mitomycin C administration." | 3.80 | Nd:YAG laser goniopuncture for late bleb failure after trabeculectomy with adjunctive mitomycin C. ( Alencar, LM; De Moraes, CG; Ritch, R; Susanna, R, 2014) |
| "To determine whether primary trabeculectomies performed in a UK district general hospital, specifically without making use of mitomycin-C augmentation but with selective use of the low potency anti-metabolite 5-fluorouracil, produce an acceptable long-term intraocular pressure (IOP)-lowering effect for an unselected patient group." | 3.79 | Enhanced trabeculectomy in a UK district general hospital setting: is selective use of 5-fluorouracil all that is required? ( Chaudhry, N; de Klerk, TA; Moriarty, AP, 2013) |
| "to investigate the ability of drug-loaded N,O-carboxymethyl chitosan (CMCS) hydrogels to modulate wound healing after glaucoma filtration surgery." | 3.76 | Ophthalmic drug-loaded N,O-carboxymethyl chitosan hydrogels: synthesis, in vitro and in vivo evaluation. ( CAI, X; CHEN, RF; CHENG, LZ; FAN, JZ; GUO, H; LAN, YQ; YANG, LQ; ZHANG, LM; ZHOU, HS, 2010) |
| " Intraocular pressure, visual acuity, complications and numbers of injections of 5-fluorouracil, suture removal, needling procedures and visits to ophthalmologists were recorded for 2 years." | 3.75 | Trabeculectomy with an active postoperative regimen: results and resource utilization. ( Alm, A; Niemelä, P; Taube, AB, 2009) |
| "To evaluate long-term outcomes after Ahmed valve implantation in patients with glaucoma when using adjunctive intraoperative mitomycin C (MMC) and postoperative 5-fluorouracil (5-FU)." | 3.74 | Ahmed valve implantation with adjunctive mitomycin C and 5-fluorouracil: long-term outcomes. ( Alvarado, JA; Hollander, DA; Juster, RP; Lee, LC, 2008) |
| "To evaluate the antimitotic and toxic effects of 5-chlorouracil (5-CU) and 5-fluorouracil (5-FU) and study their potential to delay filtering bleb closure in the rabbit eye when released by poly(ortho esters) (POE)." | 3.74 | Controlled delivery of 5-chlorouracil using poly(ortho esters) in filtering surgery for glaucoma. ( Behar-Cohen, F; BenEzra, D; Bourges, JL; Felt, O; Gurny, R; Jeanny, JC; Polak, MB; Rat, P; Thomas-Doyle, A; Torriglia, A; Valamanesh, F, 2008) |
| "Although adjunctive postoperative 5-fluorouracil (5-FU) injections are known to improve the success rate of glaucoma surgery, it is still unknown what dose, timing and frequency of application will give the best results with respect to the inhibition of postoperative scarring and intraocular pressure regulation." | 3.74 | Dose, timing and frequency of subconjunctival 5-fluorouracil injections after glaucoma filtering surgery. ( Bartz-Schmidt, KU; Besch, D; Denk, PO; Grüb, M; Reinthal, EK, 2007) |
| "To report the experience with trabeculectomy augmented with mitomycin C and 5-fluorouracil for the treatment of paediatric glaucoma." | 3.73 | Augmented trabeculectomy in paediatric glaucoma. ( Ehrlich, R; Friling, R; Gaton, DD; Lusky, M; Snir, M; Weinberger, D, 2005) |
| "To determine the preference of members of the American Glaucoma Society for the use of antifibrotic agents (mitomycin C or 5-fluorouracil or both) and glaucoma drainage devices in ten clinical settings." | 3.73 | 2002 survey of the American Glaucoma Society: practice preferences for glaucoma surgery and antifibrotic use. ( Feuer, WF; Joshi, AB; Parrish, RK, 2005) |
| "This study was designed to evaluate the long-term effect of phacoemulsification, lens implantation combined with trabeculectomy augmented with 5-Fluorouracil (phaco-trab-5-Fu) in Asian glaucoma patients with primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG)." | 3.73 | [The long-term effect of phacoemulsification combined with trabeculectomy and intraoperative 5-fluorouracil in glaucoma patients]. ( Cai, Y; Li, MY; Lim, BA; Lim, Z; Oen, F; Seah, S; Yan, XM, 2005) |
| "In this study we compared the two groups of glaucoma patients who had underwent trabeculectomy, with or without intraoperative application of antimetabolite 5-Fluorouracile (5 FU)." | 3.73 | [Visual acuty after trabeculectomy]. ( Buzarovska, KB; Dzajkovska, E; Jordanova, VD; Vukosavljević, M, 2005) |
| "To prospectively study the evolution of possible high risk features of conjunctival filtration blebs like avascularity, transconjunctival oozing (TCO), and leaks after mitomycin C (MMC) enhanced glaucoma surgery." | 3.73 | Mitomycin C augmented glaucoma surgery: evolution of filtering bleb avascularity, transconjunctival oozing, and leaks. ( Anand, N; Arora, S; Clowes, M, 2006) |
| "To investigate the effect on intraocular pressure (IOP) of intraoperative 5-fluorouracil (5-FU) application during primary trabeculectomy in a West African population." | 3.72 | Intraoperative 5-fluorouracil application during primary trabeculectomy in Nigeria: a comparative study. ( Anand, N; Dawda, VK; Mielke, C, 2003) |
| "A retrospective chart review of 44 eyes of 44 patients with uveitic glaucoma who underwent trabeculectomy with mitomycin C or 5-fluorouracil." | 3.71 | Trabeculectomy with antiproliferative agents in uveitic glaucoma. ( Beck, AD; Ceballos, EM; Lynn, MJ, 2002) |
| "To investigate the changes of tear film functions due to the use of postoperative 5-fluourouracil (5-Fu) and intraoperative mitomycin C (MMC) in glaucoma filtration surgery." | 3.71 | [Influence on tear film of postoperative 5-fluourouracil and intraoperative mitomycin C in glaucoma filtration surgery]. ( Li, J; Pang, L, 2001) |
| "To assess the outcome of trabeculectomy supplemented with intraoperative 5-Fluorouracil (5 FU) application in glaucoma patients." | 3.70 | Modification of trabeculectomy with single-dose intraoperative 5-Fluorouracil application. ( Anand, N; Menage, MJ; Sahni, K, 1998) |
| "Bleb leakage occurred in 14 eyes following trabeculectomy (mitomycin C treatment, 10 eyes; 5-fluorouracil treatment, 3 eyes; no antifibrosis agent, 1 eye) and in 1 eye following combined cataract and glaucoma surgery with adjunctive mitomycin C therapy." | 3.70 | Late-onset bleb leaks after glaucoma filtering surgery. ( Greenfield, DS; Jee, J; Liebmann, JM; Ritch, R, 1998) |
| "The authors evaluate the results of preoperative 5-minute administration of 5-fluorouracil (5-FU), 50 mg/ml, during trabeculectomy on 11 high risk eyes of children with primary and secondary glaucoma." | 3.70 | [Peroperative administration of 5-fluorouracil during trabeculectomy in complicated glaucoma in children]. ( Burdová, M; Filous, A, 1998) |
| "This retrospective study was undertaken to evaluate if a "low dose" intraoperative sponge 5-fluorouracil application may improve the quality of the postoperative IOP control without increasing the incidence of postoperative complications following a first trabeculectomy in low-risk and/or severe field defects glaucomatous patients comparatively with a control group." | 3.70 | [Use of "low dose" 5-fluorouracil during trabeculectomy]. ( Detry-Morel, M; Kolanowski, C, 1999) |
| "The use of adjunctive antimetabolites such as 5-fluorouracil (5-FU) and mitomycin C (MMC) in trabeculectomy has caused an increased concern as to the risk of bleb-associated endophthalmitis." | 3.70 | Late-onset, bleb-associated endophthalmitis following glaucoma filtering surgery with or without antifibrotic agents. ( Frucht-Pery, J; Solomon, A; Ticho, U, 1999) |
| "To determine the effect of intraoperative application of 5-fluorouracil (5-FU) on the long-term outcome of trabeculectomy in uveitis-related glaucoma." | 3.70 | Long-term follow-up of trabeculectomy with intraoperative 5-fluorouracil for uveitis-related glaucoma. ( Lightman, S; McCluskey, P; Shaer, B; Towler, HM, 2000) |
| "To study the association between after-cataract and secondary glaucoma after lensectomy and 5-fluorouracil treatment in an experimental infant rabbit model." | 3.70 | After-cataract and secondary glaucoma in the aphakic infant rabbit. ( Holmén, JB; Kugelberg, U; Lundgren, B; Lundvall, A; Zetterström, C, 2000) |
| "A concurrent series (from January 1, 1987, to October 1, 1997) of one surgeon's consecutive 585 (456 patients) combined cataract extraction, intraocular lens implantation, and trabeculectomy surgeries, some with intraoperative mitomycin C and/or postoperative subconjunctival 5-fluorouracil." | 3.70 | Outcomes of combined cataract extraction, lens implantation, and trabeculectomy surgeries. ( Hahn, J; Larive, B; Rockwood, EJ, 2000) |
| "The cytostatic 5-fluorouracil (5-FU) is used at present in the postoperative treatment of glaucoma." | 3.70 | [Use of 5-fluorouracil in trabeculectomy]. ( Hovorková, M; Kvasnicka, J; Lochman, J; Novák, J; Rozsíval, P, 2000) |
| "To determine whether there is increased risk to the corneal endothelium when mitomycin C is used in trabeculectomy surgery instead of fluorouracil, and whether these agents play a role in accelerating cataract formation." | 3.69 | Effect of mitomycin C and fluorouracil-supplemented trabeculectomies on the anterior segment. ( Chaturvedi, N; Dreyer, EB; Zurakowski, D, 1995) |
| "Patients with both cataract and glaucoma underwent combined mitomycin C trabeculectomy, extracapsular cataract extraction, and intraocular lens implantation." | 3.69 | One-year follow-up results of combined mitomycin C trabeculectomy and extracapsular cataract extraction. ( Bueche, MJ; Feuer, WJ; Grajewski, AL; Joos, KM; Palmberg, PF, 1995) |
| "To evaluate intraocular pressure (IOP) control and surgical complications following trabeculectomy with 5-fluorouracil (5-FU) or mitomycin at the inferior limbus." | 3.69 | Trabeculectomy at the inferior limbus. ( Caronia, RM; Cohen, H; Friedman, R; Liebmann, JM; Ritch, R, 1996) |
| "Implantable monolithic and reservoir-like water-swellable drainage devices were developed for the subconjunctival sustained release of 5-fluorouracil (5-FU) in glaucoma-filtering surgery." | 3.69 | 5-FU loaded pHEMA drainage implants for glaucoma-filtering surgery: device design and in vitro release kinetics. ( Akata, RF; Gökce, M; Kiremitçi-Gümüşderelioğlu, M, 1996) |
| "5-Fluorouracil (5-FU) is useful as an adjunct treatment for glaucoma filtering surgery." | 3.69 | [Biodegradable controlled-release 5-FU implant in the surgery for glaucoma. Experimental study]. ( Hostyn, P; Kühne, F; Malek-Chehire, N; Parel, JM; Parrish RK, II; Takesue, Y; Villain, F, 1996) |
| "Administration of subconjunctival 5-fluorouracil (5-FU) and topical mitomycin-C (MMC) has been shown to improve the success rate of glaucoma-filtering surgery." | 3.69 | A novel MMC-loaded pHEMA drainage device for the treatment of glaucoma: in vitro and in vivo studies. ( Akata, RF; Gökçe, M; Kiremitçi-Gümüşderelioglu, M, 1996) |
| "A 2-month-old female infant with intractable congenital glaucoma and diffuse corneal opacification underwent trabeculectomy with 5-fluorouracil (5-FU) injection in both eyes followed by penetrating keratoplasty (PKP) combined with partial cyclocryotherapy in the right eye." | 3.69 | Ultrasonographic findings of the optic disc in congenital glaucoma. ( Barash, D; Kremer, I; Lusky, M; Snir, M; Yassur, Y, 1996) |
| " Preferences for either no antifibrosis agent (up to 39%) or 5-fluorouracil (up to 29%) were highest in primary trabeculectomy." | 3.69 | Use of antifibrosis agents and glaucoma drainage devices in the American and Japanese Glaucoma Societies. ( Chen, PP; Kitazawa, Y; Parrish, RK; Sawada, A; Yamamoto, T, 1997) |
| " Forty patients (controls; TRAB group) who had trabeculectomy alone were matched to the cases for length of follow-up, age, IOP, number of anti-glaucoma medications, number of 5-fluorouracil (5-FU) injections, race, sex and diagnosis." | 3.69 | Temporal corneal phacoemulsification in filtered glaucoma patients. ( Caprioli, J; Kwon, YH; Park, HJ; Weitzman, M, 1997) |
| "To investigate the incidence of complications reportedly caused by the use of 5-fluorouracil (5-FU) in glaucoma filtering surgery, we performed trabeculectomy with 5-FU on 57 eyes of 56 patients with advanced glaucoma." | 3.68 | Incidence of complications following 5-fluorouracil with trabeculectomies. ( Gieser, SC; Jacob, A; Raju, R; Sen, S; Thomas, R, 1993) |
