fluorouracil has been researched along with Genital Neoplasms, Male in 24 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Genital Neoplasms, Male: Tumor or cancer of the MALE GENITALIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "25 patients (2 females, 23 males, 20 to 40-year-old) suffering from condylomata acuminata (19 genital, 2 anal, and 4 genitoanal lesions) were locally treated with salicylic acid containing 5-fluorouracil (Verrumal) once a day." | 7.67 | [5-Fluorouracil treatment of condylomata acuminata]. ( Djawari, D, 1986) |
| "Sixty-two females and 21 males were treated for recurrent HPV infection, with either fluorouracil (Efudex 5%) cream or laser ablation of the lesions." | 5.08 | Interferon as an adjuvant treatment for genital condyloma acuminatum. ( Bergman, A; Klutke, JJ, 1995) |
| "In order to treat a patient with extramammary Paget's disease who had multiple metastases, 500 mg/day of 5-fluorouracil (7 days per week) and 5 mg/day of cisplatin (5 days per week) were administrated intravenously for 24 hours and 1 hour, respectively." | 3.72 | Trial of low-dose 5-fluorouracil/cisplatin therapy for advanced extramammary Paget's disease. ( Kariya, K; Schwartz, RA; Tsuji, T, 2004) |
| "25 patients (2 females, 23 males, 20 to 40-year-old) suffering from condylomata acuminata (19 genital, 2 anal, and 4 genitoanal lesions) were locally treated with salicylic acid containing 5-fluorouracil (Verrumal) once a day." | 3.67 | [5-Fluorouracil treatment of condylomata acuminata]. ( Djawari, D, 1986) |
| "A patient was diagnosed by biopsy and treated for squamous cell carcinoma in situ of the scrotum." | 2.38 | Paget's disease of the scrotum: a case report and review of current literature. ( Boman, DA; Dudrey, EF; Moliver, CL; Morales, CA; Reedy, MB, 1991) |
| "Metastatic penoscrotal extramammary Paget's disease (EMPD) has seldom been reported in the literature." | 1.35 | Clinicopathological characteristics, management and outcome of metastatic penoscrotal extramammary Paget's disease. ( Dai, B; Mao, HR; Shen, YJ; Yao, XD; Ye, DW; Zhang, HL; Zhang, SL; Zhu, Y, 2009) |
| "A goblet cell carcinoid of the vermiform appendix was identified as the primary tumor." | 1.35 | [Metastazation into the seminal vesicles due to primary goblet cell carcinoid of the vermiform appendix. An unusual diagnostic procedure of a seminal vesicle tumor]. ( Flury, R; Gramann, T; Jaeger, P; Matter, L; Pfofe, D, 2009) |
| "The true extent of the skin affected in extramammary Paget's disease is frequently well beyond its clinical borders." | 1.27 | Role of preoperative topical 5-fluorouracil in preparation for Mohs micrographic surgery of extramammary Paget's disease. ( Eliezri, YD; Horan, DB; Silvers, DN, 1987) |
| "In a 74-year-old man extramammary Paget's disease of the scrotal and perianal areas masqueraded as tinea cruris and chronic dermatitis for 7 years before it was diagnosed." | 1.26 | Extramammary Paget's disease. ( Goodall, J; Haberman, HF; Llewellyn, M, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (45.83) | 18.7374 |
| 1990's | 6 (25.00) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 3 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lal, H | 1 |
| Yadav, P | 1 |
| Jena, R | 1 |
| Jain, M | 1 |
| Guindalini, RS | 1 |
| Mak, MP | 1 |
| Takahashi, TK | 1 |
| Testa, L | 1 |
| Dzik, C | 1 |
| Oashi, K | 1 |
| Tsutsumida, A | 1 |
| Namikawa, K | 1 |
| Tanaka, R | 1 |
| Omata, W | 1 |
| Yamamoto, Y | 1 |
| Yamazaki, N | 1 |
| Zhu, Y | 1 |
| Ye, DW | 1 |
| Yao, XD | 1 |
| Zhang, SL | 1 |
| Dai, B | 1 |
| Zhang, HL | 1 |
| Shen, YJ | 1 |
| Mao, HR | 1 |
| Gramann, T | 1 |
| Matter, L | 1 |
| Pfofe, D | 1 |
| Flury, R | 1 |
| Jaeger, P | 1 |
| Kariya, K | 1 |
| Tsuji, T | 1 |
| Schwartz, RA | 1 |
| Ye, JN | 1 |
| Rhew, DC | 1 |
| Yip, F | 1 |
| Edelstein, L | 1 |
| Kumar, AA | 1 |
| Klutke, JJ | 1 |
| Bergman, A | 2 |
| Bewley, AP | 1 |
| Bracka, A | 1 |
| Staughton, RC | 1 |
| Bunker, CB | 1 |
| Haberman, HF | 1 |
| Goodall, J | 1 |
| Llewellyn, M | 1 |
| Pareek, S | 1 |
| Reedy, MB | 1 |
| Morales, CA | 1 |
| Moliver, CL | 1 |
| Dudrey, EF | 1 |
| Boman, DA | 1 |
| Epperson, WJ | 1 |
| Nalick, R | 1 |
| Thivolet, J | 2 |
| Silva, PD | 1 |
| Micha, JP | 1 |
| Silva, DG | 1 |
| Thomas, L | 1 |
| Erpenbach, K | 1 |
| Derschum, W | 1 |
| von Vietsch, H | 1 |
| Reis, M | 1 |
| Eliezri, YD | 1 |
| Silvers, DN | 1 |
| Horan, DB | 1 |
| Krebs, HB | 1 |
| Djawari, D | 1 |
| Stringel, G | 1 |
| Spence, J | 1 |
| Corsini, L | 1 |
3 reviews available for fluorouracil and Genital Neoplasms, Male
| Article | Year |
|---|---|
Extramammary Paget's disease resistant to surgery and imiquimod monotherapy but responsive to imiquimod combination topical chemotherapy with 5-fluorouracil and retinoic acid: a case report.
