Page last updated: 2024-10-27

fluorouracil and Germinoblastoma

fluorouracil has been researched along with Germinoblastoma in 101 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"The effects of three 1-(halogenalkoxy)alkyl-5-fluorouracil derivatives on cultured mouse lymphoma cells were studied and compared with those of N-methyl-bis-(2-chloroethyl)amine hydrochloride (Lost)."7.68Effects of 1-(halogenalkoxy)alkyl-5-fluorouracil derivatives on cell growth, cell volume and nucleus size of mouse lymphoma cells. ( Jaeger, KH; Reitz, M, 1992)
"Uridine enhances the growth inhibition due to 5-fluorouracil (FUra) in a cultured mouse T-cell lymphoma (S-49)."7.67Enhancement by uridine of the anabolism of 5-fluorouracil in mouse T-lymphoma (S-49) cells. ( Klubes, P; Parker, WB, 1985)
", 45:4249-4256, 1985) that uridine (10 microM) enhanced the cytotoxicity of 5-fluorouracil (FUra) in cultured mouse T-lymphoma (S-49) cells."7.67Dissociation of 5-fluorouracil-induced DNA fragmentation from either its incorporation into DNA or its cytotoxicity in murine T-lymphoma (S-49) cells. ( Kennedy, KA; Klubes, P; Parker, WB, 1987)
"The mouse T-lymphoma (S-49) cell line is useful for individually studying RNA- and DNA-directed effects of 5-fluoropyrimidines."7.66Regulation of RNA- and DNA-directed actions of 5-fluoropyrimidines in mouse T-lymphoma (S-49) cells. ( Day, JL; Mandel, HG; Maybaum, J; Sadee, W; Ullman, B, 1980)
"SUMMARY-A model has been derived for the effect of the chemotherapeutic agents cyclophosphamide (CY), 5-fluorouracil (5-FU), and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) on the survival of mice bearing a transplantable lymphoma."7.64Survival of mice bearing a transplanted syngeneic lymphoma following treatment with cyclophosphamide, 5-fluorouracil, or 1,3-bis(2-chloroethyl)-1-nitrosourea. ( Bruce, WR; Meeker, BE; Valeriote, FA, 1967)
" This report describes a Phase Ib clinical trial investigating PG-11047 in combination with cytotoxic and anti-angiogenic chemotherapeutic agents in patients with advanced refractory metastatic solid tumors or lymphoma."7.01A Phase Ib multicenter, dose-escalation study of the polyamine analogue PG-11047 in combination with gemcitabine, docetaxel, bevacizumab, erlotinib, cisplatin, 5-fluorouracil, or sunitinib in patients with advanced solid tumors or lymphoma. ( Becerra, CHR; Boyd, TE; Casero, RA; Conkling, PR; Fitzgerald, M; Garbo, LE; Jotte, RM; Marton, LJ; Murray Stewart, T; Richards, DA; Smith, DA; Stephenson, JJ; Vogelzang, NJ; Von Hoff, D; Wu, HH, 2021)
"At this juncture in the development of paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ), knowledge about the agent's pharmacologic behavior and clinical antitumor activity in less common neoplasms is being elucidated."4.79Paclitaxel pharmacology and other tumor types. ( Rowinsky, EK, 1997)
" Here, we employed a lymphoma model to characterize tumor-associated circulating neutrophils, including their sensitivity to 5-fluorouracil (5-FU), busulfan (Bu) or treosulfan (Treo)."3.83Suppressive effects of low-dose 5-fluorouracil, busulfan or treosulfan on the expansion of circulatory neutrophils and myeloid derived immunosuppressor cells in tumor-bearing mice. ( Abedi-Valugerdi, M; Hassan, M; Pillai, PR; Sadeghi, B; Wolfsberger, J; Zhao, Y; Zheng, W, 2016)
"We pretreated cell lines derived from human melanomas, adenocarcinomas, and lymphomas with the PPIs omeprazole, esomeprazole, or pantoprazole and tested their response to cytotoxic drugs in cell death assays."3.72Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. ( Arancia, G; Belardelli, F; De Milito, A; Fais, S; Federici, C; Iessi, E; Logozzi, M; Lozupone, F; Luciani, F; Lugini, L; Marra, M; Molinari, A; Montinaro, A; Parmiani, G; Rivoltini, L; Spada, M, 2004)
"A treatment schedule for primary intraocular lymphoma consisting of methotrexate intravitreal injections every 48 to 72 hours provides therapeutic drug concentrations in the vitreous and, in combination with fluorouracil and dexamethasone, appears to be safe in the rabbit eye."3.71Pharmacokinetics and toxicity of intravitreal chemotherapy for primary intraocular lymphoma. ( Chan, CC; Nussenblatt, RB; Reed, GF; Robinson, MR; Sung, C; Tansey, G; Velez, G; Yuan, P, 2001)
"The effects of three 1-(halogenalkoxy)alkyl-5-fluorouracil derivatives on cultured mouse lymphoma cells were studied and compared with those of N-methyl-bis-(2-chloroethyl)amine hydrochloride (Lost)."3.68Effects of 1-(halogenalkoxy)alkyl-5-fluorouracil derivatives on cell growth, cell volume and nucleus size of mouse lymphoma cells. ( Jaeger, KH; Reitz, M, 1992)
"From wild type mouse lymphoma cells, a clone, (FURT-1A), was isolated by virtue of its resistance to 1 microM 5-fluorouracil and 10 microM thymidine."3.67Biochemical phenotype of 5-fluorouracil-resistant murine T-lymphoblasts with genetically altered CTP synthetase activity. ( Aronow, B; Lassetter, J; Ullman, B; Washtien, W; Watts, T, 1984)