| "Between 2/1991 and 1/1993 twenty-nine eyes of 11 female and 16 male patients with high-risk glaucoma (unsuccessful previous filtering surgery and a high risk of scarring) were treated with subconjunctival injections of 5-Fluorouracil after filtering surgery in the University Eye Hospital Düsseldorf." | 3.68 | [5-fluorouracil injection treatment after fistulating glaucoma operations]. ( Klüppel, M; Reinhard, T; Sundmacher, R, 1993) |
| "54 patients (66 eyes) of late primary glaucoma were divided into 5-Fluorouracil and control groups before trabeculectomy surgery." | 3.68 | [The anti-cicatrization effect of low dosage 5-Fu after trabeculectomy in late glaucoma]. ( Xiong, XL, 1993) |
| "Rabbits undergoing full-thickness glaucoma filtering surgery were exposed for 5 minutes to one of three intraoperative treatments: (1) distilled water; (2) fluorouracil, 50 mg/mL; or (3) mitomycin C, 0." | 3.68 | Prolonged localized tissue effects from 5-minute exposures to fluorouracil and mitomycin C. ( Doyle, JW; Grierson, I; Khaw, PT; McGorray, S; Schultz, G; Sherwood, MB, 1993) |
| "We measured aqueous flare in 16 glaucomatous eyes after trabeculectomy in which 5-fluorouracil (5-FU) or mitomycin C (MMC) had been used as an adjunctive therapy." | 3.68 | Anterior chamber reaction after mitomycin and 5-fluorouracil trabeculectomy: a comparative study. ( Jikihara, S; Kawase, K; Kitazawa, Y; Nishimura, K; Yamamoto, T, 1993) |
| "We studied 105 patients (105 eyes) operated on for glaucoma with adjunctive fluorouracil, who were followed up for 12 to 48 months (mean, 34." | 3.68 | Late complications after glaucoma filtering surgery with adjunctive 5-fluorouracil. ( Ophir, A; Ticho, U, 1993) |
| " These observations have lead to the widespread clinical use in humans of 5-fluorouracil and more recently mitomycin-C in glaucoma filtering surgery." | 3.68 | Antimetabolites in the surgical treatment of glaucomas. ( Van Caelenberghe, E; Van Oye, R, 1992) |
| "Twenty-one eyes of 18 patients with uncontrolled glaucoma and intraocular inflammatory disease had glaucoma filtering surgery with postoperative subconjunctival 5-fluorouracil (5-FU)." | 3.68 | Glaucoma filtering surgery with postoperative 5-fluorouracil in patients with intraocular inflammatory disease. ( Lowder, CY; Meisler, DM; Patitsas, CJ; Rockwood, EJ, 1992) |
| "Trabeculectomy and subsequent subconjunctival injections of 5-fluorouracil (5-FU) were performed in four eyes (two children) with congenital glaucoma." | 3.68 | Subconjunctival injection of 5-fluorouracil following trabeculectomy for congenital and infantile glaucoma. ( Leiba, H; Oliver, M; Zalish, M, 1992) |
| "Repeated doses of 5mg of 5-fluorouracil (5-FU) were injected subconjunctivally in 25 poor-prognosis glaucomatous eyes after filtering surgery to prevent filtering bleb scarring." | 3.68 | Regulating the dose of 5-fluorouracil to prevent filtering bleb scarring. ( Ophir, A; Ticho, U, 1991) |
| "The effectiveness of trabeculectomy with adjunctive low-dose 5-fluorouracil (5-FU) as the initial surgical procedure in uncomplicated glaucoma was evaluated retrospectively in a consecutive series of 52 patients (mean follow-up, 18." | 3.68 | Initial 5-fluorouracil trabeculectomy in uncomplicated glaucoma. ( Liebmann, JM; Marmor, M; Nunez, J; Ritch, R; Wolner, B, 1991) |
| "The incidence of late-onset bleb-related endophthalmitis was evaluated retrospectively in 229 consecutive trabeculectomies performed with adjunctive 5-fluorouracil (5-FU) therapy." | 3.68 | Late bleb-related endophthalmitis after trabeculectomy with adjunctive 5-fluorouracil. ( Liebmann, JM; Marmor, M; Ritch, R; Sassani, JW; Speaker, M; Wolner, B, 1991) |
| "Nine patients (nine eyes) with iridocorneal endothelial (ICE) syndrome underwent trabeculectomy and received postoperative subconjunctival injections of 5-fluorouracil (5-FU) to enhance bleb formation (total 5-FU dose, 30-105 mg; mean, 53." | 3.68 | 5-Fluorouracil after trabeculectomy and the iridocorneal endothelial syndrome. ( Cristol, SM; Grajewski, AL; Parrish, RK; Wright, MM, 1991) |
| "In five glaucoma patients, a previous filtering surgery that was followed by sub-conjunctival injections of 5-Fluorouracil (5-FU) failed, due to filtering bleb scarring." | 3.68 | Filtering surgery with 5-fluorouracil: a second course. ( Ophir, A; Ticho, U, 1990) |
| "We reviewed the records of 12 eyes of ten adult patients with inflammatory glaucoma who underwent trabeculectomy with the adjuvant use of 5-fluorouracil between January 1986 and January 1989." | 3.68 | Trabeculectomy with 5-fluorouracil for adult inflammatory glaucoma. ( Jabs, DA; Jampel, HD; Quigley, HA, 1990) |
| "5-Fluorouracil (5-FU) was injected subconjunctivally after glaucoma filtering surgery in a pilot study of eyes with poor surgical prognoses." | 3.67 | 5-fluorouracil and glaucoma filtering surgery. II. A pilot study. ( Anderson, DR; Gressel, MG; Heuer, DK; Hodapp, E; Palmberg, PF; Parrish, RK, 1984) |
| "The antimetabolite 5-fluorouracil (5-FU) was used as adjunctive treatment in glaucomatous eyes with poor prognoses undergoing filtering surgery." | 3.67 | Adjusting the dose of 5-fluorouracil after filtration surgery to minimize side effects. ( Weinreb, RN, 1987) |
| "We show that a 40-mg total dose of subconjunctival 5-fluorouracil after glaucoma filtering surgery can provide a success rate comparable to that demonstrated in prior studies employing a higher dose." | 3.67 | Low-dose 5-fluorouracil and glaucoma filtration surgery. ( Rabowsky, JH; Ruderman, JM, 1989) |
| "5-fluorouracil is a useful new treatment modality in the difficult glaucoma filtering patient." | 3.67 | Polyvinyl alcohol membrane permeability characteristics of 5-fluorouracil. ( Hussain, AA; Maurin, MB; Milosovich, SM; Smith, TJ, 1988) |
| "A prospective, randomized, double-masked, and placebo-controlled study was performed to examine the effect of a localized and sustained delivery of 5-fluorouracil (5-FU) on the success of glaucoma filtration surgery in 18 rabbits." | 3.67 | Glaucoma filtration surgery in rabbits using bioerodible polymers and 5-fluorouracil. ( Anderson, PJ; de Kater, AW; Flores, RA; Hertzmark, E; Lee, DA; Leong, KW; Teekhasaenee, C, 1987) |
| "The antimetabolite 5-fluorouracil (5-FU) has been used to inhibit fibroblastic growth to increase the success rate in glaucoma filtration surgery." | 3.67 | Complications of subconjunctival 5-fluorouracil following glaucoma filtering surgery. ( Hersh, P; Kersten, D; Lee, DA; Melamed, S, 1987) |
| "The effect of 5-fluorouracil (5-FU) subconjunctival injection on the bleb formation and intraocular pressure (IOP) following trabeculectomy was studied in 18 glaucoma patients (20 eyes) with poor surgical prognosis." | 3.67 | 5-Fluorouracil for trabeculectomy in glaucoma. ( Kitazawa, Y; Nakano, Y; Shirato, S; Taniguchi, T; Yamamoto, T, 1987) |
| "We studied four patients who, having received postoperative 5-fluorouracil after glaucoma filtering operations, developed serious corneal complications." | 3.67 | Serious corneal complications of glaucoma filtering surgery with postoperative 5-fluorouracil. ( Driebe, WT; Heuer, DK; Knapp, A; Stern, GA, 1987) |
| "4), use of antiglaucoma medication, dosage of topical steroid postoperatively, and being operated on by a trainee surgeon (odds ratio, 2." | 2.72 | Effect of trabeculectomy on lens opacities in an East Asian population. ( Aung, T; Chew, PT; Devereux, JG; Foster, PJ; Gazzard, G; Husain, R; Khaw, PT; Oen, FT; Seah, SK, 2006) |
| "5-Fluorouracil and MMC were found to be equally safe and effective adjuncts to primary trabeculectomy in the short- and medium-term postoperative periods." | 2.69 | Trabeculectomy with intraoperative mitomycin C versus 5-fluorouracil. Prospective randomized clinical trial. ( Baerveldt, GS; Budenz, DL; Chen, PP; Cohen, JS; Greenfield, DS; Mehta, K; Moster, MR; Shaikh, NM; Shaikh, S; Singh, K; Tsai, JC, 2000) |
| "Last controlled intraocular pressure is lower in C group patients (13." | 2.68 | [Intra- and postoperative use of 5-fluorouracil in the surgical treatment of refractory glaucoma]. ( Apatachioaie, I; Brănişteanu, D; Chiseliţă, D; Poiata, I; Rusu, V; Tătăruş, C, 1997) |
| "Late postoperative complications are similar with the exception of an increased incidence of Tenon cyst formation in the MMC-treated eyes." | 2.68 | Mitomycin C versus 5-fluorouracil in high-risk glaucoma filtering surgery. Extended follow-up. ( Bergstrom, TJ; Higginbotham, EJ; Johnson, AT; Katz, GJ; Lichter, PR; Musch, DC; Skuta, GL, 1995) |
| "These include young patients, those with pigmentary glaucoma, secondary glaucoma, angle recession glaucoma, aphakic or pseudophakic glaucoma, and patients requiring reoperation." | 2.67 | Intraoperative mitomycin C in complicated glaucomas. ( Dogra, A; Kaur, J; Singh, G, 1993) |
| "Intraocular pressure was 20 mm Hg or lower in 24 eyes (96%) in the treatment group after mean follow-up of 17." | 2.67 | A randomized study of trabeculectomy and subconjunctival administration of fluorouracil in primary glaucomas. ( Ophir, A; Ticho, U, 1992) |
| "The risk of suprachoroidal hemorrhage was strongly associated with the level of the preoperative intraocular pressure." | 2.67 | Risk factors for suprachoroidal hemorrhage after filtering surgery. The Fluorouracil Filtering Surgery Study Group. ( , 1992) |
| "Raised intraocular pressure is a risk factor for glaucoma." | 2.52 | Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery. ( Cabourne, E; Clarke, JC; Evans, JR; Schlottmann, PG, 2015) |
| "In cases where such treatment fails, glaucoma-filtering surgery is considered, most commonly trabeculectomy surgery with variations in technique, for example, the type of conjunctival flap (fornix- or limbal-based)." | 2.52 | Fornix-based versus limbal-based conjunctival trabeculectomy flaps for glaucoma. ( Abdulaal, M; Al-Haddad, C; Al-Moujahed, A; Ervin, AM, 2015) |
| "The mean follow-up time after treatment for endophthalmitis was 6." | 2.41 | Delayed-onset bleb-associated endophthalmitis: clinical features and visual acuity outcomes. ( Budenz, DL; Flynn, HW; Scott, IU; Song, A, 2002) |
| "The use of antiscarring agents, particularly the antimetabolites 5-fluorouracil and mitomycin C, have revolutionized glaucoma surgery over the past decade." | 2.39 | Current techniques in wound healing modulation in glaucoma surgery. ( Khaw, PT; Migdal, CS, 1996) |
| "Mitomycin C seems to be a better treatment than 5 fluorouracil." | 2.38 | [Mitomycin C in glaucoma surgery]. ( Collignon-Brach, J, 1993) |
| "Filtering bleb encapsulation may, in some cases, be a severe complication following filtering surgery." | 2.38 | Encapsulated filtering bleb. A selective review--new deductions. ( Ophir, A, 1992) |
| " There was no significant adverse event for either group and no significant IOP difference in any of the observational periods between them (P=0." | 1.51 | Comparison of Efficacy and Safety of Bleb Needle Revision With and Without 5-Fluorouracil for Failing Trabeculectomy Bleb. ( Jeoung, JW; Kim, HJ; Kim, JS; Kim, YK; Na, KI; Park, KH, 2019) |
| "5-Fluorouracil (5-FU) has been well described for a failing trabeculectomy bleb, but not for aqueous shunts." | 1.46 | Use of subconjunctival injections of 5-fluorouracil to rescue and prolong intraocular pressure reduction for a failing Ahmed glaucoma implant. ( Kaplowitz, K; Khodadadeh, S; Lee, D; Tsai, JC; Wang, S, 2017) |
| "Intraocular pressure was 16 mmHg in the right and 36 mmHg in the left eye." | 1.40 | Iridocorneal endothelial syndrome. ( Akhtar, F; Ali, M; Saleem, AA, 2014) |
| "Mitomycin C was used in 12% and 0." | 1.35 | Australia and New Zealand survey of antimetabolite and steroid use in trabeculectomy surgery. ( Khaw, PT; Liu, L; Siriwardena, D, 2008) |
| "The area and the height of the bleb in the conjunctivae with radial incision (Ain and Hin, respectively) were compared with the area and the height of the bleb in the conjunctivae without radial incision (Ano and Hno, respectively)." | 1.35 | Restricted post-trabeculectomy bleb formation by conjunctival scarring. ( Inatani, M; Iwao, K; Ogata-Iwao, M; Takihara, Y; Tanihara, H, 2009) |
| "Others were encapsulated bleb 7." | 1.35 | Post-operative complication of trabeculectomy in Ibadan, Nigeria: outcome of 1-year follow-up. ( Ashaye, AO; Komolafe, OO, 2009) |