Topics: Administration, Cutaneous; Aged; Aminoquinolines; Antineoplastic Combined Chemotherapy Protocols; Di | 2006 |
Paget's disease of the scrotum: a case report and review of current literature.
Topics: Carcinoma in Situ; Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; Genital Neopla | 1991 |
[Treatment of genital warts and condyloma].
Topics: Antiviral Agents; Bleomycin; Condylomata Acuminata; Cryosurgery; Dinitrofluorobenzene; Electrocoagul | 1988 |
3 trials available for fluorouracil and Genital Neoplasms, Male
| Article | Year |
|---|---|
Interferon as an adjuvant treatment for genital condyloma acuminatum.
Topics: Adolescent; Adult; Combined Modality Therapy; Condylomata Acuminata; Female; Fluorouracil; Genital N | 1995 |
Management of condyloma acuminatum.
Topics: Clinical Trials as Topic; Condylomata Acuminata; Cryosurgery; Electrocoagulation; Female; Fluorourac | 1985 |
[Adjuvant 5-fluorouracil lacquer administration for reducing the rate of recurrence of condylomata acuminata following laser surgery treatment].
Topics: Adult; Combined Modality Therapy; Condylomata Acuminata; Fluorouracil; Genital Neoplasms, Male; Huma | 1989 |
18 other studies available for fluorouracil and Genital Neoplasms, Male
| Article | Year |
|---|---|
Metastatic primary seminal vesicle adenocarcinoma: management of a rare tumour with multiagent chemotherapy and hormonal therapy.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Genital Neoplasms, Mal | 2017 |
Multiagent chemotherapy for metastatic adenocarcinoma of the seminal vesicle.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Genital Neoplasms, Mal | 2014 |
Combination chemotherapy for metastatic extramammary Paget disease.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bone Neopla | 2014 |
Clinicopathological characteristics, management and outcome of metastatic penoscrotal extramammary Paget's disease.
Topics: Aged; Antineoplastic Agents; Biomarkers, Tumor; Cadherins; Docetaxel; Female; Fluorouracil; Genital | 2009 |
[Metastazation into the seminal vesicles due to primary goblet cell carcinoid of the vermiform appendix. An unusual diagnostic procedure of a seminal vesicle tumor].
Topics: Antineoplastic Combined Chemotherapy Protocols; Appendectomy; Appendiceal Neoplasms; Appendix; Bioma | 2009 |
Trial of low-dose 5-fluorouracil/cisplatin therapy for advanced extramammary Paget's disease.
Topics: Aged; Antineoplastic Agents; Cisplatin; Fatal Outcome; Fluorouracil; Genital Neoplasms, Male; Humans | 2004 |
Topical 5-FU helpful in reducing the rate of recurrence of condylomata acuminata.
Topics: Condylomata Acuminata; Female; Fluorouracil; Genital Neoplasms, Female; Genital Neoplasms, Male; Hum | 1982 |
Extramammary Paget's disease of the scrotum: treatment with topical 5-fluorouracil and plastic surgery.
Topics: Aged; Combined Modality Therapy; Fluorouracil; Genital Neoplasms, Male; Humans; Male; Paget Disease, | 1994 |
Extramammary Paget's disease.
Topics: Aged; Anus Neoplasms; Fluorouracil; Genital Neoplasms, Male; Humans; Male; Paget Disease, Extramamma | 1978 |
Treatment of condyloma acuminatum with 5% 5-fluorouracil.
Topics: Adolescent; Adult; Condylomata Acuminata; Fluorouracil; Genital Neoplasms, Male; Humans; Male | 1979 |
Androscopy for anogenital HPV.
Topics: Acetates; Acetic Acid; Adult; Anus Neoplasms; Cryosurgery; Female; Fluorouracil; Genital Neoplasms, | 1991 |
Genital human papillomavirus infection in men. Diagnosis and treatment with a laser and 5-fluorouracil.
Topics: Acetates; Acetic Acid; Administration, Topical; Adult; Colposcopy; Combined Modality Therapy; Condyl | 1991 |
[Treatment of condylomata acuminata].
Topics: Condylomata Acuminata; Female; Fluorouracil; Genital Neoplasms, Female; Genital Neoplasms, Male; Hum | 1990 |
Role of preoperative topical 5-fluorouracil in preparation for Mohs micrographic surgery of extramammary Paget's disease.
Topics: Aged; Biopsy; Fluorouracil; Genital Neoplasms, Male; Humans; Male; Paget Disease, Extramammary; Preo | 1987 |
Management of human papillomavirus-associated genital lesions in men.
Topics: Adolescent; Adult; Combined Modality Therapy; Condylomata Acuminata; Cryosurgery; Fluorouracil; Geni | 1989 |
Interferon for treatment of genital warts.
Topics: Condylomata Acuminata; Cryosurgery; Electrocoagulation; Female; Fluorouracil; Genital Neoplasms, Fem | 1988 |
[5-Fluorouracil treatment of condylomata acuminata].
Topics: Administration, Topical; Adult; Condylomata Acuminata; Female; Fluorouracil; Genital Neoplasms, Fema | 1986 |
Genital warts in children.
Topics: Adolescent; Child; Child, Preschool; Condylomata Acuminata; Electrocoagulation; Female; Fluorouracil | 1985 |