"Uridine enhances the growth inhibition due to 5-fluorouracil (FUra) in a cultured mouse T-cell lymphoma (S-49)."3.67Enhancement by uridine of the anabolism of 5-fluorouracil in mouse T-lymphoma (S-49) cells. ( Klubes, P; Parker, WB, 1985)
"From wildtype mouse lymphoma cells, a clone (FURT-1A), was isolated by virtue of its resistance to 1 microM 5-fluorouracil."3.67Mammalian mutants genetically altered in CTP synthetase activity. ( Aronow, B; Ullman, B, 1986)
", 45:4249-4256, 1985) that uridine (10 microM) enhanced the cytotoxicity of 5-fluorouracil (FUra) in cultured mouse T-lymphoma (S-49) cells."3.67Dissociation of 5-fluorouracil-induced DNA fragmentation from either its incorporation into DNA or its cytotoxicity in murine T-lymphoma (S-49) cells. ( Kennedy, KA; Klubes, P; Parker, WB, 1987)
"Seven patients with advanced cutaneous T-cell lymphomas were treated with a combination chemotherapy regimen of vincristine, doxorubicin (Adriamycin), bleomycin, methotrexate, leucovorin factor, 5-FU, and hydrocortisone."3.66Combination chemotherapy for advanced cutaneous T-cell lymphomas. ( Edelson, RL; Lo Gerfo, P; Oster, MW; Raafat, J, 1980)
"The mouse T-lymphoma (S-49) cell line is useful for individually studying RNA- and DNA-directed effects of 5-fluoropyrimidines."3.66Regulation of RNA- and DNA-directed actions of 5-fluoropyrimidines in mouse T-lymphoma (S-49) cells. ( Day, JL; Mandel, HG; Maybaum, J; Sadee, W; Ullman, B, 1980)
"The combined effect of the polysaccharide levan (previously shown to exert a host-dependent as well as direct antitumoural activity) and the cytotoxic agents cyclophosphamide (CY), methotrexate (MTX), vincristine (VINC) and 5-fluoro-uracil (SFU) was studied in Lewis lung carcinoma and AKR lymphoma."3.66Combined effect of levan and cytotoxic agents on the growth of experimental tumours in mice. ( Leibovici, J; Stark, Y; Wolman, M, 1983)
"SUMMARY-A model has been derived for the effect of the chemotherapeutic agents cyclophosphamide (CY), 5-fluorouracil (5-FU), and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) on the survival of mice bearing a transplantable lymphoma."3.64Survival of mice bearing a transplanted syngeneic lymphoma following treatment with cyclophosphamide, 5-fluorouracil, or 1,3-bis(2-chloroethyl)-1-nitrosourea. ( Bruce, WR; Meeker, BE; Valeriote, FA, 1967)
" This report describes a Phase Ib clinical trial investigating PG-11047 in combination with cytotoxic and anti-angiogenic chemotherapeutic agents in patients with advanced refractory metastatic solid tumors or lymphoma."3.01A Phase Ib multicenter, dose-escalation study of the polyamine analogue PG-11047 in combination with gemcitabine, docetaxel, bevacizumab, erlotinib, cisplatin, 5-fluorouracil, or sunitinib in patients with advanced solid tumors or lymphoma. ( Becerra, CHR; Boyd, TE; Casero, RA; Conkling, PR; Fitzgerald, M; Garbo, LE; Jotte, RM; Marton, LJ; Murray Stewart, T; Richards, DA; Smith, DA; Stephenson, JJ; Vogelzang, NJ; Von Hoff, D; Wu, HH, 2021)
" The treatment plan consisted of weekly gemcitabine for three weeks with twice daily dosing of 5-FU and eniluracil for 21 days beginning on day one of gemcitabine."2.70Phase I study of eniluracil, oral 5-fluororacil and gemcitabine in patients with advanced malignancy. ( Alberti, D; Arzoomanian, RZ; Bailey, H; Berlin, JD; Binger, K; Feierabend, C; Marrocha, R; Morgan-Meadows, S; Mulkerin, D; Thomas, JP; Volkman, J; Wilding, G, 2002)
"Vomiting was not consistently related to the excretion of either catecholamine."2.67Delayed chemotherapy-induced nausea is augmented by high levels of endogenous noradrenaline. ( Börjesson, S; Fredrikson, M; Fürst, CJ; Hursti, TJ; Peterson, C; Steineck, G, 1994)
"From 23 patients with advanced non-Hodgkin lymphomas of a high malignancy 11 received a therapy with CVPP scheme; 2 of them came into a complete remission and 3 of them into a partial one."2.65[The so-called partial synchronization in the treatment of malignant lymphomas. A clinical study]. ( Anger, G; Fink, R; Höche, D, 1980)
"Pathological diagnosis was carcinoid, se, ly2, v0, n1."1.56[A Case of Malignant Lymphoma Undergoing HAI Treatment for Multiple Liver Metastases of Carcinoid That Appeared about Nine Years after Resection of Rectal Carcinoid with Liver Metastases]. ( Gofuku, J; Hasuike, Y; Higuchi, I; Ishikawa, A; Miyamoto, M; Mori, Y; Tokunaga, M; Tsuchida, Y; Urano, N, 2020)
"5-fluorouracil (5-FU) has been successfully used to control (or cure) a variety of tumors, but has been only rarely applied to tumors of the lymphoid lineage."1.32Customized mitogen or antibody treatments enhance the sensitivity of lymphoid tumors to 5-fluorouracil in vitro and in vivo. ( D'Costa, S; Hurwitz, JL, 2003)