| "Twenty-four glaucoma filtering blebs in 24 eyes of 17 patients." | 1.33 | Comparison of two clinical Bleb grading systems. ( Ashraff, NN; Hall, RC; Purdie, G; Wells, AP, 2006) |
| " The consultants were asked to estimate the number of trabeculectomies they performed per year, how often they used 5-fluorouracil (5-FU) in primary and redo surgery, their usual method of administration of 5-FU, how often they used mitomycin (MMC) in primary and redo surgery, and their usual dosage regimen of MMC." | 1.32 | National survey of antimetabolite use in glaucoma surgery in the United Kingdom. ( Edmunds, B; Khaw, PT; Siriwardena, D; Wormald, RP, 2004) |
| "5-Fluorouracil was safe and improved trabeculectomy survival." | 1.31 | The efficacy and safety of intraoperative and/or postoperative 5-fluorouracil in trabeculectomy and phacotrabeculectomy. ( Goldberg, I; Mohsin, M; Singh, RP, 2001) |
| "Mitomycin C was administered intraoperatively in the dose of 0." | 1.31 | [Antimetabolites in glaucoma surgery--long-term results]. ( Ferková, S; Jakabovicová, E; Michalíková, L; Strmen, P, 2002) |
| "Intraocular pressures were lower in the group that received MMC compared to the 5-FU group, but not in the group that did not receive antimetabolites, at all time intervals measured (P < ." | 1.30 | Comparison of phacotrabeculectomy with 5-fluorouracil, mitomycin-C, and without antifibrotic agents. ( Budenz, DL; Gordon, J; Keates, EU; Piltz-Seymour, J; Pyfer, M; Singh, K, 1999) |
| "To study the effect of tissue plasminogen activator (t-PA) in combination with 5-fluorouracil (5-Fu) polyphase liposome on the prevention of scar formation in filtration surgery." | 1.30 | [The inhibitory effect of tissue plasminogen activator combined with 5-fluorouracil polyphase liposome on the scar formation in experimental filtration surgery]. ( Chen, R; Jing, M; Xi, S, 1997) |
| " The dose-response to 5-fluorouracil (5FU) and mitomycin C (MMC) was determined." | 1.30 | Collagen type I and III synthesis by Tenon's capsule fibroblasts in culture: individual patient characteristics and response to mitomycin C, 5-fluorouracil, and ascorbic acid. ( Gross, RL, 1999) |
| "14 eyes of 14 patients with medically untreatable glaucoma and extremely bad surgical prognosis because of young age, secondary glaucomas or following previous surgery were treated by means of goniotrephination with a scleral flap and a fornix-based conjunctival flap." | 1.29 | [5-fluorouracil in goniotrepanation with poor prognosis. Results of 1-year follow-up]. ( Grehn, F; Pfeiffer, N, 1993) |
| " In this study, 5-Fluorouracil (5-FU), a halogenated pyrimidine analogue and a potent anti-mitotic agent, was applied for seven days after trabeculectomy in eighteen complicated and unsuccessful filtering glaucomas, at a daily dosage of 5 mg in the form of 0." | 1.29 | The role of 5-fluorouracil in complicated glaucomas. ( Das, S; Jilani, FA; Khan, AM, 1993) |
| "Complications included suprachoroidal hemorrhage in 7 (14%) of 49 eyes and intraoperative vitreous hemorrhage in 2." | 1.29 | Holmium laser sclerectomy. Success and complications. ( Bellows, AR; Hutchinson, BT; Lytle, R; Puliafito, CA; Schuman, JS; Stinson, WG, 1993) |
| "5-Fluorouracil (5-FU) has been used to improve the outcome of trabeculectomy in high-risk cases, employing a postoperative regimen of subconjunctival injections." | 1.29 | Low-dose perioperative 5-fluorouracil in trabeculectomy. ( Hugkulstone, CE; Vernon, SA, 1996) |
| " In addition, toxic effects of 5-FU on existing fibroblasts, in rabbits and in vitro, were demonstrated." | 1.28 | Toxic effects of 5-fluorouracil on fibroblasts following trabeculectomy. ( Ophir, A; Ticho, U, 1992) |
| " Whether dose reduction will lead to reduced corneal toxicity in glaucoma filtration surgery following topical or subconjunctival dosing is an interesting therapeutic opportunity that remains to be determined." | 1.28 | Corneal penetration of 5-fluorouracil and its improvement by prodrug derivatization in the albino rabbit: implication in glaucoma filtration surgery. ( Bundgaard, H; Buur, A; Lee, VH; Wang, W, 1991) |
| "5-fluorouracil was injected subconjunctivally as an antiproliferative agent to prevent or decrease cell proliferation and scar formation." | 1.28 | External limbal sclerostomy with contact Nd:YAG laser versus surgical knife. ( Khoobehi, B; Oncel, M; Peyman, GA; Tawakol, ME, 1989) |
| "5-fluorouracil is an antimetabolite capable of inhibiting fibroblast proliferation." | 1.27 | 5-fluorouracil and glaucoma filtering surgery: I. An animal model. ( Folberg, R; Gressel, MG; Parrish, RK, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (8.95) | 18.7374 |
| 1990's | 151 (46.60) | 18.2507 |
| 2000's | 88 (27.16) | 29.6817 |
| 2010's | 48 (14.81) | 24.3611 |
| 2020's | 8 (2.47) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Mugheiry, TS | 1 |
| Clark, A | 1 |
| Broadway, DC | 1 |
| Lee, JY | 1 |
| Wu, J | 1 |
| Liu, Y | 1 |
| Saraswathy, S | 1 |
| Zhou, L | 1 |
| Bu, Q | 1 |
| Su, Y | 1 |
| Choi, D | 1 |
| Park, E | 1 |
| Strohmaier, CA | 1 |
| Weinreb, RN | 3 |
| Hong, YK | 1 |
| Pan, X | 1 |
| Huang, AS | 1 |
| Ioannou, N | 1 |
| Luo, J | 1 |
| Qin, M | 1 |
| Di Luca, M | 1 |
| Mathew, E | 1 |
| Tagalakis, AD | 1 |
| Lamprou, DA | 1 |
| Yu-Wai-Man, C | 1 |
| Halili, A | 1 |
| Kessel, L | 1 |
| Subhi, Y | 1 |
| Bach-Holm, D | 1 |
| Başer, EF | 1 |
| Seymenoğlu, RG | 1 |
| Inobhas, A | 1 |
| Chansangpetch, S | 1 |
| Manassakorn, A | 1 |
| Tantisevi, V | 1 |
| Rojanapongpun, P | 1 |
| Zhao, X | 1 |
| Liu, S | 1 |
| Han, Y | 4 |
| Wang, Y | 2 |
| Lin, Q | 1 |
| Kaplowitz, K | 2 |
| Khodadadeh, S | 1 |
| Wang, S | 1 |
| Lee, D | 1 |
| Tsai, JC | 3 |
| Lindemann, F | 1 |
| Plange, N | 2 |
| Kuerten, D | 1 |
| Schimitzek, H | 1 |
| Koutsonas, A | 2 |
| Quaranta, L | 1 |
| Katsanos, A | 1 |
| Legramandi, L | 1 |
| Riva, I | 1 |
| Zhang, C | 2 |
| Wang, J | 2 |
| Gao, H | 1 |
| Wang, X | 1 |
| Wu, M | 1 |
| Guo, B | 2 |
| Liu, C | 1 |
| Liu, W | 2 |
| Mercieca, K | 1 |
| Drury, B | 1 |
| Bhargava, A | 1 |
| Fenerty, C | 1 |
| Bhullar, GK | 1 |
| Skalicky, SE | 1 |
| Lew, HR | 1 |
| Pimentel, E | 1 |
| Schmidt, J | 1 |
| Elgin, U | 2 |
| Sen, E | 1 |
| Çolak, S | 1 |
| Yılmazbas, P | 1 |
| Koike, KJ | 1 |
| Chang, PT | 1 |
| Kumaran, A | 1 |
| Husain, R | 2 |
| Htoon, HM | 1 |
| Aung, T | 3 |
| Arnljots, TS | 1 |
| Kasina, R | 1 |
| Bykov, VJN | 1 |
| Economou, MA | 1 |
| Rabiolo, A | 1 |
| Marchese, A | 1 |
| Bettin, P | 1 |
| Monteduro, D | 1 |
| Galasso, M | 1 |
| Dolci, MP | 1 |
| Di Matteo, F | 1 |
| Fiori, M | 1 |
| Ciampi, C | 1 |
| Bandello, F | 1 |
| Swann, FB | 1 |
| Singh, S | 1 |
| Blake, D | 1 |
| John, V | 1 |
| Le, C | 1 |
| Fullerton, M | 1 |
| Margo, C | 1 |
| Zhang, Z | 1 |
| Muddasani, N | 1 |
| Wall, J | 1 |
| Satija, C | 1 |
| Greenberg, E | 1 |
| Mancera, N | 1 |
| Zurakowski, D | 2 |
| Ayyala, RS | 1 |
| Kim, JS | 1 |
| Kim, HJ | 1 |
| Na, KI | 1 |
| Kim, YK | 1 |
| Park, KH | 1 |
| Jeoung, JW | 1 |
| Lin, M | 1 |
| Alizadeh, R | 1 |
| Law, SK | 2 |
| Tatham, A | 1 |
| Sarodia, U | 1 |
| Karwatowski, W | 1 |
| Suh, W | 1 |
| Kee, C | 1 |
| Wu, X | 1 |
| Sun, Y | 1 |
| Zhang, Y | 1 |
| Zhang, H | 1 |
| Zhao, J | 1 |
| Suzuki, R | 2 |
| Susanna, R | 2 |
| Ozgonul, C | 1 |
| Mumcuoglu, T | 1 |
| Gunal, A | 1 |
| De Fendi, LI | 1 |
| Arruda, GV | 1 |
| Scott, IU | 2 |
| Paula, JS | 1 |
| Remky, A | 1 |
| De Moraes, CG | 1 |
| Alencar, LM | 1 |
| Ritch, R | 6 |
| Green, E | 1 |
| Wilkins, M | 1 |
| Bunce, C | 5 |
| Wormald, R | 4 |
| Saleem, AA | 1 |
| Ali, M | 1 |
| Akhtar, F | 1 |
| Menda, SA | 1 |
| Lowry, EA | 1 |
| Porco, TC | 2 |
| Stamper, RL | 5 |
| Rubin, MR | 1 |
| Zheng, L | 1 |
| Arvind, H | 1 |
| Wechsler, D | 1 |
| Cabourne, E | 1 |
| Clarke, JC | 1 |
| Schlottmann, PG | 1 |
| Evans, JR | 1 |
| Bi, XZ | 1 |
| Pan, WH | 1 |
| Yu, XP | 1 |
| Song, ZM | 1 |
| Ren, ZJ | 1 |
| Sun, M | 1 |
| Li, CH | 1 |
| Nan, KH | 1 |
| Al-Haddad, C | 1 |
| Abdulaal, M | 1 |
| Al-Moujahed, A | 1 |
| Ervin, AM | 1 |
| Amoozgar, B | 1 |
| Lin, SC | 3 |
| Kuo, J | 1 |
| Panarelli, JF | 1 |
| Vinod, K | 1 |
| Huang, G | 1 |
| Sidoti, PA | 2 |
| Cui, QN | 1 |
| Hsia, YC | 1 |
| Rose-Nussbaumer, J | 1 |
| Mehta, N | 1 |
| Naseri, A | 1 |
| Lorenz, K | 1 |
| Wasielica-Poslednik, J | 1 |
| Bell, K | 1 |
| Renieri, G | 1 |
| Keicher, A | 1 |
| Ruckes, C | 1 |
| Pfeiffer, N | 2 |
| Thieme, H | 1 |
| Minckler, DS | 3 |
| Francis, BA | 2 |
| Hodapp, EA | 1 |
| Jampel, HD | 4 |
| Samples, JR | 1 |
| Smith, SD | 1 |
| Singh, K | 5 |
| Alvarado, JA | 1 |
| Hollander, DA | 1 |
| Juster, RP | 2 |
| Lee, LC | 1 |
| Polak, MB | 1 |
| Valamanesh, F | 1 |
| Felt, O | 1 |
| Torriglia, A | 1 |
| Jeanny, JC | 1 |
| Bourges, JL | 1 |
| Rat, P | 1 |
| Thomas-Doyle, A | 1 |
| BenEzra, D | 1 |
| Gurny, R | 2 |
| Behar-Cohen, F | 1 |
| Taube, AB | 1 |
| Niemelä, P | 1 |
| Alm, A | 2 |
| Liu, L | 1 |
| Siriwardena, D | 2 |
| Khaw, PT | 15 |
| Palanca-Capistrano, AM | 2 |
| Hall, J | 1 |
| Cantor, LB | 2 |
| Morgan, L | 1 |
| Hoop, J | 2 |
| WuDunn, D | 2 |
| Zarkovic, A | 1 |
| Chow, K | 1 |
| Mora, JS | 2 |
| Memarzadeh, F | 1 |
| Varma, R | 1 |
| Lin, LT | 1 |
| Parikh, JG | 1 |
| Dustin, L | 1 |
| Alcaraz, A | 1 |
| Eliott, D | 1 |
| Iwao, K | 1 |
| Inatani, M | 1 |
| Ogata-Iwao, M | 1 |
| Takihara, Y | 1 |
| Tanihara, H | 1 |
| Anand, N | 4 |
| Khan, A | 1 |
| Kapasi, MS | 1 |
| Birt, CM | 1 |
| Hau, S | 1 |
| Barton, K | 2 |
| Kotecha, A | 1 |
| Spratt, A | 1 |
| Garway-Heath, DF | 1 |
| Viswanathan, A | 1 |
| Tay, E | 1 |
| Cree, IA | 1 |
| Hungerford, J | 1 |
| Franks, W | 1 |
| YANG, LQ | 1 |
| LAN, YQ | 1 |
| GUO, H | 1 |
| CHENG, LZ | 1 |
| FAN, JZ | 1 |
| CAI, X | 1 |
| ZHANG, LM | 1 |
| CHEN, RF | 1 |
| ZHOU, HS | 1 |
| Knape, RM | 1 |
| Smith, MF | 7 |
| Shafi, F | 1 |
| Agrawal, P | 1 |
| Holder, R | 1 |
| Sung, V | 1 |
| Narayanaswamy, AK | 1 |
| Lee, K | 1 |
| Zhen, M | 1 |
| Chua, J | 1 |
| Chai, SM | 1 |
| Boey, PY | 1 |
| Zheng, C | 1 |
| Venkatraman, S | 1 |
| Wong, TT | 2 |
| Salim, S | 1 |
| Chua, BE | 1 |
| Nguyen, DQ | 1 |
| Qin, Q | 1 |
| Ruddle, JB | 1 |
| Wells, AP | 2 |
| Niyadurupola, N | 1 |
| Gupta, V | 1 |
| Coote, MA | 1 |
| Crowston, JG | 1 |
| Roy, S | 1 |
| Mermoud, A | 2 |
| Congdon, NG | 1 |
| Krishnadas, R | 1 |
| Friedman, DS | 2 |
| Goggins, W | 1 |
| Ramakrishnan, R | 1 |
| Kader, MA | 1 |
| Gilbert, D | 1 |
| Tielsch, J | 1 |
| Quigley, HA | 3 |
| Simsek, T | 1 |
| Cankaya, AB | 1 |
| Hirji, N | 1 |
| Griffiths, M | 1 |
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| de Klerk, TA | 1 |
| Chaudhry, N | 1 |
| Moriarty, AP | 1 |
| Ceballos, EM | 1 |
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| Dickens, CJ | 4 |
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| Hoskins, HD | 5 |
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| Lakhani, V | 1 |
| Burnstein, A | 1 |
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| Lubomski, LH | 1 |
| Kempen, JH | 1 |
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| Robinson, KA | 1 |
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| Zeng, S | 1 |
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| Shields, MB | 2 |
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| Weinberger, D | 1 |
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| Parrish, RK | 11 |
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| Baudouin, C | 1 |
| Milivojević, M | 1 |
| Aleksić, P | 1 |
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| Latković, Z | 1 |
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| Ashaye, AO | 1 |
| Komolafe, OO | 1 |
| Rotchford, AP | 1 |
| King, AJ | 1 |
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| Heuer, DK | 7 |
| Gressel, MG | 5 |
| Hodapp, E | 3 |
| Palmberg, PF | 5 |
| Anderson, DR | 1 |
| Folberg, R | 2 |
| Ashton, P | 1 |
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| Pearson, PA | 1 |
| Jaffe, GJ | 1 |
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| Nussenblatt, RB | 1 |
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| Verin, P | 1 |
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| Bueche, MJ | 1 |
| Feuer, WJ | 2 |
| Grajewski, AL | 2 |
| Trope, GE | 1 |
| Cheng, YL | 1 |
| Sheardown, H | 1 |
| Liu, GS | 1 |
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| Heathcote, JG | 1 |
| Rootman, DS | 1 |
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| Liu, X | 1 |
| Lee, DA | 5 |
| Thomas, R | 1 |
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| Sen, S | 1 |
| Nuyts, RM | 1 |
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| Geijssen, HC | 1 |
| Grossniklaus, HE | 1 |
| Greve, EL | 1 |
| Lanigan, L | 1 |
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| Baez, KA | 2 |
| Hitchings, RA | 3 |
| Reinhard, T | 1 |
| Klüppel, M | 1 |
| Sundmacher, R | 1 |
| Drake, MV | 3 |
| Oh, Y | 1 |
| Katz, LJ | 3 |
| Spaeth, GL | 5 |
| Wilson, RP | 1 |
| Cunliffe, IA | 1 |
| Longstaff, S | 1 |
| Shin, DH | 2 |
| Collignon-Brach, J | 1 |
| Rozsíval, P | 3 |
| Liehneová, I | 2 |
| Sherwood, MB | 6 |
| Miller, MH | 1 |
| Rice, NS | 2 |
| Doyle, JW | 5 |
| McGrory, S | 1 |
| Skuta, GL | 5 |
| Bluestein, EC | 1 |
| Stewart, WC | 2 |
| Hurvitz, LM | 1 |
| Singh, G | 1 |
| Kaur, J | 1 |
| Dogra, A | 1 |
| Khan, AM | 1 |
| Jilani, FA | 1 |
| Das, S | 1 |
| Ophir, A | 11 |
| Ticho, U | 10 |
| Langseth, FG | 1 |
| Schuman, JS | 1 |
| Stinson, WG | 1 |
| Hutchinson, BT | 1 |
| Bellows, AR | 1 |
| Puliafito, CA | 1 |
| Lytle, R | 1 |
| Agarwal, HC | 1 |
| Sandramouli, S | 1 |
| Sihota, R | 1 |
| Sood, NN | 1 |
| Stilma, JS | 1 |
| Xiong, XL | 1 |
| Grierson, I | 3 |
| Schultz, G | 1 |
| McGorray, S | 3 |
| Rockwood, EJ | 5 |
| Takahashi, H | 1 |
| Palcic, B | 1 |
| Damji, KF | 1 |
| Rootman, J | 1 |
| Drance, SM | 1 |
| Kawase, K | 2 |
| Nishimura, K | 1 |
| Yamamoto, T | 3 |
| Jikihara, S | 1 |
| Kitazawa, Y | 4 |
| White, TC | 1 |
| Shoji, N | 1 |
| Araie, M | 2 |
| Shirato, S | 3 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Macular Thickness in Patients With Glaucoma in Use of Topical Prostaglandin Analogue Undergoing Trabeculectomy With Mitomycin C[NCT06000280] | 37 participants (Actual) | Interventional | 2021-01-04 | Completed | |||
| Early Transconjunctival Needling Revision With 5-fluorouracil Versus Medical Treatment in Encapsulated Blebs: a 12-month Prospective Study[NCT01887223] | Phase 2 | 40 participants (Actual) | Interventional | 2010-05-31 | Completed | ||
| Clinical Efficacy and Safety of Minimally Invasive Glaucoma Surgery on Chinese Primary Angle Closure Glaucoma[NCT02964676] | 246 participants (Anticipated) | Interventional | 2017-01-31 | Not yet recruiting | |||
| Efficacy and Safety of Trabeculectomy With Subconjunctival Bevacizumab Versus Trabeculectomy With Mitomycin C.[NCT01310764] | 36 participants (Actual) | Interventional | 2009-04-30 | Completed | |||
| Intermediate Term Outcomes of Intraoperative 5-Fluorouracil Versus Mitomycin c in Trabeculectomy Surgery.[NCT00346489] | Phase 4 | 70 participants | Interventional | 2004-09-30 | Completed | ||
| Re-Trabeculectomy Versus Ahmed Glaucoma Valve Implantation in Secondary Surgical Management of Patients With Refractory Primary Open Angle Glaucoma: a Three-year Comparative Study[NCT01633775] | 100 participants (Actual) | Observational | 2007-12-31 | Completed | |||
| Intraocular Pressure Control Following One Site Versus Two Site Combined Phacoemulsification/IOL And Trabeculectomy[NCT00695747] | 95 participants (Actual) | Interventional | 1998-01-31 | Completed | |||
| [NCT00000122] | Phase 3 | 0 participants | Interventional | 1985-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
42 reviews available for fluorouracil and Glaucoma
| Article | Year |
|---|---|
Needling after trabeculectomy - does augmentation by anti-metabolites provide better outcomes and is Mitomycin C better than 5-Fluoruracil? A systematic review with network meta-analyses.
Topics: Fluorouracil; Glaucoma; Humans; Immunosuppressive Agents; Intraocular Pressure; Mitomycin; Network M | 2020 |
Is mytomicyn better than 5-fluorouracil as antimetabolite in trabeculectomy for glaucoma?
Topics: Antimetabolites; Cicatrix; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Mitomycin; Randomiz | 2018 |
Trabeculectomy: A Brief History and Review of Current Trends.
Topics: Angiogenesis Inhibitors; Fluorouracil; Glaucoma; History, 20th Century; History, 21st Century; Human | 2018 |
Mitomycin C versus 5-fluorouracil as an adjunctive treatment for trabeculectomy: a meta-analysis of randomized clinical trials.
Topics: Alkylating Agents; Antimetabolites; Chemotherapy, Adjuvant; Epithelium, Corneal; Fluorouracil; Glauc | 2013 |
5-Fluorouracil for glaucoma surgery.
Topics: Antimetabolites; Cicatrix; Fluorouracil; Glaucoma; Humans; Randomized Controlled Trials as Topic; Tr | 2014 |
Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery.
Topics: Antimetabolites; Chemotherapy, Adjuvant; Cicatrix; Fluorouracil; Glaucoma; Humans; Intraocular Press | 2015 |
Fornix-based versus limbal-based conjunctival trabeculectomy flaps for glaucoma.
Topics: Antihypertensive Agents; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Limbus Corneae; Mitom | 2015 |
Corneal complications of glaucoma surgery.
Topics: Corneal Diseases; Corneal Transplantation; Fluorouracil; Glaucoma; Glaucoma Drainage Implants; Graft | 2009 |
Current variations of glaucoma filtration surgery.
Topics: Alkylating Agents; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Mitomycin; Surgical Flaps; | 2012 |
Deep sclerectomy.
Topics: Conjunctiva; Fibrosis; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Immunosuppressive Agents; | 2012 |
Effect of technique on intraocular pressure after combined cataract and glaucoma surgery: An evidence-based review.
Topics: Antimetabolites, Antineoplastic; Cataract; Cataract Extraction; Evidence-Based Medicine; Fluorouraci | 2002 |
[Modulation of wound healing in filtration surgery for glaucoma].
Topics: Adolescent; Adult; Age Factors; Alkylating Agents; Animals; Antimetabolites; Child; Filtering Surger | 2003 |
Glaucoma-filtering bleb infections.
Topics: Anti-Bacterial Agents; Drug Administration Schedule; Endophthalmitis; Fibrosis; Filtering Surgery; F | 2003 |
Update on antifibrotic use in glaucoma surgery, including use in trabeculectomy and glaucoma drainage implants and combined cataract and glaucoma surgery.
Topics: Antimetabolites, Antineoplastic; Cataract Extraction; Fibrosis; Fluorouracil; Glaucoma; Glaucoma Dra | 2004 |
[Pharmacological methods improving the effectiveness of filtering procedures].
Topics: Antibiotics, Antineoplastic; Antibodies; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Cy | 2004 |
Wound healing after glaucoma surgery: how to manage it?
Topics: Adult; Aged; Antimetabolites; Filtering Surgery; Fluorouracil; Glaucoma; Guidelines as Topic; Humans | 2005 |
[Postoperative care after glaucoma filtration surgery].
Topics: Administration, Topical; Cicatrix; Filtering Surgery; Fluorouracil; Glaucoma; Humans; Immunosuppress | 2006 |
[Wound healing modulation in glaucoma surgery].
Topics: Adult; Animals; Cataract Extraction; Child; Cicatrix; Eye Diseases; Filtering Surgery; Fluorouracil; | 2007 |
Review: implants.
Topics: Animals; Cyclosporine; Cytomegalovirus Retinitis; Delayed-Action Preparations; Drug Implants; Filter | 1994 |
[Trabeculectomy with mitomycin C. Study apropos of 30 cases].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Female; Fluorouracil; Follow-Up | 1995 |
Antifibrosis agents and glaucoma surgery.
Topics: Animals; Conjunctiva; Fibrosis; Filtering Surgery; Fluorouracil; Glaucoma; Humans; Mitomycin | 1994 |
[Mitomycin C in glaucoma surgery].
Topics: Adult; Aged; Aged, 80 and over; Cicatrix; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Midd | 1993 |
Antifibrotic agents in glaucoma filtering surgery.
Topics: Animals; Cataract Extraction; Fluorouracil; Glaucoma; Humans; Mitomycin; Rabbits; Sclerostomy; Wound | 1993 |
Wound healing modulation in glaucoma filtration surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Fluorouracil; Glaucoma; Humans; Intraocular | 1993 |
Trabeculectomy with intraoperative sponge 5-fluorouracil.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Chemotherapy, Adjuvant; Child; Child, P | 1996 |
[Filtering glaucoma operations. Can growth factor blockers replace antimetabolites?].
Topics: Antimetabolites, Antineoplastic; Cell Division; Combined Modality Therapy; Filtering Surgery; Fluoro | 1997 |
Basic science and clinical aspects of wound healing in glaucoma filtering surgery.
Topics: Culture Techniques; Fibroblasts; Fibrosis; Filtering Surgery; Fluorouracil; Glaucoma; Humans; Mitomy | 1998 |
Combined glaucoma filtration surgery and phacoemulsification.
Topics: Cataract Extraction; Filtration; Fluorouracil; Glaucoma; Humans; Lens, Crystalline; Lenses, Intraocu | 1992 |
Management of coincident glaucoma and cataract.
Topics: Cataract; Cataract Extraction; Exfoliation Syndrome; Fluorouracil; Glaucoma; Humans; Lenses, Intraoc | 1995 |
Surgical consequences in coexisting cataract and glaucoma.
Topics: Cataract; Cataract Extraction; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Lenses, Intraoc | 1995 |
Current techniques in wound healing modulation in glaucoma surgery.
Topics: Animals; Antimetabolites; Cataract Extraction; Cicatrix; Filtering Surgery; Fluorouracil; Glaucoma; | 1996 |
A major review of antimetabolites in glaucoma therapy.
Topics: Antimetabolites; Cytarabine; Filtering Surgery; Fluorouracil; Glaucoma; Humans; Mitomycin; Ophthalmi | 1999 |
Glaucoma surgery: are there new perspectives in perioperative pharmacology?
Topics: Antimetabolites; Chemotherapy, Adjuvant; Fibrinolytic Agents; Filtering Surgery; Fluorouracil; Glauc | 1999 |
[The use of antimetabolites in the treatment of glaucoma].
Topics: Antimetabolites; Chemotherapy, Adjuvant; Fluorouracil; Glaucoma; Humans; Intraoperative Care; Mitomy | 1999 |
Post-operative 5-fluorouracil for glaucoma surgery.
Topics: Antimetabolites; Fluorouracil; Glaucoma; Humans; Trabeculectomy | 2000 |
The use of antimetabolites with trabeculectomy: a critical appraisal.
Topics: Antimetabolites; Combined Modality Therapy; Delivery of Health Care; Fluorouracil; Glaucoma; Humans; | 2001 |
Post-operative 5-Fluorouracil for glaucoma surgery.
Topics: Antimetabolites; Cicatrix; Fluorouracil; Glaucoma; Humans; Trabeculectomy; Wound Healing | 2001 |
Advances in glaucoma surgery: evolution of antimetabolite adjunctive therapy.
Topics: Antimetabolites; Chemotherapy, Adjuvant; Fluorouracil; Glaucoma; Humans; Intraoperative Period; Mito | 2001 |
Delayed-onset bleb-associated endophthalmitis: clinical features and visual acuity outcomes.
Topics: Adult; Aged; Aged, 80 and over; Anterior Chamber; Bacteria; Endophthalmitis; Eye Infections, Bacteri | 2002 |
Encapsulated filtering bleb. A selective review--new deductions.
Topics: Animals; Blister; Cicatrix; Conjunctival Diseases; Fibroblasts; Fluorouracil; Glaucoma; Humans; Post | 1992 |
Surgical management of the secondary glaucomas: Part I.
Topics: Ciliary Body; Cryosurgery; Filtration; Fluorouracil; Glaucoma; Humans; Laser Therapy; Light Coagulat | 1987 |
[Prevention of eye scarring by 5-fluorouracil].
Topics: Animals; Cicatrix; Disease Models, Animal; Eye; Fluorouracil; Glaucoma; Humans; Postoperative Compli | 1987 |
46 trials available for fluorouracil and Glaucoma
| Article | Year |
|---|---|
Fluorouracil Filtering Surgery Study One-Year Follow-up.
Topics: Aged; Conjunctiva; Dose-Response Relationship, Drug; Female; Filtering Surgery; Fluorouracil; Follow | 2018 |
Longitudinal Changes in Bleb Height, Vascularity, and Conjunctival Microcysts After Trabeculectomy.
Topics: Aged; Blister; Combined Modality Therapy; Conjunctiva; Conjunctival Diseases; Cysts; Female; Fluorou | 2018 |
The effect of bevacizumab on the outcome of trabeculectomy with 5-Fluorouracil.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Bevaciz | 2013 |
Early transconjunctival needling revision with 5-fluorouracil versus medical treatment in encapsulated blebs: a 12-month prospective study.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Blister; Conjunctiva; Female; Fluorouracil; Glaucom | 2013 |
Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolamide and dexamethasone eye drops and assessment of the clinical outcome of trabeculectomy in glaucoma.