Research

Studies (101)

TimeframeStudies, this research(%)All Research%
pre-199065 (64.36)18.7374
1990's9 (8.91)18.2507
2000's15 (14.85)29.6817
2010's8 (7.92)24.3611
2020's4 (3.96)2.80

Authors

AuthorsStudies
Vijay Avin, BR1
Thirusangu, P1
Lakshmi Ranganatha, V1
Firdouse, A1
Prabhakar, BT1
Khanum, SA1
Santiago-Vazquez, Y1
Das, S1
Das, U1
Robles-Escajeda, E1
Ortega, NM1
Lema, C1
Varela-Ramírez, A1
Aguilera, RJ1
Balzarini, J1
De Clercq, E1
Dimmock, SG1
Gorecki, DK1
Dimmock, JR1
Pilot, T1
Fratti, A1
Thinselin, C1
Perrichet, A1
Demontoux, L1
Limagne, E1
Derangère, V1
Ilie, A1
Ndiaye, M1
Jacquin, E1
Garrido, C1
Ghiringhelli, F1
Chalmin, F1
Rébé, C1
Hasuike, Y1
Higuchi, I1
Mori, Y1
Ishikawa, A1
Urano, N1
Gofuku, J1
Tsuchida, Y1
Miyamoto, M1
Tokunaga, M1
Murray Stewart, T1
Von Hoff, D1
Fitzgerald, M1
Marton, LJ1
Becerra, CHR1
Boyd, TE1
Conkling, PR1
Garbo, LE1
Jotte, RM1
Richards, DA1
Smith, DA1
Stephenson, JJ1
Vogelzang, NJ1
Wu, HH1
Casero, RA1
Chong, SJF1
Iskandar, K1
Lai, JXH1
Qu, J1
Raman, D1
Valentin, R1
Herbaux, C1
Collins, M1
Low, ICC1
Loh, T1
Davids, M1
Pervaiz, S1
Abedi-Valugerdi, M3
Zheng, W2
Benkessou, F1
Zhao, Y2
Hassan, M3
Shariatpanahi, SP2
Madjidzadeh, K1
Orecchioni, S1
Talarico, G1
Labanca, V1
Calleri, A1
Mancuso, P1
Bertolini, F1
Reneeta, NP1
Thiyonila, B1
Aathmanathan, VS1
Ramya, T1
Chandrasekar, P1
Subramanian, N1
Prajapati, VK1
Krishnan, M1
Smith, SA1
Auseon, AJ1
Wolfsberger, J1
Pillai, PR1
Sadeghi, B1
Bruce, WR4
Valeriote, FA1
Meeker, BE2
Saiko, P2
Ozsvar-Kozma, M1
Graser, G1
Lackner, A1
Grusch, M2
Madlener, S2
Krupitza, G2
Jaeger, W1
Hidvegi, M1
Agarwal, RP1
Fritzer-Szekeres, M2
Szekeres, T2
Waller, EK1
Barlett, N1
Chen, CH1
Mujic, V1
Sussman, H1
Toepker, S1
Grenier, K1
Morgan-Meadows, S1
Thomas, JP1
Mulkerin, D1
Berlin, JD1
Bailey, H1
Binger, K1
Volkman, J1
Alberti, D1
Feierabend, C1
Marrocha, R1
Arzoomanian, RZ1
Wilding, G1
Christina, AJ1
Alwin Jose, M1
Heison Robert, SJ1
Kothai, R1
Chidambaranathan, N1
Muthumani, P1
D'Costa, S1
Hurwitz, JL1
KIDD, JG1
LAMPKIN-HIBBARD, JM1
MUKHERJEE, KL1
HEIDELBERGER, C1
ROOSA, RA1
BRADLEY, TR1
LAW, LW1
HERZENBERG, LA1
MACLEOD, RM1
KING, CE1
HOLLANDER, VP1
KASBEKAR, DK1
GREENBERG, DM1
BOOTH, BA1
SARTORELLI, AC1
FALKSON, G1
SNYMAN, HJ1
KARNOFSKY, DA1
MYHRE, K1
FJAERLI, J1
ROCHLIN, DB1
SMART, CR1
SILVA, A1
BAKER, RR1
GAERTNER, RA1
Dummer, R1
Beyeler, M1
Morcinek, J1
Burg, G1
Oelmann, E1
Haghgu, S1
Kulimova, E1
Mesters, RM1
Kienast, J1
Herbst, H1
Schmitmann, C1
Kolkmeyer, A1
Serve, H1
Berdel, WE1
Luciani, F1
Spada, M1
De Milito, A1
Molinari, A1
Rivoltini, L1
Montinaro, A1
Marra, M1
Lugini, L1
Logozzi, M1
Lozupone, F1
Federici, C1
Iessi, E1
Parmiani, G1
Arancia, G1
Belardelli, F1
Fais, S1
Bauer, W1
Horvath, Z1
Hoechtl, T1
Illmer, C1
Mader, RM1
Schott, H1
Correale, P1
Del Vecchio, MT1
Di Genova, G1
Savellini, GG1
La Placa, M1
Terrosi, C1
Vestri, M1
Urso, R1
Lemonnier, F1
Aquino, A1
Bonmassar, E2
Giorgi, G1
Francini, G1
Cusi, MG1
Jones, B1
Dale, RG1
Gaya, AM1
Li, ML2
Li, CG2
Shu, XH2
Li, MX1
Jia, YJ1
Qin, ZH2
Liu, YJ1
Michael, N1
Madoc-Jones, H1
Takeuchi, S1
Akahoshi, Y1
Kasai, C1
Nishimoto, Y1
Höche, D1
Fink, R1
Anger, G1
Raafat, J1
Oster, MW1
Lo Gerfo, P1
Edelson, RL1
Namba, M1
Miyoshi, T1
Kanamori, T1
Nobuhara, M1
Kimoto, T1
Ogawa, S1
Matsumoto, K1
Tabuchi, K1
Furuta, T1
Fujiwara, T1
Nakasone, S1
Ohnishi, R1
Moriya, Y1
Nishimoto, A1
Doi, A1
Asari, S1
Kasajima, T1
Yamakawa, M1
Maeda, K1
Matsuda, M1
Dobashi, M1
Imai, Y1
Maybaum, J2
Ullman, B4
Mandel, HG1
Day, JL2
Sadee, W3
Aronow, B2
Watts, T1
Lassetter, J1
Washtien, W1
Bedikian, AY1
Chen, TT1
Khankhanian, N1
Heilbrun, LK1
McBride, CM1
McMurtrey, MJ1
Bodey, GP1
Leibovici, J1
Stark, Y1
Wolman, M1
Cohen, MB1
Cassone, A2
Bistoni, F2
Cenci, E2
Pesce, CD1
Tissi, L2
Marconi, P2
Oda, Y1
Mori, K1
Tsuda, E1
Tokuriki, Y1
Tsuda, T1
Jurga, L1
Mrinák, J1
Ponist, J1
Sefara, P1
Berc, A1
Delfina Pesce, C1
Boccanera, M1
Kanzawa, F1
Hoshi, A1
Kuretani, K1
Woodcock, TM1
Martin, DS1
Damin, LA1
Kemeny, NE1
Young, CW1
Fredrikson, M1
Hursti, TJ1
Steineck, G1
Fürst, CJ1
Börjesson, S1
Peterson, C1
Kelliher, MA1
Weckstein, DJ1
Knott, AG1
Wortis, HH1
Rosenberg, N1
Rowinsky, EK1
Yeh, KH1
Yeh, SH1
Chang, YS1
Cheng, AL1
Kawamura, K1
Tasaki, K1
Hamada, H1
Takenaga, K1
Sakiyama, S1
Tagawa, M1
Velez, G1
Yuan, P1
Sung, C1
Tansey, G1
Reed, GF1
Chan, CC1
Nussenblatt, RB1
Robinson, MR1
Levinson, BB1
Martin, DW1
Kopper, L1
Jeney, A1
Lapis, K2
Török, M1
Testorelli, C1
Franco, P1
Goldin, A2
Cudkowicz, G1
Guglielmi, C2
Amadori, S2
Martelli, M1
Papa, G2
Mandelli, F2
Saito, T1
Otaka, T1
Sato, H1
Reitz, M1
Jaeger, KH1
Shinomiya, N1
Katsura, Y1
Tsugita, M1
Noritake, M1
Tsuru, S1
Inedjian, JM1
Thomassin, JM1
Danoy, MC1
Sermet, M1
Geunoun, A1
Parker, WB2
Klubes, P2
Lowenthal, RM1
Jestrimski, KW1
Takahashi, T1
Palmeri, S1
Trave, F1
Russello, O1
Rustum, YM1
Singh, UP1
Ghose, R1
Ghose, AK1
Sodhi, A1
Singh, SM1
Singh, RK1
Love, RR1
Leventhal, H1
Easterling, DV1
Nerenz, DR1
Gorelik, E1
Ovejera, A1
Shoemaker, R1
Jarvis, A1
Alley, M1
Duff, R1
Mayo, J1
Herberman, R1
Boyd, M1
Kennedy, KA1
Wilmanns, W1
Binsack, T1
Sauer, H1
Marcovitch, S1
Keisari, Y1
Anselmo, AP1
Cimino, G1
Ruco, LP1
Biagini, C1
Uemura, T1
Amba, T1
Hamada, M1
Tanaka, S1
Tashima, CK1
Bergsagel, DE1
Reyes, P1
Hall, TC1
Moskalik, KG1
Kozlov, AP1
Akimov, AA1
Frei, E1
Schabel, FM1
Maruyama, Y1
Lee, TC1
Sullivan, S1
Morrone, G1
Ota, K2
Goldfinger, D1
McGinniss, MH1
Scherer, E1
Rassow, J1
Almersjö, O1
Bengmark, S1
Rudenstam, CM1
Hafström, L1
Nilsson, LA1
Vietti, T1
Eggerding, F1
Valeriote, F1
Klein, E1
Clarkson, B1
Ohkita, T1
O'Connor, A1
Benedeczky, I1