Topics: Acetazolamide; Aged; Antihypertensive Agents; Dexamethasone; Drug Combinations; Female; Fluorouracil | 2017 |
Long-term outcomes of intraoperative 5-fluorouracil versus intraoperative mitomycin C in primary trabeculectomy surgery.
Topics: Administration, Topical; Alkylating Agents; Antihypertensive Agents; Antimetabolites; Combined Modal | 2009 |
Optic disc and visual field changes after trabeculectomy.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Combined Modality Therapy; Disease Progression; Dou | 2009 |
Randomized, controlled trial of a sustained delivery formulation of 5-fluorouracil for the treatment of failing blebs.
Topics: Aged; Aqueous Humor; Conjunctiva; Delayed-Action Preparations; Female; Fluorouracil; Glaucoma; Human | 2012 |
Bleb vascularity following post-trabeculectomy subconjunctival bevacizumab: a pilot study.
Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antimetabolites; Bevacizumab; Conj | 2012 |
A study of initial therapy for glaucoma in southern India: India Glaucoma Outcomes and Treatment (INGOT) Study.
Topics: Aged; Antihypertensive Agents; Antimetabolites, Antineoplastic; Brimonidine Tartrate; Drug Combinati | 2012 |
Comparison of needle revision with subconjunctival bevacizumab and 5-fluorouracil injection of failed trabeculectomy blebs.
Topics: Antibodies, Monoclonal, Humanized; Bevacizumab; Conjunctiva; Female; Fluorouracil; Glaucoma; Humans; | 2012 |
A prospective randomized trial comparing intraoperative 5-fluorouracil vs mitomycin C in primary trabeculectomy.
Topics: Antimetabolites; Double-Blind Method; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Intraope | 2002 |
[Intra- and postoperative use of 5-fluorouracil in the surgical treatment of refractory glaucoma].
Topics: Antimetabolites; Conjunctiva; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Injections; Intraoc | 1997 |
Comparison of 1-site versus 2-site phacotrabeculectomy.
Topics: Antihypertensive Agents; Case-Control Studies; Cataract; Fluorouracil; Follow-Up Studies; Glaucoma; | 2006 |
Effect of trabeculectomy on lens opacities in an East Asian population.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Cataract; Combined Modality Therapy; Disease Progre | 2006 |
[A comparative study of homoharringtonine with 5-fluorouracil in filtering surgery].
Topics: Adolescent; Adult; Double-Blind Method; Female; Fluorouracil; Glaucoma; Harringtonines; Homoharringt | 1994 |
Update of the subconjunctival THC:YAG (holmium) laser sclerostomy ab externo clinical trial: 30-month report.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Female; Fluorouracil; Follow-Up Studies; Glaucoma | 1994 |
Risk factors for the development of encapsulated filtering blebs. The role of surgical glove powder and 5-fluorouracil.
Topics: Adult; Aged; Aged, 80 and over; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Gloves, Surgical; | 1994 |
Intraoperative mitomycin C in complicated glaucomas.
Topics: Adult; Age Factors; Aged; Aphakia; Drug Evaluation; Female; Fluorouracil; Glaucoma; Glaucoma, Open-A | 1993 |
Three-year follow-up of the Fluorouracil Filtering Surgery Study.
Topics: Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Postoperative Care; Surviva | 1993 |
[A five-year follow-up of the effect of postoperative 5-fluorouracil subconjunctival injections on the surgical outcome of trabeculectomy].
Topics: Adult; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Injections; Intraocul | 1993 |
Five-year follow-up of the Fluorouracil Filtering Surgery Study. The Fluorouracil Filtering Surgery Study Group.
Topics: Cataract Extraction; Chemotherapy, Adjuvant; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Immu | 1996 |
Results of intraoperative 5-fluorouracil in patients undergoing trabeculectomy--pilot trial.
Topics: Adolescent; Adult; Aged; Antimetabolites; Chemotherapy, Adjuvant; Conjunctiva; Female; Fluorouracil; | 1996 |
Temporal corneal phacoemulsification combined with superior trabeculectomy: a controlled study.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Cataract; Cornea; Female; Fluorouracil; Glaucoma; Hum | 1996 |
Mitomycin C versus 5-fluorouracil in high-risk glaucoma filtering surgery. Extended follow-up.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Female; Filter | 1995 |
Trabeculectomy with intraoperative 5-fluorouracil vs mitomycin C.
Topics: Antimetabolites; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Intraoperative Care; | 1997 |
Oral prednisone in guarded filtration procedures supplemented with antimetabolites.
Topics: Administration, Oral; Aged; Chemotherapy, Adjuvant; Double-Blind Method; Female; Filtering Surgery; | 1999 |
A randomized phase II trial of interferon-alpha2b versus 5-fluorouracil after trabeculectomy.
Topics: Adult; Aged; Aged, 80 and over; Cataract; Cataract Extraction; Connective Tissue; Double-Blind Metho | 1999 |
Combined cataract and glaucoma surgery: trabeculectomy versus endoscopic laser cycloablation.
Topics: Cataract; Ciliary Body; Endoscopy; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intrao | 1999 |
Low-dose 5-fluorouracil trabeculectomy as initial surgery in uncomplicated glaucoma: long-term followup.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Female; Fluorouracil; Follow-Up | 2000 |
Trabeculectomy with intraoperative mitomycin C versus 5-fluorouracil. Prospective randomized clinical trial.
Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Drug Evaluation; Female; Fluorouracil | 2000 |
Randomized, controlled study of low-dose 5-fluorouracil in primary trabeculectomy.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Chemotherapy, Adjuvant; Conjunctiva; Drug Evaluatio | 2000 |
Prognosis and risk factors for early postoperative wound leaks after trabeculectomy with and without 5-fluorouracil.
Topics: Antimetabolites; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Injections; | 2001 |
Single intraoperative application of 5-Fluorouracil versus placebo in low-risk trabeculectomy surgery: a randomized trial.
Topics: Aged; Antimetabolites; Chemotherapy, Adjuvant; Conjunctiva; Double-Blind Method; Female; Fluorouraci | 2001 |
Long-term results of trabeculectomy with collagen sponge implant containing low-dose antimetabolite.
Topics: Adult; Aged; Biological Dressings; Bleomycin; Collagen; Drug Implants; Female; Fluorouracil; Glaucom | 1992 |
A randomized study of trabeculectomy and subconjunctival administration of fluorouracil in primary glaucomas.
Topics: Aged; Aged, 80 and over; Conjunctiva; Female; Fluorouracil; Glaucoma; Humans; Injections; Intraocula | 1992 |
Intraoperative mitomycin versus postoperative 5-fluorouracil in high-risk glaucoma filtering surgery.
Topics: Adult; Aged; Aged, 80 and over; Corneal Diseases; Epithelium; Female; Fluorouracil; Glaucoma; Humans | 1992 |
Risk factors for suprachoroidal hemorrhage after filtering surgery. The Fluorouracil Filtering Surgery Study Group.
Topics: Aged; Cataract Extraction; Choroid Hemorrhage; Fluorouracil; Glaucoma; Humans; Incidence; Intraocula | 1992 |
Trabeculectomy with mitomycin. A comparative study with fluorouracil.
Topics: Adult; Aged; Cicatrix; Combined Modality Therapy; Female; Fluorouracil; Glaucoma; Humans; Intraocula | 1991 |
The use of 5-fluorouracil in patients following combined trabeculectomy and cataract extraction.
Topics: Aged; Aged, 80 and over; Cataract Extraction; Combined Modality Therapy; Female; Fluorouracil; Glauc | 1991 |
Fluorouracil Filtering Surgery Study one-year follow-up. The Fluorouracil Filtering Surgery Study Group.
Topics: Adult; Aged; Bias; Chi-Square Distribution; Data Interpretation, Statistical; Female; Fluorouracil; | 1989 |
Fluorouracil Filtering Surgery Study one-year follow-up. The Fluorouracil Filtering Surgery Study Group.
Topics: Adult; Aged; Bias; Chi-Square Distribution; Data Interpretation, Statistical; Female; Fluorouracil; | 1989 |
Fluorouracil Filtering Surgery Study one-year follow-up. The Fluorouracil Filtering Surgery Study Group.
Topics: Adult; Aged; Bias; Chi-Square Distribution; Data Interpretation, Statistical; Female; Fluorouracil; | 1989 |
Fluorouracil Filtering Surgery Study one-year follow-up. The Fluorouracil Filtering Surgery Study Group.
Topics: Adult; Aged; Bias; Chi-Square Distribution; Data Interpretation, Statistical; Female; Fluorouracil; | 1989 |
Effect of postoperative subconjunctival 5-fluorouracil injections on the surgical outcome of trabeculectomy in the Japanese.
Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Conjunctiva; Fluorouracil; Follow-Up Studi | 1989 |
The use of bioerodible polymers and 5-fluorouracil in glaucoma filtration surgery.
Topics: Animals; Clinical Trials as Topic; Disease Models, Animal; Double-Blind Method; Fluorouracil; Glauco | 1988 |
A prospective, randomized study of 5-fluorouracil and filtration surgery.
Topics: Adolescent; Adult; Aged; Child; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Male; | 1987 |
Participants in clinical trial in glaucoma needed.
Topics: Clinical Trials as Topic; Conjunctiva; Fluorouracil; Glaucoma; Humans; Postoperative Care | 1986 |
A randomized study of 5-fluorouracil and filtration surgery.
Topics: Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Postoperative Compl | 1987 |
236 other studies available for fluorouracil and Glaucoma
| Article | Year |
|---|---|
The Norwich trabeculectomy study: risk factor analysis for the development of adverse, thin cystic blebs.
Topics: Antimetabolites; Conjunctiva; Factor Analysis, Statistical; Fluorouracil; Glaucoma; Humans; Intraocu | 2022 |
Subconjunctival Lymphatics Respond to VEGFC and Anti-Metabolites in Rabbit and Mouse Eyes.
Topics: Animals; Antimetabolites; Conjunctiva; Dextrans; Fluorouracil; Glaucoma; Intraocular Pressure; Mice; | 2022 |
3D-printed long-acting 5-fluorouracil implant to prevent conjunctival fibrosis in glaucoma.
Topics: Chitosan; Delayed-Action Preparations; Fluorouracil; Glaucoma; Humans; Printing, Three-Dimensional | 2023 |
Results of fluorouracil-augmented Xen45 implantation in primary open-angle and pseudoexfoliation glaucoma.
Topics: Aged; Fluorouracil; Glaucoma; Glaucoma Drainage Implants; Glaucoma, Open-Angle; Humans; Intraocular | 2021 |
Effect of oral statin use on mitomycin-C augmented trabeculectomy outcomes.
Topics: Administration, Oral; Adult; Aged; Antimetabolites; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2021 |
Preparation of 5-fluorouracil loaded chitosan microtube via in situ precipitation for glaucoma drainage device application: in vitro and in vivo investigation.
Topics: Chitosan; Fluorouracil; Glaucoma; Glaucoma Drainage Implants; Humans; Intraocular Pressure | 2021 |
Use of subconjunctival injections of 5-fluorouracil to rescue and prolong intraocular pressure reduction for a failing Ahmed glaucoma implant.
Topics: Aged; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Glaucoma Drainage Implants; Hu | 2017 |
Three-Year Follow-Up of Trabeculectomy with 5-Fluorouracil.
Topics: Adult; Aged; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Germany; Glaucoma; Humans; Immuno | 2017 |
Subconjunctival injections of 5-fluorouracil for failing Ahmed glaucoma implants.
Topics: Conjunctiva; Fluorouracil; Glaucoma; Glaucoma Drainage Implants; Humans; Injections; Intraocular Pre | 2017 |
Use of subconjunctival injections of 5-fluorouracil to rescue and prolong intraocular pressure reduction for a failing Ahmed glaucoma implant.
Topics: Fluorouracil; Glaucoma; Glaucoma Drainage Implants; Humans; Injections; Intraocular Pressure; Ocular | 2017 |
Retrospective observation on trabeculectomy of primary congenital glaucoma by applying biological amniotic membranes soaked with 5-fluorouracil.
Topics: Adolescent; Amnion; Antimetabolites, Antineoplastic; Biological Dressings; Child; Child, Preschool; | 2018 |
Trabeculectomy bleb needling and antimetabolite administration practices in the UK: a glaucoma specialist national survey.
Topics: Antimetabolites; Cross-Sectional Studies; Dose-Response Relationship, Drug; Fluorouracil; Glaucoma; | 2018 |
Bilateral Scheie's procedure with Ophthalmic Viscoelastic Device and 5-Fluorouracil.
Topics: Female; Fluorouracil; Glaucoma; Glaucoma Drainage Implants; Humans; Immunosuppressive Agents; Inject | 2019 |
Initial trabeculectomy with 5-fluorouracil with or without subconjunctival bevacizumab in the management of pseudoexfoliation glaucoma.
Topics: Aged; Angiogenesis Inhibitors; Antihypertensive Agents; Bevacizumab; Exfoliation Syndrome; Female; F | 2019 |
Needling With 5-Fluorouracil (5-FU) After XEN Gel Stent Implantation: 6-Month Outcomes.
Topics: Aged; Aged, 80 and over; Exfoliation Syndrome; Female; Fluorouracil; Gels; Glaucoma; Glaucoma Draina | 2018 |
Needle revision outcomes after glaucoma filtering surgery: survival analysis and predictive factors.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Combined Modality Therapy; Female; Fluorouracil; Gl | 2020 |
Effect of 2 Novel Sustained-release Drug Release Systems on Bleb Fibrosis: An In Vivo Trabeculectomy Study in a Rabbit Model.
Topics: Absorbable Implants; Animals; Drug Delivery Systems; Drug Implants; Drug Liberation; Endophthalmitis | 2019 |
Comparison of Efficacy and Safety of Bleb Needle Revision With and Without 5-Fluorouracil for Failing Trabeculectomy Bleb.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Conjunctiva; Female; Fluorouracil; Glaucoma; Humans | 2019 |
Outcomes of Combined Ahmed Glaucoma Valve and Trabeculectomy Revision With Adjunctive Antimetabolite.
Topics: Aged; Aged, 80 and over; Antimetabolites; Case-Control Studies; Chemotherapy, Adjuvant; Combined Mod | 2019 |
5-Fluorouracil augmented needle revision of trabeculectomy: does the location of outflow resistance make a difference?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Child; Conjunctiva; Fem | 2013 |
Impact of application of bio-amniotic membrane immersed in 5-fluorouracil solution in trabeculectomy on rabbit retina.
Topics: Amnion; Animals; Chromatography, High Pressure Liquid; Female; Fluorouracil; Glaucoma; Immunosuppres | 2013 |
The effect of bevacizumab on wound healing modulation in an experimental trabeculectomy model.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Bevacizumab; Disease Models, An | 2014 |
[Long-term results after trabeculectomy with 5-fluorouracil].
Topics: Aged; Combined Modality Therapy; Female; Fluorouracil; Glaucoma; Humans; Immunosuppressive Agents; I | 2014 |
Nd:YAG laser goniopuncture for late bleb failure after trabeculectomy with adjunctive mitomycin C.
Topics: Aged; Alkylating Agents; Female; Fluorouracil; Glaucoma; Gonioscopy; Humans; Intraocular Pressure; L | 2014 |
Iridocorneal endothelial syndrome.
Topics: Adult; Fluorouracil; Glaucoma; Glaucoma, Angle-Closure; Gonioscopy; Humans; Intraocular Pressure; Ir | 2014 |
Ex-PRESS outcomes using mitomycin-C, Ologen alone, Ologen with 5-fluorouracil.
Topics: Aged; Alkylating Agents; Anthracenes; Antihypertensive Agents; Collagen; Combined Modality Therapy; | 2015 |
Outcomes: Trabeculectomy Bleb Needle Revision With 5-Fluorouracil.
Topics: Aged; Antihypertensive Agents; Antimetabolites; Combined Modality Therapy; Female; Fluorouracil; Fol | 2016 |
Application of 5-Fluorouracil-Polycaprolactone Sustained-Release Film in Ahmed Glaucoma Valve Implantation Inhibits Postoperative Bleb Scarring in Rabbit Eyes.
Topics: Animals; Anterior Eye Segment; Cicatrix; Delayed-Action Preparations; Fluorouracil; Glaucoma; Glauco | 2015 |
A role for antimetabolites in glaucoma tube surgery: current evidence and future directions.
Topics: Animals; Antimetabolites; Fibrosis; Fluorouracil; Glaucoma; Humans; Mitomycin; Trabeculectomy | 2016 |
Transconjunctival Revision With Mitomycin-C Following Failed Trabeculectomy.
Topics: Aged; Aged, 80 and over; Alkylating Agents; Combined Modality Therapy; Conjunctiva; Female; Fluorour | 2016 |
Effect of mitomycin c and 5-flurouracil adjuvant therapy on the outcomes of Ahmed glaucoma valve implantation.
Topics: Administration, Topical; Aged; Antibiotics, Antineoplastic; Dose-Response Relationship, Drug; Drug T | 2017 |
Aqueous shunts in glaucoma: a report by the American Academy of Ophthalmology.
Topics: Academies and Institutes; Alkylating Agents; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; | 2008 |
Ahmed valve implantation with adjunctive mitomycin C and 5-fluorouracil: long-term outcomes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alkylating Agents; Cataract Extraction; Combined Modalit | 2008 |
Controlled delivery of 5-chlorouracil using poly(ortho esters) in filtering surgery for glaucoma.
Topics: Animals; Antimitotic Agents; Apoptosis; Blister; Cell Death; Cell Proliferation; Cell Survival; Cell | 2008 |
Trabeculectomy with an active postoperative regimen: results and resource utilization.
Topics: Aged; Conjunctiva; Female; Fluorouracil; Glaucoma; Glaucoma, Open-Angle; Humans; Injections; Intraoc | 2009 |
A modified technique of Ahmed glaucoma valve implantation with adjunctive use of antifibrotic agents.
Topics: Alkylating Agents; Combined Modality Therapy; Fibrosis; Fluorouracil; Glaucoma; Glaucoma Drainage Im | 2008 |
Australia and New Zealand survey of antimetabolite and steroid use in trabeculectomy surgery.
Topics: Antimetabolites; Australia; Cross-Sectional Studies; Fluorouracil; Glaucoma; Glucocorticoids; Health | 2008 |
Comparison of 90-s versus 5-min intraoperative 5-fluorouracil in trabeculectomy.
Topics: Aged; Antihypertensive Agents; Antimetabolites; Blister; Cicatrix; Female; Fluorouracil; Follow-Up S | 2010 |
Postoperative use of bevacizumab as an antifibrotic agent in glaucoma filtration surgery in the rabbit.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimet | 2009 |
Restricted post-trabeculectomy bleb formation by conjunctival scarring.
Topics: Antimetabolites; Blister; Cicatrix; Combined Modality Therapy; Conjunctiva; Conjunctival Diseases; C | 2009 |
Long-term outcomes of needle revision of trabeculectomy blebs with mitomycin C and 5-fluorouracil: a comparative safety and efficacy report.
Topics: Aged; Alkylating Agents; Antihypertensive Agents; Combined Modality Therapy; Female; Fluorouracil; F | 2009 |
The efficacy of 5-fluorouracil bleb needling performed 1 year or more posttrabeculectomy: a retrospective study.
Topics: Aged; Aged, 80 and over; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Imm | 2009 |
Recurrence of treated ciliary body melanoma following trabeculectomy.
Topics: Aged; Brachytherapy; Ciliary Body; Combined Modality Therapy; Conjunctival Neoplasms; Eye Enucleatio | 2009 |
Ophthalmic drug-loaded N,O-carboxymethyl chitosan hydrogels: synthesis, in vitro and in vivo evaluation.
Topics: Administration, Topical; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevaciz | 2010 |
Antimetabolite application technique in trabeculectomy surgery.
Topics: Antimetabolites; Drug Delivery Systems; Fibrosis; Fluorouracil; Glaucoma; Humans; Intraoperative Car | 2011 |
Bleb needling with subconjunctival injection of sodium hyaluronate 1.4%: 1-year outcomes.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Conjunctiva; Drug Therapy, Combination; Female; F | 2011 |
Snailtrack corneal changes following subconjunctival injection of 5-fluorouracil.
Topics: Antimetabolites; Conjunctiva; Corneal Diseases; Endothelium, Corneal; Fluorouracil; Glaucoma; Humans | 2012 |
Avastin in glaucoma surgery...
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antimetabolites; Bevacizumab; Female; Fl | 2012 |
Enhanced trabeculectomy in a UK district general hospital setting: is selective use of 5-fluorouracil all that is required?
Topics: Aged; Aged, 80 and over; Antimetabolites; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Hospita | 2013 |
Trabeculectomy with antiproliferative agents in uveitic glaucoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antineopla | 2002 |
Long-term follow-up of initially successful trabeculectomy with 5-fluorouracil injections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Child; Child, Preschool; Conjunctiva; F | 2002 |
[Interferon-alpha 2b inhibits proliferation of human tenon capsule fibroblasts].
Topics: Antimetabolites; Cell Division; Cells, Cultured; Conjunctiva; Fibroblasts; Filtering Surgery; Fluoro | 1998 |
The role of needle revision and 5-fluorouracil application over the filtration site in the management of bleb failure after trabeculectomy: a prospective study.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorou | 2003 |
Postoperative 5-fluorouracil versus intraoperative mitomycin C in high-risk glaucoma filtering surgery: extended follow up.
Topics: Adult; Aged; Female; Filtering Surgery; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Intrao | 2003 |
Intraoperative 5-fluorouracil application during primary trabeculectomy in Nigeria: a comparative study.
Topics: Aged; Antimetabolites; Developing Countries; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Huma | 2003 |
Late bleb needling.
Topics: Aged; Drainage; Female; Fluorouracil; Glaucoma; Humans; Immunosuppressive Agents; Male; Reoperation; | 2003 |
Needling revision of failed filtering blebs after trabeculectomy: a retrospective study.
Topics: Adult; Aged; Aged, 80 and over; Child, Preschool; Conjunctiva; Female; Fluorouracil; Follow-Up Studi | 2003 |
Intensified postoperative care versus conventional follow-up: a retrospective long-term analysis of 177 trabeculectomies.
Topics: Aged; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle | 2004 |
The case against glaucoma drainage implant surgery in patients with a poor prognosis for standard filtering procedure.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Fibrosis; Fluorouracil; Glaucoma; Glau | 2004 |
Trabeculectomy outcomes in a Malaysian general hospital.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Chemotherapy, Adjuvant; Combined Modality Therapy; | 2003 |
Trabeculectomy and antimetabolites.
Topics: Antimetabolites; Cicatrix; Clinical Competence; Fluorouracil; Glaucoma; Humans; Mitomycin; Trabecule | 2004 |
National survey of antimetabolite use in glaucoma surgery in the United Kingdom.
Topics: Antimetabolites; Fluorouracil; Glaucoma; Health Care Surveys; Humans; Intraoperative Care; Mitomycin | 2004 |
Needle revision of failed filtering blebs using 5-Fluorouracil and a combined ab-externo and ab-interno approach.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Conjunctiva; Fe | 2005 |
Augmented trabeculectomy in paediatric glaucoma.
Topics: Antimetabolites; Child; Child, Preschool; Combined Modality Therapy; Female; Fluorouracil; Glaucoma; | 2005 |
Histopathologic features of conjunctival filtering blebs.
Topics: Cell Count; Conjunctiva; Epithelial Cells; Fibrosis; Fluorouracil; Glaucoma; Goblet Cells; Humans; M | 2005 |
2002 survey of the American Glaucoma Society: practice preferences for glaucoma surgery and antifibrotic use.
Topics: Antineoplastic Agents; Drug Utilization; Fibrosis; Filtering Surgery; Fluorouracil; Glaucoma; Glauco | 2005 |
[The long-term effect of phacoemulsification combined with trabeculectomy and intraoperative 5-fluorouracil in glaucoma patients].
Topics: Adult; Aged; Aged, 80 and over; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; | 2005 |
Ahmed valve drainage implant surgery in the management of paediatric aphakic glaucoma.
Topics: Adolescent; Antihypertensive Agents; Aphakia, Postcataract; Child; Child, Preschool; Female; Fluorou | 2005 |
Short term experience with "modern" trabeculectomy augmented with intraoperative antimetabolites.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Fluorouracil; Follow-Up Studies; Glauco | 2005 |
[Subconjuctival application of 5-fluorouracil (5-FU) following surgical treatment of glaucoma with deep sclerectomy--indications, complications and initial evaluation of effectiveness].
Topics: Aged; Aged, 80 and over; Antimetabolites; Chemotherapy, Adjuvant; Female; Fluorouracil; Glaucoma; Hu | 2005 |
Audit of trabeculectomy at a tertiary referral hospital in East Africa.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Antimetabolites; Female; Fluorouracil; Glau | 2005 |
Is intraocular pressure in the early postoperative period predictive of antimetabolite-augmented filtration surgery success?
Topics: Aged; Antimetabolites; Combined Modality Therapy; Female; Fluorouracil; Glaucoma; Humans; Intraocula | 2005 |
[Visual acuty after trabeculectomy].
Topics: Antimetabolites; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Tr | 2005 |
Comparison of two clinical Bleb grading systems.
Topics: Blister; Diagnostic Techniques, Ophthalmological; Fluorouracil; Glaucoma; Humans; Mitomycin; Prospec | 2006 |
[Clinical observation of needle revision and 5-fluorouracil subconjunctival injection on the dysfunctional filtering blebs].
Topics: Adult; Aged; Combined Modality Therapy; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Glauco | 2005 |
Mitomycin C augmented glaucoma surgery: evolution of filtering bleb avascularity, transconjunctival oozing, and leaks.
Topics: Aged; Blister; Conjunctiva; Conjunctival Diseases; Female; Fluorouracil; Glaucoma; Humans; Intraocul | 2006 |
Review of consecutive phacotrabeculectomies supplemented with early needle revision and antimetabolites.
Topics: Aged; Aged, 80 and over; Antimetabolites; Cataract; Female; Fluorouracil; Glaucoma; Humans; Intraocu | 2006 |
[Needle revision of late failing filtering blebs after glaucoma surgery].
Topics: Aged; Aged, 80 and over; Female; Filtering Surgery; Fluorouracil; Glaucoma; Humans; Immunosuppressiv | 2006 |
Dose, timing and frequency of subconjunctival 5-fluorouracil injections after glaucoma filtering surgery.
Topics: Adult; Aged; Aged, 80 and over; Conjunctiva; Female; Fluorouracil; Glaucoma; Humans; Immunosuppressi | 2007 |
Immediate postoperative intraocular pressure measurements after trabeculectomy with releasable sutures.
Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; False Negative Reactions; Female; Fluorou | 2006 |
Intraocular pressure outcome in primary 5FU phacotrabeculectomies compared with 5FU trabeculectomies.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cataract; Combined Modality Therapy | 2006 |
[Mitomycin C versus 5-FU in failing blebs needling].
Topics: Filtering Surgery; Fluorouracil; Glaucoma; Humans; Mitomycin; Punctures; Treatment Failure | 2006 |
Phacotrabeculectomy study.
Topics: Alkylating Agents; Antihypertensive Agents; Cataract; Fluorouracil; Glaucoma; Humans; Intraocular Pr | 2007 |
[Late needling with 5-fluorouracil when scarring of filtering bleb seems imminent].
Topics: Blister; Cicatrix; Cicatrix, Hypertrophic; Drug Administration Schedule; Filtering Surgery; Fluorour | 2007 |
[Comparison of the suppressing capecitabine and 5-fluorouracil effects on the pronounce of inflammatory cells score in the induction of episcleral fibrosis after trabeculectomy].
Topics: Animals; Capecitabine; Deoxycytidine; Fibrosis; Fluorouracil; Glaucoma; Inflammation; Rabbits; Scler | 2007 |
Post-operative complication of trabeculectomy in Ibadan, Nigeria: outcome of 1-year follow-up.
Topics: Adult; Aged; Anterior Chamber; Antimetabolites; Blister; Epidemiologic Methods; Female; Fluorouracil | 2009 |
Needling revision of trabeculectomies bleb morphology and long-term survival.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Conjunctiva; Female; Fluorouracil; Glaucoma; Humans | 2008 |
[Drug-induced eye lesions in the aged].
Topics: Aged; Antipsychotic Agents; Aspirin; Cataract; Conjunctival Diseases; Corneal Diseases; Eye Diseases | 1983 |
5-fluorouracil and glaucoma filtering surgery. II. A pilot study.
Topics: Adolescent; Adult; Aged; Cataract Extraction; Child; Cicatrix; Combined Modality Therapy; Dose-Respo | 1984 |
5-fluorouracil and glaucoma filtering surgery: I. An animal model.