Reviews

9 reviews available for fluorouracil and Germinoblastoma

ArticleYear
Chemotherapy-induced takotsubo cardiomyopathy.
    Heart failure clinics, 2013, Volume: 9, Issue:2

    Topics: Antibodies, Monoclonal, Murine-Derived; Antimetabolites, Antineoplastic; Antineoplastic Agents; Echo

2013
[Cutaneous neoplasms].
    Praxis, 2003, Sep-03, Volume: 92, Issue:36

    Topics: Adjuvants, Immunologic; Aminoquinolines; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bio

2003
Paclitaxel pharmacology and other tumor types.
    Seminars in oncology, 1997, Volume: 24, Issue:6 Suppl 19

    Topics: Alkylating Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols

1997
Corticosteroid drugs: their role in oncological practice.
    The Medical journal of Australia, 1986, Jan-20, Volume: 144, Issue:2

    Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast

1986
Emulsion and activated carbon in cancer chemotherapy.
    Critical reviews in therapeutic drug carrier systems, 1986, Volume: 2, Issue:3

    Topics: Administration, Oral; Adult; Aged; Animals; Bleomycin; Breast Neoplasms; Carbon; Clinical Trials as

1986
An assessment of massive-dose chemotherapy of malignant disease.
    Canadian Medical Association journal, 1971, Jan-09, Volume: 104, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cell Division; Cyclo

1971
[Use of optical quantum generators (lasers) in oncology].
    Voprosy onkologii, 1972, Volume: 18, Issue:8

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma, Basal Cell; Carcinom

1972
[Cytostatic chemotherapy of neoplasms in children].
    La Pediatria, 1971, Volume: 79, Issue:1

    Topics: Adrenal Cortex Hormones; Aminopterin; Antineoplastic Agents; Asparaginase; Child; Child, Preschool;

1971
Multiple combination therapy in cancer chemotherapy in Japan.
    Gan, 1969, Volume: 60, Issue:3

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Chloroquine; Cyclophosphamide; Cytarabine; Drug

1969

Trials

6 trials available for fluorouracil and Germinoblastoma

ArticleYear
A Phase Ib multicenter, dose-escalation study of the polyamine analogue PG-11047 in combination with gemcitabine, docetaxel, bevacizumab, erlotinib, cisplatin, 5-fluorouracil, or sunitinib in patients with advanced solid tumors or lymphoma.
    Cancer chemotherapy and pharmacology, 2021, Volume: 87, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Cisplat

2021
Phase I study of eniluracil, oral 5-fluororacil and gemcitabine in patients with advanced malignancy.
    Investigational new drugs, 2002, Volume: 20, Issue:4

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Female; Fluorou

2002
[The so-called partial synchronization in the treatment of malignant lymphomas. A clinical study].
    Folia haematologica (Leipzig, Germany : 1928), 1980, Volume: 107, Issue:1

    Topics: Bleomycin; Cell Division; Clinical Trials as Topic; Cytarabine; Doxorubicin; Fluorouracil; Hodgkin D

1980
Delayed chemotherapy-induced nausea is augmented by high levels of endogenous noradrenaline.
    British journal of cancer, 1994, Volume: 70, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Circadian Rhythm; Cis

1994
F-MACHOP in advanced aggressive lymphoma.
    Leukemia & lymphoma, 1992, Volume: 7, Issue:3

    Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Do

1992
Emulsion and activated carbon in cancer chemotherapy.
    Critical reviews in therapeutic drug carrier systems, 1986, Volume: 2, Issue:3

    Topics: Administration, Oral; Adult; Aged; Animals; Bleomycin; Breast Neoplasms; Carbon; Clinical Trials as

1986

Other Studies

87 other studies available for fluorouracil and Germinoblastoma

ArticleYear
Synthesis and tumor inhibitory activity of novel coumarin analogs targeting angiogenesis and apoptosis.
    European journal of medicinal chemistry, 2014, Mar-21, Volume: 75

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Benzophenones; Carcinoma, Ehrlic

2014
Novel 3,5-bis(arylidene)-4-oxo-1-piperidinyl dimers: structure-activity relationships and potent antileukemic and antilymphoma cytotoxicity.
    European journal of medicinal chemistry, 2014, Apr-22, Volume: 77

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dimerization; Dose-Response

2014
Heat shock and HSP70 regulate 5-FU-mediated caspase-1 activation in myeloid-derived suppressor cells and tumor growth in mice.
    Journal for immunotherapy of cancer, 2020, Volume: 8, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Caspase 1; Enzyme Activation; Female; Fluorouracil; Heat-S

2020
[A Case of Malignant Lymphoma Undergoing HAI Treatment for Multiple Liver Metastases of Carcinoid That Appeared about Nine Years after Resection of Rectal Carcinoid with Liver Metastases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2020, Volume: 47, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Chemoembolization, Therapeuti

2020
Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism.
    Nucleic acids research, 2020, 12-16, Volume: 48, Issue:22

    Topics: Apoptosis; Cell Proliferation; Cisplatin; DNA Damage; Doxorubicin; Drug Resistance, Neoplasm; Etopos

2020
Differential effects of low-dose fludarabine or 5-fluorouracil on the tumor growth and myeloid derived immunosuppression status of tumor-bearing mice.
    International immunopharmacology, 2017, Volume: 47

    Topics: Animals; Antineoplastic Agents; Carcinogenesis; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocyt

2017
Mathematical modeling of tumor-induced immunosuppression by myeloid-derived suppressor cells: Implications for therapeutic targeting strategies.
    Journal of theoretical biology, 2018, 04-07, Volume: 442

    Topics: Algorithms; Animals; Antineoplastic Agents; Arginine; Fluorouracil; Humans; Immune Tolerance; Immuni

2018
Vinorelbine, cyclophosphamide and 5-FU effects on the circulating and intratumoural landscape of immune cells improve anti-PD-L1 efficacy in preclinical models of breast cancer and lymphoma.
    British journal of cancer, 2018, Volume: 118, Issue:10

    Topics: Animals; B7-H1 Antigen; Breast Neoplasms; Cell Line, Tumor; Cyclophosphamide; Fluorouracil; Humans;

2018
Encapsulation and Systemic Delivery of 5-Fluorouracil Conjugated with Silkworm Pupa Derived Protein Nanoparticles for Experimental Lymphoma Cancer.
    Bioconjugate chemistry, 2018, 09-19, Volume: 29, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Biocompatible Materials; Bombyx; Cell Line, Tumor; Cell Pr

2018
Suppressive effects of low-dose 5-fluorouracil, busulfan or treosulfan on the expansion of circulatory neutrophils and myeloid derived immunosuppressor cells in tumor-bearing mice.
    International immunopharmacology, 2016, Volume: 40

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined

2016
Survival of mice bearing a transplanted syngeneic lymphoma following treatment with cyclophosphamide, 5-fluorouracil, or 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Journal of the National Cancer Institute, 1967, Volume: 39, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Female; Fluor

1967
Avemar, a nontoxic fermented wheat germ extract, attenuates the growth of sensitive and 5-FdUrd/Ara-C cross-resistant H9 human lymphoma cells through induction of apoptosis.
    Oncology reports, 2009, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cytarabine; Dose

2009
Variations in the content of CD34+ cells in the peripheral blood of cancer patients receiving out-patient chemotherapy.
    Cytotherapy, 1999, Volume: 1, Issue:1

    Topics: Adolescent; Adult; Aged; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Breast Neop

1999
Effect of Indigofera aspalathoides against Dalton's ascitic lymphoma.
    Fitoterapia, 2003, Volume: 74, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Ascites; Fluorouracil; Indigofera; Injections, Intraperi

2003
Customized mitogen or antibody treatments enhance the sensitivity of lymphoid tumors to 5-fluorouracil in vitro and in vivo.
    Leukemia & lymphoma, 2003, Volume: 44, Issue:5

    Topics: Animals; Antibodies, Monoclonal; CD40 Antigens; Cell Division; Cell Membrane; Drug Synergism; Fluoro

2003
Effects of arsenic-azoproteins on mouse lymphoma cells in vivo; with observations on the effects of other anti-lymphoma agents, and on the susceptibility to these effects of lymphoma cells of various types.
    The Journal of experimental medicine, 1958, Nov-01, Volume: 108, Issue:5

    Topics: Animals; Antineoplastic Agents; Arsenic; Arsenicals; Fluorouracil; Guinea Pigs; Lymphoma; Mice; Neop

1958
Effect of steroids and fluoropyrimidines on lymphomas. II. In vivo studies on tumor resistance and collateral sensitivity.
    Cancer research, 1963, Volume: 23

    Topics: Antimetabolites; DNA; DNA, Neoplasm; Fludrocortisone; Fluorouracil; Humans; Lymphoma; RNA; RNA, Neop

1963
Characterization of resistance to amethopterin, 8-azaguanine and several fluorinated pyrimidines in the murine lymphocytic neoplasm, P388.
    Journal of cellular and comparative physiology, 1962, Volume: 60

    Topics: Animals; Antineoplastic Agents; Azaguanine; Fluorouracil; Leukemia; Leukemia, Lymphoid; Lymphoma; Me

1962
EFFECT OF CORTICOSTEROIDS ON RIBONUCLEASE AND NUCLEIC ACID CONTENT IN LYMPHOSARCOMA P1798.
    Cancer research, 1963, Volume: 23

    Topics: Adrenal Cortex Hormones; Animals; Edetic Acid; Fluorouracil; Glucocorticoids; Lymphoma; Lymphoma, No

1963
STUDIES ON TUMOR RESISTANCE TO 5-FLUOROURACIL.
    Cancer research, 1963, Volume: 23

    Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Fluorouracil; Genetics; Lymphoma; Lymphoma, Non-Hodgkin; M