Topics: Animals; Aotus trivirgatus; Cicatrix; Combined Modality Therapy; Fibroblasts; Fluorouracil; Glaucoma | 1984 |
Effect of mitomycin C and fluorouracil-supplemented trabeculectomies on the anterior segment.
Topics: Aged; Anterior Eye Segment; Cataract; Cell Count; Chemotherapy, Adjuvant; Female; Fluorouracil; Glau | 1995 |
Removable sutures in glaucoma surgery.
Topics: Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Mitomycin; Suture Techniques; Time Factors; Tr | 1994 |
One-year follow-up results of combined mitomycin C trabeculectomy and extracapsular cataract extraction.
Topics: Adult; Aged; Astigmatism; Cataract; Cataract Extraction; Female; Fluorouracil; Follow-Up Studies; Gl | 1995 |
Depot drug delivery system for 5-fluorouracil after filtration surgery in the rabbit.
Topics: Animals; Biocompatible Materials; Biodegradation, Environmental; Conjunctiva; Drug Delivery Systems; | 1994 |
Incidence of complications following 5-fluorouracil with trabeculectomies.
Topics: Combined Modality Therapy; Corneal Diseases; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Inci | 1993 |
Histopathologic effects of mitomycin C after trabeculectomy in human glaucomatous eyes with persistent hypotony.
Topics: Adult; Aged; Ciliary Body; Combined Modality Therapy; Conjunctiva; Female; Fluorouracil; Glaucoma; H | 1994 |
Single intraoperative applications of 5-fluorouracil during filtration surgery: early results.
Topics: Adolescent; Adult; Aged; Child, Preschool; Female; Filtration; Fluorouracil; Glaucoma; Humans; Intra | 1994 |
[5-fluorouracil injection treatment after fistulating glaucoma operations].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Combined Modality Therapy; Female; Fluorouracil; | 1993 |
[5-fluorouracil in goniotrepanation with poor prognosis. Results of 1-year follow-up].
Topics: Adult; Aged; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; I | 1993 |
Intra-operative use of 5-fluorouracil in glaucoma filtering surgery.
Topics: Adult; Aged; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Infant; I | 1993 |
5-Fluorouracil vs single-plate molteno implantation.
Topics: Combined Modality Therapy; Fluorouracil; Glaucoma; Humans; Prostheses and Implants; Trabeculectomy | 1994 |
[The effect of antimetabolites on healing in anti-glaucoma surgery].
Topics: Fluorouracil; Glaucoma; Humans; Postoperative Care | 1993 |
Dangers of direct injection of antimetabolites into filtration blebs.
Topics: Antimetabolites; Contraindications; Fluorouracil; Glaucoma; Humans; Injections | 1993 |
Intraoperative 5-fluorouracil for filtration surgery in the rabbit.
Topics: Animals; Conjunctiva; Double-Blind Method; Fluorouracil; Glaucoma; Injections; Intraocular Pressure; | 1993 |
Trabeculectomy with 5-fluorouracil vs single-plate Molteno implantation.
Topics: Adult; Aged; Combined Modality Therapy; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure | 1993 |
5-FU-supplemented phacoemulsification, posterior chamber intraocular lens implantation, and trabeculectomy.
Topics: Aged; Cataract Extraction; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; | 1993 |
The role of 5-fluorouracil in complicated glaucomas.
Topics: Adult; Aphakia; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Glaucoma, Neovascular; Humans; In | 1993 |
Filtering surgery with 5-fluorouracil subsequent to Molteno implant.
Topics: Adolescent; Adult; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Injections; Intraocula | 1993 |
The use of 5-fluorouracil in glaucoma filtration surgery.
Topics: Aged; Aged, 80 and over; Female; Fibroblasts; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Inj | 1993 |
Holmium laser sclerectomy. Success and complications.
Topics: Aged; Choroid Hemorrhage; Chronic Disease; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intrao | 1993 |
Sturge-Weber syndrome: management of glaucoma with combined trabeculotomy-trabeculectomy.
Topics: Child; Child, Preschool; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Infant; Infant, | 1993 |
Trabeculectomy with 5-fluorouracil in complicated glaucoma.
Topics: Adolescent; Adult; Aged; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Glaucom | 1993 |
[The anti-cicatrization effect of low dosage 5-Fu after trabeculectomy in late glaucoma].
Topics: Adolescent; Adult; Aged; Child; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Male; Mid | 1993 |
Prolonged localized tissue effects from 5-minute exposures to fluorouracil and mitomycin C.
Topics: Animals; Biopsy; Conjunctiva; Disease Models, Animal; Drug Evaluation, Preclinical; Fibroblasts; Flu | 1993 |
Additional failures after filtering with 5-FU.
Topics: Endophthalmitis; Fluorouracil; Glaucoma; Humans; Treatment Failure | 1993 |
[Assessment of anti-proliferative and anti-inflammatory drugs for treatment of ocular fibroblast proliferation using dynamic microscope image processing scanner].
Topics: 3T3 Cells; Animals; Cell Division; Cell Movement; Colchicine; Fluorouracil; Glaucoma; Image Processi | 1993 |
Anterior chamber reaction after mitomycin and 5-fluorouracil trabeculectomy: a comparative study.
Topics: Anterior Chamber; Aqueous Humor; Biological Transport, Active; Blood; Chemotherapy, Adjuvant; Eye Pr | 1993 |
Subconjunctival THC:YAG ("holmium") laser thermal sclerostomy ab externo. A one-year report.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Cohort Studies; Conjunctiva; Female; Fluorouracil | 1993 |
Effects of intraoperative 5-fluorouracil or mitomycin C on glaucoma filtration surgery in the rabbit.
Topics: Animals; Double-Blind Method; Drug Evaluation, Preclinical; Fluorouracil; Glaucoma; Intraocular Pres | 1993 |
Late complications after glaucoma filtering surgery with adjunctive 5-fluorouracil.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Child; Child, Preschool; Eye Dis | 1993 |
Hypotonous maculopathy after trabeculectomy with subconjunctival 5-fluorouracil.
Topics: Fluorouracil; Glaucoma; Humans; Macula Lutea; Middle Aged; Ocular Hypotension; Retinal Diseases; Tra | 1993 |
Surgical management of post-traumatic angle recession glaucoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anterior Chamber; Child; Combined Modality Therapy; Drai | 1993 |
Treatment of failing glaucoma filtering cystic blebs with tissue plasminogen activator (tPA).
Topics: Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Drug Therapy, Combination; Female; Filtering Surger | 1995 |
Trabeculectomy at the inferior limbus.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anterior Eye Segment; Chemotherapy, Adjuvant; Child; Chi | 1996 |
Encapsulated filtering blebs.
Topics: Filtering Surgery; Fluorouracil; Glaucoma; Gloves, Surgical; Humans; Incidence; Postoperative Compli | 1996 |
Late visual loss secondary to filtering bleb exuberance.
Topics: Chemotherapy, Adjuvant; Conjunctiva; Fluorouracil; Glaucoma; Humans; Immunosuppressive Agents; Male; | 1996 |
Purity and stability assessment of a semi-solid poly(ortho ester) used in drug delivery systems.
Topics: Argon; Biocompatible Materials; Drug Delivery Systems; Drug Stability; Drug Storage; Fluorouracil; G | 1996 |
5-FU loaded pHEMA drainage implants for glaucoma-filtering surgery: device design and in vitro release kinetics.
Topics: Animals; Biocompatible Materials; Cell Division; Combined Modality Therapy; Dogs; Drug Implants; Equ | 1996 |
[Biodegradable controlled-release 5-FU implant in the surgery for glaucoma. Experimental study].
Topics: Animals; Antimetabolites; Biocompatible Materials; Delayed-Action Preparations; Fluorouracil; Glauco | 1996 |
[Subconjunctival 5-fluorouracil polyphase liposome interference with scar formation in experimental filtration surgery].
Topics: Animals; Cicatrix; Drug Carriers; Female; Filtering Surgery; Fluorouracil; Glaucoma; Liposomes; Male | 1996 |
"Late endophthalmitis"--filtering surgery time bomb?
Topics: Antimetabolites; Aqueous Humor; Bacteria; Chemotherapy, Adjuvant; Endophthalmitis; Eye Infections, B | 1996 |
A novel MMC-loaded pHEMA drainage device for the treatment of glaucoma: in vitro and in vivo studies.
Topics: Administration, Topical; Animals; Antibiotics, Antineoplastic; Conjunctiva; Cornea; Delayed-Action P | 1996 |
In vitro and in vivo evaluation in rabbits of a controlled release 5-fluorouracil subconjunctival implant based on poly(D,L-lactide-co-glycolide).
Topics: Animals; Biocompatible Materials; Conjunctiva; Delayed-Action Preparations; Drug Implants; Fluoroura | 1996 |
Corneal ectasia secondary to excessive ocular massage following trabeculectomy with 5-fluorouracil.
Topics: Adult; Antimetabolites; Corneal Diseases; Dilatation, Pathologic; Fluorouracil; Glaucoma; Humans; Ma | 1996 |
Five-year follow-up of the Fluorouracil Filtering Surgery Study.
Topics: Antimetabolites; Filtering Surgery; Fluorouracil; Follow-Up Studies; Glaucoma; Humans | 1996 |
Low-dose perioperative 5-fluorouracil in trabeculectomy.
Topics: Antimetabolites; Drug Administration Routes; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Huma | 1996 |
Ultrasonographic findings of the optic disc in congenital glaucoma.
Topics: Antimetabolites; Corneal Opacity; Cryotherapy; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Hu | 1996 |
[Antiproliferative therapy with 5-fluorouracil in erbium:YAG laser sclerostomy ab externo].
Topics: Antimetabolites; Cell Division; Cicatrix; Combined Modality Therapy; Female; Fluorouracil; Glaucoma; | 1996 |
Results of intraoperative 5-fluorouracil or lower dose mitomycin-C administration on initial trabeculectomy surgery.
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites; Chemotherapy, Adjuvant | 1997 |
Needling revision of glaucoma drainage device filtering blebs.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Chemotherapy, Adjuvant; Drainage; Female; Fluoroura | 1997 |
Use of antifibrosis agents and glaucoma drainage devices in the American and Japanese Glaucoma Societies.
Topics: Chemotherapy, Adjuvant; Data Collection; Dose-Response Relationship, Drug; Drainage; Fibrosis; Fluor | 1997 |
Late onset of sequential multifocal bleb leaks after glaucoma filtration surgery with 5-fluorouracil and mitomycin C.
Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites; Chemotherapy, Adjuvant; Conjunctiva; Female; Flu | 1997 |
Small incision trabeculectomy avoiding Tenon's capsule. A new procedure for glaucoma surgery.
Topics: Adult; Aged; Aged, 80 and over; Conjunctiva; Connective Tissue; Fluorouracil; Follow-Up Studies; Gla | 1997 |
5-Fluorouracil in primary combined glaucoma surgery.
Topics: Antimetabolites; Cornea; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Lenses, Intraocular; | 1997 |
Temporal corneal phacoemulsification in filtered glaucoma patients.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Cornea; Female; Fluorouracil; Follow-Up Studies; Glau | 1997 |
Long-term results and complications after trabeculectomy with a single per-operative application of 5-fluorouracil.
Topics: Adult; Aged; Antimetabolites; Eye Diseases; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Human | 1997 |
Modification of trabeculectomy with single-dose intraoperative 5-Fluorouracil application.
Topics: Antimetabolites; Chemotherapy, Adjuvant; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; | 1998 |
Late removal of releasable sutures after trabeculectomy or combined trabeculectomy with cataract extraction supplemented with antifibrotics.
Topics: Aged; Cataract Extraction; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pr | 1998 |
Late-onset bleb leaks after glaucoma filtering surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aqueous Humor; Cataract Extraction; Chemotherapy, Adjuva | 1998 |
[A case of Cogan-Reese syndrome (iris nevus syndrome)].
Topics: Adult; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; F | 1997 |
Antimetabolites in glaucoma surgery: our experiences and results.
Topics: Antimetabolites; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Intraopera | 1997 |
[Peroperative administration of 5-fluorouracil during trabeculectomy in complicated glaucoma in children].
Topics: Adolescent; Antimetabolites; Child; Child, Preschool; Female; Fluorouracil; Glaucoma; Humans; Intrao | 1998 |
Management of large, leaking, and inadvertent filtering blebs with the neodymium:YAG laser.
Topics: Aged; Aqueous Humor; Female; Filtering Surgery; Fluorouracil; Glaucoma; Humans; Intraocular Pressure | 1998 |
Needling revision of glaucoma drainage device filtering blebs.
Topics: Chemotherapy, Adjuvant; Drainage; Filtering Surgery; Fluorouracil; Glaucoma; Humans; Intraocular Pre | 1998 |
Trabeculectomy with intraoperative 5-fluorouracil.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Fluorouracil; Glaucoma; Humans; Int | 1998 |
Trabeculectomy survival with and without intra-operative 5-fluorouracil application in an Asian population.
Topics: Administration, Topical; Antimetabolites; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; | 1998 |
Occlusive ligature and standardized fenestration of a Baerveldt tube with and without antimetabolites for early postoperative intraocular pressure control.
Topics: Aged; Antimetabolites; Aqueous Humor; Female; Fluorouracil; Glaucoma; Glaucoma Drainage Implants; Hu | 1998 |
Comparison of phacotrabeculectomy with 5-fluorouracil, mitomycin-C, and without antifibrotic agents.
Topics: Aged; Cataract; Chemotherapy, Adjuvant; Fibrosis; Fluorouracil; Glaucoma; Humans; Intraocular Pressu | 1999 |
[Use of "low dose" 5-fluorouracil during trabeculectomy].
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Female; Fluorouracil; Follow-Up Studies; Glaucoma; | 1999 |
[The inhibitory effect of tissue plasminogen activator combined with 5-fluorouracil polyphase liposome on the scar formation in experimental filtration surgery].
Topics: Animals; Cicatrix; Drug Carriers; Drug Synergism; Drug Therapy, Combination; Female; Fibrosis; Fluor | 1997 |
Late-onset, bleb-associated endophthalmitis following glaucoma filtering surgery with or without antifibrotic agents.
Topics: Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Endophthalmitis; Female; Filtration; Fluoro | 1999 |
Collagen type I and III synthesis by Tenon's capsule fibroblasts in culture: individual patient characteristics and response to mitomycin C, 5-fluorouracil, and ascorbic acid.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Ascorbic Acid; Cells, Cultured; Child; | 1999 |
Long-term follow-up of trabeculectomy with intraoperative 5-fluorouracil for uveitis-related glaucoma.