1963
GROWTH INHIBITION OF A SPECTRUM OF TRANSPLANTED MOUSE TUMORS BY COMBINATIONS OF INHIBITORS OF NUCLEIC ACID BIOSYNTHESIS AND ALKYLATING AGENTS.
    Cancer research, 1963, Volume: 23

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Azaguanine; Azaserine; Carcinoma, Ehrlich Tumor;

1963
EXPERIENCE WITH CHEMOTHERAPY OF CANCER AT THE UNIVERSITY OF PRETORIA.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Antineoplastic Agents; Aziridines; Breast Neoplasms; Cyclophosphamide; Dactinomycin; Fluorouracil; H

1964
NONSURGICAL TREATMENT OF PULMONARY CANCER.
    Modern treatment, 1964, Volume: 1

    Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agen

1964
TREATMENT OF MALIGNANT TUMOURS WITH 5-FLUOROURACIL IN 80 PATIENTS.
    Acta radiologica: therapy, physics, biology, 1964, Volume: 2

    Topics: Biomedical Research; Breast Neoplasms; Colonic Neoplasms; Drug Therapy; Esophageal Neoplasms; Female

1964
CHEMOTHERAPY OF MALIGNANCIES OF THE GASTROINTESTINAL TRACT.
    American journal of surgery, 1965, Volume: 109

    Topics: Antineoplastic Agents; Carcinoid Tumor; Colonic Neoplasms; Cyclophosphamide; Fluorouracil; Gastroint

1965
REGIONAL ARTERIAL INFUSION OF ANTIMETABOLITES. AN ANALYSIS OF THE RESULTS OBTAINED IN 33 PATIENTS WITH MALIGNANT TUMORS OF THE HEAD AND NECK.
    The Journal of surgical research, 1965, Volume: 5

    Topics: Antimetabolites; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; H

1965
Influence of keratinocyte growth factor on clonal growth of epithelial tumor cells, lymphoma and leukemia cells and on sensitivity of tumor cells towards 5-fluorouracil in vitro.
    International journal of oncology, 2004, Volume: 25, Issue:4

    Topics: Cell Differentiation; Cell Division; Cell Line, Tumor; Fibroblast Growth Factor 7; Fibroblast Growth

2004
Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs.
    Journal of the National Cancer Institute, 2004, Nov-17, Volume: 96, Issue:22

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Animals; Antineoplastic Agents; Benzimidazo

2004
Cytotoxic and apoptotic effects of novel heterodinucleoside phosphates consisting of 5-fluorodeoxyuridine and Ara-C in human cancer cell lines.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Bisbenzimidazole; Cell Line, Tumor; Colonic Neoplasms; C

2004
5-fluorouracil-based chemotherapy enhances the antitumor activity of a thymidylate synthase-directed polyepitopic peptide vaccine.
    Journal of the National Cancer Institute, 2005, Oct-05, Volume: 97, Issue:19

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neo

2005
Linear quadratic modeling of increased late normal-tissue effects in special clinical situations.
    International journal of radiation oncology, biology, physics, 2006, Mar-01, Volume: 64, Issue:3

    Topics: Aged; Algorithms; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosph

2006
[Study of the immunological mechanism of anti-tumor effects of 5-FU by establishing EL4 tumor-bearing mouse models].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2007, Volume: 23, Issue:11

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship

2007
[Relationships between tumor shrinkage and peripheral blood cell changes during tumor-rejection induced by a high dose of 5-FU in C57BL/6 mice].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2008, Volume: 24, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Blood Platelets; Cell Line, Tumor; Disease Models, Animal;

2008
A model system for examining the action of anti-cancer agents at the cellular level in vivo.
    National Cancer Institute monograph, 1967, Volume: 24

    Topics: Animals; Antineoplastic Agents; Azaserine; Cyclophosphamide; Dactinomycin; Fluorouracil; Hematopoies

1967
Comparison of the sensitivity of hematopoietic colony-forming cells in different proliferative states to 5-fluorouracil.
    Journal of the National Cancer Institute, 1967, Volume: 38, Issue:3

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Fluorouracil; Hematopoietic System; Lymphoma; Mice

1967
Sensitivity of L cells in exponential and stationary phase to 5-fluorouracil.
    Nature, 1967, Jul-15, Volume: 215, Issue:5098

    Topics: Animals; Culture Techniques; Fluorouracil; L Cells; Leukemia, Experimental; Lymphoma; Mice; Mitosis

1967
[Clinical evaluation on the sensitivity test for anti-cancer agents in malignant bone and soft-tissue tumors].
    Gan no rinsho. Japan journal of cancer clinics, 1984, Volume: 30, Issue:9 Suppl

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide;

1984
Combination chemotherapy for advanced cutaneous T-cell lymphomas.
    Cancer treatment reports, 1980, Volume: 64, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Therapy, Combination; Female; Fluor

1980
Combined effects of 5-fluorouracil and interferon on proliferation of human neoplastic cells in culture.
    Gan, 1982, Volume: 73, Issue:5

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Drug Evaluation, Preclinical; Fibroblasts; Fluo

1982
[Combination chemotherapy of brain tumors with ACNU and 5-FU].
    Neurologia medico-chirurgica, 1983, Volume: 23, Issue:8

    Topics: Astrocytoma; Biological Products; Brain Neoplasms; Combined Modality Therapy; Drug Therapy, Combinat

1983
[Effect of cepharanthin on peripheral leukocytopenia caused by antineoplastic agents].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:4 Pt 2

    Topics: Alkaloids; Animals; Benzylisoquinolines; Fluorouracil; Leukopenia; Lymphoma; Mice; Mice, Inbred Stra

1983
Regulation of RNA- and DNA-directed actions of 5-fluoropyrimidines in mouse T-lymphoma (S-49) cells.
    Cancer research, 1980, Volume: 40, Issue:11

    Topics: Animals; Cell Cycle; DNA, Neoplasm; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Leu

1980
Biochemical phenotype of 5-fluorouracil-resistant murine T-lymphoblasts with genetically altered CTP synthetase activity.
    The Journal of biological chemistry, 1984, Jul-25, Volume: 259, Issue:14

    Topics: Animals; Carbon-Nitrogen Ligases; Cell Division; Cell Line; Clone Cells; Deoxyribonucleotides; Drug

1984
The natural history of gastric cancer and prognostic factors influencing survival.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Female; Fluorouracil; Gastrectomy; Humans; Liver Neoplasms; Lymphatic M

1984
Combined effect of levan and cytotoxic agents on the growth of experimental tumours in mice.
    British journal of experimental pathology, 1983, Volume: 64, Issue:3

    Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Co

1983
In vivo rates of pyrimidine nucleotide metabolism in intact mouse T-lymphoma (s-49) cells treated with 5-fluorouracil.
    The Journal of biological chemistry, 1981, Mar-10, Volume: 256, Issue:5

    Topics: Animals; Cell Line; Deoxyribonucleotides; DNA, Neoplasm; Fluorouracil; Kinetics; Lymphoma; Mathemati

1981
Immunopotentiation of anticancer chemotherapy by Candida albicans, other yeasts and insoluble glucan in an experimental lymphoma model.
    Sabouraudia, 1982, Volume: 20, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; Candida albicans; Carmustine; Cell Wall; Cry

1982
[Non-surgically treated primary malignant lymphoma of the brain: recurrences in 2 occasions following the cessations of antineoplastic agent administration].
    Nihon Gan Chiryo Gakkai shi, 1982, Feb-20, Volume: 17, Issue:1

    Topics: Aged; Brain Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphoma; Mitomycins

1982
Non-invasive methods for detection of cardiomyopathy in the course of antineoplastic treatment.
    Neoplasma, 1982, Volume: 29, Issue:3

    Topics: Antineoplastic Agents; Breast Neoplasms; Cardiomyopathies; Doxorubicin; Drug Therapy, Combination; F

1982
[Further study of immunopotentiation in experimental antiblastic therapy by inactivated yeasts and glucan].
    Annali dell'Istituto superiore di sanita, 1982, Volume: 18, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Carmustine; Combined Modality Therapy; Female; Fluorouracil; Glucan

1982
Influence of duration of exposure to 5-fluorouracil on antiproliferating activity against cultured murine lymphoma cells.
    British journal of cancer, 1981, Volume: 44, Issue:5

    Topics: Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Fluorouracil; Lymphoma; M

1981
Combination clinical trials with thymidine and fluorouracil: a phase I and clinical pharmacologic evaluation.
    Cancer, 1980, Mar-15, Volume: 45, Issue:5 Suppl

    Topics: Adult; Aged; Bone Marrow; Colonic Neoplasms; Drug Evaluation; Drug Therapy, Combination; Female; Flu

1980
ABL oncogenes directly stimulate two distinct target cells in bone marrow from 5-fluorouracil-treated mice.
    Oncogene, 1993, Volume: 8, Issue:5

    Topics: Animals; Base Sequence; Bone Marrow; Cell Transformation, Neoplastic; Fluorouracil; Fusion Proteins,

1993
Minimal toxicity to myeloid progenitor cells of weekly 24-hr infusion of high-dose 5-fluorouracil: direct evidence from colony forming unit-granulocyte and monocyte (CFU-GM) clonogenic assay.
    Pharmacology & toxicology, 2000, Volume: 86, Issue:3

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Breast Neoplasms; Colony-Forming Units Assay; Do

2000
Expression of Escherichia coli uracil phosphoribosyltransferase gene in murine colon carcinoma cells augments the antitumoral effect of 5-fluorouracil and induces protective immunity.
    Cancer gene therapy, 2000, Volume: 7, Issue:4

    Topics: Adenocarcinoma; Animals; Cell Survival; Colonic Neoplasms; Escherichia coli; Fluorouracil; Lymphoma;

2000
Pharmacokinetics and toxicity of intravitreal chemotherapy for primary intraocular lymphoma.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2001, Volume: 119, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Chromatography, Hi

2001
Pyrimidine pathway variants of cultured mouse lymphoma cells with altered levels of both orotate phosphoribosyltransferase and orotidylate decarboxylase.
    The Journal of biological chemistry, 1979, Jun-10, Volume: 254, Issue:11

    Topics: Animals; Azauridine; Carboxy-Lyases; Cell Division; Cell Line; Fluorouracil; Kinetics; Lymphoma; Mic

1979
Studies of the growth of an ascitic tumour. II. A system to study the tumour-age dependent effect of antitumour agents.
    European journal of cancer, 1978, Volume: 14, Issue:1

    Topics: Alkylating Agents; Animals; Cell Division; Depression, Chemical; Dose-Response Relationship, Drug; F

1978
Changes of the immunogenic properties of a radiation-induced mouse lymphoma following treatment with antitumor drugs.
    Cancer research, 1975, Volume: 35, Issue:8

    Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Cyclophosphamide; Dacarbazine; Fluorouracil; His

1975
[Nephrotic syndrome associated with neoplasms and malignant lymphoma].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Jan-10, Volume: 81, Issue:1

    Topics: Adult; Aged; Cyclophosphamide; Female; Fluorouracil; Humans; Lymphoma; Male; Middle Aged; Mitomycin;

1992
Effects of 1-(halogenalkoxy)alkyl-5-fluorouracil derivatives on cell growth, cell volume and nucleus size of mouse lymphoma cells.
    Chemotherapy, 1992, Volume: 38, Issue:1

    Topics: Animals; Cell Division; Cell Nucleus; Fluorouracil; Lymphoma; Mice; Tumor Cells, Cultured

1992
[Analysis of tumor cell growth and effects of antitumor drugs on cell cycle regulation by flow cytometry].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:12

    Topics: Animals; Cell Cycle; Cell Division; Cisplatin; Flow Cytometry; Fluorouracil; Interphase; Lymphoma; M

1991
[Extraskeletal pharyngolaryngeal Ewing's sarcoma. Apropos of a case].
    Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris, 1991, Volume: 108, Issue:1

    Topics: Adult; Cisplatin; Combined Modality Therapy; Diagnosis, Differential; Fluorouracil; Humans; Immunohi

1991
Enhancement by uridine of the anabolism of 5-fluorouracil in mouse T-lymphoma (S-49) cells.
    Cancer research, 1985, Volume: 45, Issue:9

    Topics: Animals; Cell Survival; Cells, Cultured; DNA; Fluorouracil; Lymphoma; Mice; Phosphoribosyl Pyrophosp