Topics: Adolescent; Adult; Aged; Antimetabolites; Child; Female; Fluorouracil; Follow-Up Studies; Glaucoma; | 2000 |
After-cataract and secondary glaucoma in the aphakic infant rabbit.
Topics: Animals; Animals, Newborn; Anterior Chamber; Aphakia, Postcataract; Cataract; Fluorouracil; Glaucoma | 2000 |
Risk factors for development of post-trabeculectomy endophthalmitis.
Topics: Aged; Antimetabolites; Case-Control Studies; Diabetes Complications; Endophthalmitis; Female; Fluoro | 2000 |
Outcomes of combined cataract extraction, lens implantation, and trabeculectomy surgeries.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Cataract; Cataract Extraction; Female; | 2000 |
Success criteria and success rates in trabeculectomy with and without intraoperative antimetabolites using intensified postoperative care (IPC).
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Female; Fluorouracil; Glaucoma; Humans; Intraocular | 2000 |
[Use of 5-fluorouracil in trabeculectomy].
Topics: Adult; Aged; Aged, 80 and over; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Male; | 2000 |
Should antiproliferatives be used in filtering surgery of normal tension glaucoma?
Topics: Antineoplastic Agents; Filtering Surgery; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Mito | 2001 |
Long-term surgical outcomes of patients with glaucoma secondary to the iridocorneal endothelial syndrome.
Topics: Adult; Antihypertensive Agents; Corneal Diseases; Endothelium, Corneal; Fluorouracil; Follow-Up Stud | 2001 |
Slow release of the antimetabolite 5-fluorouracil (5-FU) from modified Baerveldt glaucoma drains to prolong drain function.
Topics: Animals; Antimetabolites; Biocompatible Materials; Collagen; Delayed-Action Preparations; Drug Impla | 2001 |
Glaucoma surgery treatment patterns of ASCRS members--2000 survey.
Topics: Cross-Sectional Studies; Filtering Surgery; Fluorouracil; Glaucoma; Health Surveys; Humans; Middle A | 2001 |
The efficacy and safety of intraoperative and/or postoperative 5-fluorouracil in trabeculectomy and phacotrabeculectomy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Cataract; Female; Fluorouracil; Glaucom | 2001 |
Risk factors for failure of 5-fluorouracil needling revision for failed conjunctival filtration blebs.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cataract Extraction; Conjunctiva; Female; | 2001 |
[Influence on tear film of postoperative 5-fluourouracil and intraoperative mitomycin C in glaucoma filtration surgery].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Conjunctiva; Dry Eye Synd | 2001 |
Predictors for success of needle revision of failing filtration blebs.
Topics: Aged; Antimetabolites; Conjunctiva; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Ma | 2002 |
Needling revision with subconjunctival 5-fluorouracil in failing filtering blebs.
Topics: Adult; Aged; Antimetabolites; Female; Fluorouracil; Glaucoma; Humans; Male; Middle Aged; Needles; Po | 2002 |
[Antimetabolites in glaucoma surgery--long-term results].
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Fluorouracil; Glaucoma; Humans; Intraocular Pressur | 2002 |
Complications of 5-fluorouracil after trabeculectomy.
Topics: Adult; Fluorouracil; Glaucoma; Humans; Postoperative Care; Trabeculectomy | 1992 |
Antimetabolites in the surgical treatment of glaucomas.
Topics: Animals; Aotidae; Cell Division; Fibroblasts; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; | 1992 |
Glaucoma filtering surgery with postoperative 5-fluorouracil in patients with intraocular inflammatory disease.
Topics: Adolescent; Adult; Aged; Cataract Extraction; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; | 1992 |
Hypotonous maculopathy after trabeculectomy with subconjunctival 5-fluorouracil.
Topics: Adult; Aged; Aged, 80 and over; Female; Fluorescein Angiography; Fluorouracil; Fundus Oculi; Glaucom | 1992 |
Toxic effects of 5-fluorouracil on fibroblasts following trabeculectomy.
Topics: Adult; Cicatrix; Conjunctival Diseases; Fibroblasts; Fluorouracil; Glaucoma; Humans; Inclusion Bodie | 1992 |
[Use of 5-fluorouracil in complicated cases of glaucoma--personal experience].
Topics: Adolescent; Adult; Aged; Female; Fluorouracil; Glaucoma; Humans; Injections; Male; Middle Aged; Trab | 1992 |
Intraoperative and post operative treatment with 5-fluorouracil and mitomycin-c: long term effects in vivo on subconjunctival and scleral fibroblasts.
Topics: Animals; Cell Division; Cells, Cultured; Conjunctiva; Fibroblasts; Fluorouracil; Glaucoma; Injection | 1992 |
Intraoperative application of 5-fluorouracil during trabeculectomy.
Topics: Adult; Aged; Aged, 80 and over; Cicatrix; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; | 1992 |
Who should receive antimetabolites after filtering surgery?
Topics: Antimetabolites; Fluorouracil; Glaucoma; Humans; Mitomycin; Postoperative Care | 1992 |
Combined cataract extraction and filtering surgery.
Topics: Cataract Extraction; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Lenses, In | 1992 |
Phacoemulsification, foldable IOL, Holmium laser sclerostomy, and 5-FU.
Topics: Cataract Extraction; Fluorouracil; Glaucoma; Humans; Injections; Laser Therapy; Lenses, Intraocular; | 1992 |
Subconjunctival injection of 5-fluorouracil following trabeculectomy for congenital and infantile glaucoma.
Topics: Child; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Injections; Intraocul | 1992 |
Molteno implants.
Topics: Cysts; Eye Diseases; Fluorouracil; Glaucoma; Humans; Injections; Postoperative Complications; Prosth | 1992 |
Design and results of trabeculectomy operation for use with 5-fluorouracil.
Topics: Adult; Aged; Aged, 80 and over; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Male; | 1992 |
Inhibition of human subconjunctival fibroblast proliferation by immunotoxin.
Topics: Antibodies, Monoclonal; Cell Count; Cell Division; Cell Survival; Cells, Cultured; Conjunctiva; Fibr | 1992 |
In vitro release of hydrophobic drugs from polyanhydride disks.
Topics: Alkaloids; Cell Division; Cells, Cultured; Decanoic Acids; Delayed-Action Preparations; Dicarboxylic | 1991 |
Indications for postoperative fluorouracil therapy.
Topics: Aqueous Humor; Drainage; Fibroblasts; Fluorouracil; Glaucoma; Humans; Postoperative Care; Prostheses | 1992 |
5-FU trabeculectomy.
Topics: Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Trabeculectomy | 1992 |
Regulating the dose of 5-fluorouracil to prevent filtering bleb scarring.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anterior Chamber; Child; Cicatrix; Conjunctiva; Dosage F | 1991 |
Effect of gamma-interferon on fibroblast proliferation and collagen synthesis after glaucoma filtering surgery in white rabbits.
Topics: Animals; Anterior Chamber; Cell Division; Collagen; Fibroblasts; Fluorouracil; Glaucoma; Interferon- | 1991 |
[5-Fu as remedy for unsuccessful glaucoma filtration surgery].
Topics: Adolescent; Adult; Child; Female; Fluorouracil; Glaucoma; Humans; Injections; Intraocular Pressure; | 1991 |
Glaucoma filtration surgery: new horizontal mattress closure of conjunctival incision.
Topics: Cataract Extraction; Conjunctiva; Fluorouracil; Glaucoma; Humans; Surgical Wound Dehiscence; Suture | 1991 |
Initial 5-fluorouracil trabeculectomy in uncomplicated glaucoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Evaluation Studies as Topic; Female; Fluorouracil; Follo | 1991 |
Late bleb-related endophthalmitis after trabeculectomy with adjunctive 5-fluorouracil.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Child; Child, Preschool; Endophth | 1991 |
Subconjunctival THC:YAG laser thermal sclerostomy.
Topics: Adult; Aged; Aged, 80 and over; Child; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Glaucom | 1991 |
5-fluorouracil and beyond.
Topics: Child; Cicatrix; Fluorouracil; Glaucoma; Humans; Trabeculectomy | 1991 |
5-Fluorouracil and filtering surgery.
Topics: Fluorouracil; Glaucoma; Humans; Prognosis; Trabeculectomy; Wound Healing | 1991 |
Remission of anterior uveitis by subconjunctival fluorouracil.
Topics: Aged; Conjunctiva; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Middle A | 1991 |
5-Fluorouracil after trabeculectomy and the iridocorneal endothelial syndrome.
Topics: Adult; Cataract Extraction; Conjunctiva; Corneal Diseases; Endothelium, Corneal; Fluorouracil; Follo | 1991 |
Corneal penetration of 5-fluorouracil and its improvement by prodrug derivatization in the albino rabbit: implication in glaucoma filtration surgery.
Topics: Animals; Atenolol; Cornea; Female; Fluorouracil; Glaucoma; Histological Techniques; Hydrolysis; Osmo | 1991 |
Subconjunctival 5-fluorouracil and herpes simplex keratitis.
Topics: Eye Diseases; Fluorouracil; Glaucoma; Humans; Keratitis, Dendritic; Male; Middle Aged; Postoperative | 1991 |
Restoring the function of the failed bleb.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drainage; Female; Fluorouracil; Glaucoma; Humans; | 1991 |
Filtering surgery with 5-fluorouracil: a second course.
Topics: Adult; Aged; Combined Modality Therapy; Conjunctiva; Female; Fluorouracil; Glaucoma; Humans; Injecti | 1990 |
Using fluorouracil in surgical therapy for glaucoma.
Topics: Combined Modality Therapy; Drainage; Fluorouracil; Glaucoma; Humans; Postoperative Care | 1990 |
Primate trabeculectomies with 5-fluorouracil collagen implants.
Topics: Animals; Collagen; Drug Implants; Fluorouracil; Glaucoma; Macaca; Trabeculectomy | 1990 |
Glaucoma secondary to epithelial downgrowth and 5-fluorouracil.
Topics: Anterior Chamber; Cataract Extraction; Cell Division; Corneal Diseases; Epithelium; Eye Enucleation; | 1990 |
[Prevention of scarring of filtering bleb by 5-fluorouracil].
Topics: Conjunctiva; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Injections; Postoperative Care; Trab | 1990 |
Trabeculectomy with 5-fluorouracil for adult inflammatory glaucoma.
Topics: Adult; Aged; Female; Fluorometholone; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Inflammatio | 1990 |
Fluorouracil filtering surgery study one-year follow-up.
Topics: Cataract Extraction; Combined Modality Therapy; Fluorouracil; Glaucoma; Humans; Trabeculectomy | 1990 |
Needle revision with and without 5-fluorouracil for the treatment of failed filtering blebs.
Topics: Adult; Aged; Aged, 80 and over; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Male; Mid | 1990 |
5-Fluorouracil and glaucoma filtering surgery. III. Intermediate follow-up of a pilot study.
Topics: Aphakia; Conjunctiva; Eye; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Injections; Neovascula | 1986 |
Delivery of antifibroblast agents as adjuncts to filtration surgery--Part II: Delivery of 5-fluorouracil and bleomycin in a collagen implant: pilot study in the rabbit.
Topics: Animals; Bleomycin; Cell Division; Collagen; Drug Implants; Eye; Female; Fibroblasts; Fluorouracil; | 1986 |
Adjusting the dose of 5-fluorouracil after filtration surgery to minimize side effects.
Topics: Adult; Aged; Female; Fluorouracil; Glaucoma; Humans; Inflammation; Intraocular Pressure; Iris; Male; | 1987 |
[Treatment of neovascular glaucoma by seton and 5-FU].
Topics: Combined Modality Therapy; Diabetes Complications; Fluorouracil; Glaucoma; Humans; Male; Methods; Mi | 1987 |
[Complications of antiglaucoma surgery associated with 5FU. Apropos of a case].
Topics: Adult; Choroid Diseases; Female; Fluorouracil; Glaucoma; Humans; Ocular Motility Disorders; Reoperat | 1989 |
Low-dose 5-fluorouracil and glaucoma filtration surgery.
Topics: Adolescent; Adult; Aged; Child; Cornea; Epithelial Cells; Fluorouracil; Follow-Up Studies; Glaucoma; | 1989 |
External limbal sclerostomy with contact Nd:YAG laser versus surgical knife.
Topics: Animals; Anterior Chamber; Cell Division; Conjunctiva; Fluorouracil; Glaucoma; Intraocular Pressure; | 1989 |
Polyvinyl alcohol membrane permeability characteristics of 5-fluorouracil.
Topics: Delayed-Action Preparations; Diffusion; Fluorouracil; Glaucoma; Humans; Membranes, Artificial; Perme | 1988 |
A randomized study of 5-fluorouracil and filtration surgery.
Topics: Fluorouracil; Glaucoma; Humans; Random Allocation | 1988 |
Glaucoma filtration surgery in rabbits using bioerodible polymers and 5-fluorouracil.
Topics: Animals; Biodegradation, Environmental; Double-Blind Method; Drug Implants; Fluorouracil; Glaucoma; | 1987 |
[Use of 5-fluorouracil in the surgery of glaucoma].
Topics: Conjunctiva; Female; Fibrosis; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressu | 1987 |
Complications of subconjunctival 5-fluorouracil following glaucoma filtering surgery.
Topics: Aged; Aged, 80 and over; Conjunctiva; Conjunctival Diseases; Corneal Diseases; Fluorouracil; Glaucom | 1987 |
5-Fluorouracil for trabeculectomy in glaucoma.
Topics: Cicatrix; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Pos | 1987 |
Glaucoma filtering surgery with 5-fluorouracil.
Topics: Actuarial Analysis; Conjunctiva; Fluorouracil; Glaucoma; Humans; Injections; Pilot Projects; Postope | 1987 |
Vital importance of clinical trials.
Topics: Clinical Trials as Topic; Fluorouracil; Glaucoma; Humans | 1986 |
Serious corneal complications of glaucoma filtering surgery with postoperative 5-fluorouracil.
Topics: Aged; Corneal Diseases; Corneal Ulcer; Female; Fluorouracil; Glaucoma; Humans; Male; Middle Aged; Po | 1987 |
Topical fluorouracil. II. Postoperative administration in an animal model of glaucoma filtering surgery.
Topics: Administration, Topical; Animals; Aotus trivirgatus; Electroretinography; Eye; Fluorouracil; Glaucom | 1986 |
[Xeroderma pigmentosum, universal alopecia and associated neuro-ocular symptoms].
Topics: Administration, Topical; Alopecia; Brain Diseases; Fluorouracil; Glaucoma; Humans; Male; Middle Aged | 1973 |