1985
The role of drug sequence in therapeutic selectivity of the combination of 5-fluorouracil and cis-platin.
    Selective cancer therapeutics, 1989,Winter, Volume: 5, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Dose-Response

1989
The effect of histidine on the structure and antitumor activity of metal-5-halouracil complexes.
    Journal of inorganic biochemistry, 1989, Volume: 37, Issue:4

    Topics: Animals; Bromouracil; Cadmium; Cobalt; Copper; Fluorouracil; Histidine; Lymphoma; Magnetics; Mangane

1989
Side effects and emotional distress during cancer chemotherapy.
    Cancer, 1989, Feb-01, Volume: 63, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxor

1989
Determination of 5-fluorouridine diphosphate glucose as a metabolite of 5-fluorouracil in mouse T-lymphoma (S-49) cells using high-performance liquid chromatography.
    Journal of chromatography, 1986, Apr-18, Volume: 356, Issue:3

    Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Deoxyuracil Nucleotides; Fluorodeoxy

1986
Microencapsulated tumor assay: new short-term assay for in vivo evaluation of the effects of anticancer drugs on human tumor cell lines.
    Cancer research, 1987, Nov-01, Volume: 47, Issue:21

    Topics: Animals; Cyclophosphamide; Doxorubicin; Drug Screening Assays, Antitumor; Female; Fluorouracil; Huma

1987
Mammalian mutants genetically altered in CTP synthetase activity.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: Animals; Biological Transport; Carbon-Nitrogen Ligases; Cell Cycle; Cell Line; Cytidine Triphosphate

1986
Dissociation of 5-fluorouracil-induced DNA fragmentation from either its incorporation into DNA or its cytotoxicity in murine T-lymphoma (S-49) cells.
    Cancer research, 1987, Feb-15, Volume: 47, Issue:4

    Topics: Animals; Cell Survival; Chromatography, High Pressure Liquid; Colony-Forming Units Assay; Crotalid V

1987
[Cytostatic polychemotherapy in the aged].
    Deutsche medizinische Wochenschrift (1946), 1985, Dec-20, Volume: 110, Issue:51-52

    Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dac

1985
The synergistic tumoricidal activity of anticancer drugs and oxidative burst-triggered macrophages.
    Cancer immunology, immunotherapy : CII, 1985, Volume: 20, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Cell Survival; Cytotoxicity, Immunologic; Dactinomycin; Dose-R

1985
Treatment of diffuse aggressive non-Hodgkin's lymphomas with an intensive multi-drug regimen including high-dose cytosine arabinoside (F-MACHOP).
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Adolescent; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide

1985
[Treatment of terminal cancer and relapsed cancer by 5-5-FU(5-fluorouracil)].
    Gan no rinsho. Japan journal of cancer clinics, 1968, Volume: 14, Issue:7

    Topics: Adult; Aged; Breast Neoplasms; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Lymphoma; M

1968
Hypercalcemia in cancer: response to therapy.
    American family physician, 1974, Volume: 10, Issue:5

    Topics: Adenocarcinoma; Adult; Allopurinol; Antineoplastic Agents; Calcium; Cyclophosphamide; Fluorouracil;

1974
Synthesis of 5-fluorouridine 5'-phosphate by a pyrimidine phosphoribosyltransferase of mammalian origin. II. Correlation between the tumor levels of the enzyme and the 5-fluorouracil-promoted increase in survival of tumor-bearing mice.
    Biochemical pharmacology, 1969, Volume: 18, Issue:10

    Topics: Animals; Fluorouracil; Leukemia L1210; Lymphoma; Mice; Neoplasm Transplantation; Neoplasms, Experime

1969
Comparative chemotherapy of AKR lymphoma and human hematological neoplasia.
    Cancer research, 1974, Volume: 34, Issue:1

    Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytara

1974
Age cohort variation of tumor cells.
    Radiology, 1973, Volume: 109, Issue:1

    Topics: Animals; Cell Division; Disease Models, Animal; DNA, Neoplasm; Fluorouracil; Hydroxyurea; Lymphoma;

1973
Advanced cancer: New concepts of medical therapy.
    Geriatrics, 1973, Volume: 28, Issue:11

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Choriocarcinoma; Colonic Neopl

1973
Rh-incompatible platelet transfusions--risks and consequences of sensitizing immunosuppressed patients.
    The New England journal of medicine, 1971, Apr-29, Volume: 284, Issue:17

    Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antibodies; Antibody Formation; Blood Group Incompatibili

1971
[Basic principles of percutaneous radiotherapy in cervical lymph node metastases].
    Strahlentherapie, 1971, Volume: 141, Issue:5

    Topics: Carcinoma, Squamous Cell; Cesium Isotopes; Cobalt Isotopes; Electrons; Fluorouracil; Head and Neck N

1971
Evaluation of hepatic dearterialization in primary and secondary cancer of the liver.
    American journal of surgery, 1972, Volume: 124, Issue:1

    Topics: Adult; Aged; Female; Fluorouracil; Hepatic Artery; Humans; Ligation; Liver; Liver Neoplasms; Lymphom

1972
Combined effect of x radiation and 5-fluorouracil on survival of transplanted leukemic cells.
    Journal of the National Cancer Institute, 1971, Volume: 47, Issue:4

    Topics: Animals; Bone Marrow Cells; Cell Line; Cell Survival; Clone Cells; Fluorouracil; In Vitro Techniques

1971
Local chemotherapy of cutaneous neoplasms.
    Proceedings. National Cancer Conference, 1970, Volume: 6

    Topics: Adenocarcinoma; Allergy and Immunology; Antineoplastic Agents; Carcinoma, Squamous Cell; Dactinomyci

1970
Kinetics of proliferation of cancer cells in neoplastic effusions in man.
    Cancer, 1965, Volume: 18, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Agents; Autoradiography; Cell Division; DNA, Neoplasm; Exudates and T

1965
Antimetabolite-induced changes in the fine structure of tumour cells.
    Acta biologica Academiae Scientiarum Hungaricae, 1966, Volume: 17, Issue:2

    Topics: Animals; Ascites; Fluorouracil; Lymphoma; Mice; Microscopy, Electron

1966