fluorouracil has been researched along with Genital Neoplasms, Female in 55 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Genital Neoplasms, Female: Tumor or cancer of the female reproductive tract (GENITALIA, FEMALE).
| Excerpt | Relevance | Reference |
|---|---|---|
| " We evaluated the efficacy of a combined antibiotic regimen of monobactam (aztreonam) and antipseudomonal penicillin (piperacillin) in treating neutropenic fever episodes in gynecologic-oncology patients receiving cisplatin-based chemotherapy." | 7.70 | Aztreonam plus piperacillin--empiric treatment of neutropenic fever in gynecology-oncology patients receiving cisplatin-based chemotherapy. ( Altaras, M; Beyth, Y; Chowers, M; Fishman, A; Lang, R, 1998) |
| "25 patients (2 females, 23 males, 20 to 40-year-old) suffering from condylomata acuminata (19 genital, 2 anal, and 4 genitoanal lesions) were locally treated with salicylic acid containing 5-fluorouracil (Verrumal) once a day." | 7.67 | [5-Fluorouracil treatment of condylomata acuminata]. ( Djawari, D, 1986) |
| "Sixty-two females and 21 males were treated for recurrent HPV infection, with either fluorouracil (Efudex 5%) cream or laser ablation of the lesions." | 5.08 | Interferon as an adjuvant treatment for genital condyloma acuminatum. ( Bergman, A; Klutke, JJ, 1995) |
| "A randomized control trial study was carried out to evaluate the effect of allopurinol mouth wash on stomatitis induced by chemotherapy in gynecologic patients." | 5.06 | [Prevention of stomatitis induced by anti-cancer drugs]. ( Dozono, H; Ishibashi, M; Miwa, K; Motoya, T; Nagata, Y; Nakamura, K; Nakamura, S; Shinmura, R, 1989) |
| " We evaluated the efficacy of a combined antibiotic regimen of monobactam (aztreonam) and antipseudomonal penicillin (piperacillin) in treating neutropenic fever episodes in gynecologic-oncology patients receiving cisplatin-based chemotherapy." | 3.70 | Aztreonam plus piperacillin--empiric treatment of neutropenic fever in gynecology-oncology patients receiving cisplatin-based chemotherapy. ( Altaras, M; Beyth, Y; Chowers, M; Fishman, A; Lang, R, 1998) |
| "25 patients (2 females, 23 males, 20 to 40-year-old) suffering from condylomata acuminata (19 genital, 2 anal, and 4 genitoanal lesions) were locally treated with salicylic acid containing 5-fluorouracil (Verrumal) once a day." | 3.67 | [5-Fluorouracil treatment of condylomata acuminata]. ( Djawari, D, 1986) |
| " The average half-life of HCFUf and 5-FUra were 1." | 1.27 | [The determination of thymidylate synthetase inhibition for testing fluoropyrimidines--pharmacokinetics and metabolism of carmofur (HCFU) in patients with gynecologic malignancies--Tokai HCFU Study Group for Gynecologic Malignancies]. ( Hori, M; Kano, T; Mizuno, K; Nishida, Y; Ohta, M; Okamoto, E; Sakakibara, K; Tokuhashi, Y; Tomita, Y; Yoshio, G, 1986) |
| "Generally, metastases responded better than the advanced primaries from which they were derived, except for those from breast tumours." | 1.25 | The influence of site of metastasis on tumour growth and response to chemotherapy. ( Bross, ID; Slack, NH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (69.09) | 18.7374 |
| 1990's | 9 (16.36) | 18.2507 |
| 2000's | 4 (7.27) | 29.6817 |
| 2010's | 4 (7.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bazan, JG | 1 |
| Luxton, G | 1 |
| Kozak, MM | 1 |
| Anderson, EM | 1 |
| Hancock, SL | 1 |
| Kapp, DS | 1 |
| Kidd, EA | 1 |
| Koong, AC | 1 |
| Chang, DT | 1 |
| Itoh, Y | 2 |
| Ikeda, M | 1 |
| Hirasawa, N | 2 |
| Okuda, T | 2 |
| Murao, T | 1 |
| Kubota, S | 1 |
| Okada, T | 1 |
| Naganawa, S | 1 |
| Ishigaki, T | 2 |
| Paumier, A | 1 |
| Le Péchoux, C | 1 |
| Barrick, B | 1 |
| Matthys, B | 1 |
| Fraga, G | 1 |
| O'Toole, SA | 1 |
| Sheppard, BL | 1 |
| McGuinness, EP | 1 |
| Gleeson, NC | 1 |
| Yoneda, M | 1 |
| Bonnar, J | 1 |
| DOWD, JE | 1 |
| DIPAOLO, JA | 1 |
| WATNE, AL | 1 |
| CAVANAGH, D | 2 |
| MARTIN, DS | 2 |
| FERGUSON, JH | 1 |
| HERNANDEZ-ROMAN, P | 1 |
| Ishihara, S | 1 |
| Kumada, S | 1 |
| Takai, K | 1 |
| Iwata, M | 1 |
| Nakamura, T | 1 |
| Kawase, S | 1 |
| Suzuki, K | 1 |
| Mori, Y | 1 |
| Satoh, C | 1 |
| Fukushima, H | 1 |
| Ota, T | 1 |
| Yanagawa, S | 1 |
| Sugarbaker, PH | 1 |
| Stuart, OA | 1 |
| Yoo, D | 1 |
| Kumar, AA | 1 |
| Sadoul, G | 1 |
| Beuret, T | 1 |
| Sillman, FH | 3 |
| Boyce, JG | 2 |
| Macasaet, MA | 1 |
| Nicastri, AD | 1 |
| Klutke, JJ | 1 |
| Bergman, A | 1 |
| Grigsby, PW | 2 |
| Graham, MV | 1 |
| Perez, CA | 2 |
| Galakatos, AE | 2 |
| Camel, HM | 2 |
| Kao, MS | 2 |
| Gutman, M | 1 |
| Abu-Abid, S | 1 |
| Sorkine, P | 1 |
| Inbar, M | 1 |
| Lev, D | 1 |
| Chen, Z | 1 |
| Oron, D | 1 |
| Chaitchik, S | 1 |
| Klausner, JM | 1 |
| Zeyi, C | 1 |
| Zongbing, Y | 1 |
| Shiying, Z | 1 |
| Zhilan, P | 1 |
| Jinghua, W | 1 |
| Peiyi, L | 1 |
| Fishman, A | 1 |
| Chowers, M | 1 |
| Altaras, M | 1 |
| Beyth, Y | 1 |
| Lang, R | 1 |
| Shimizu, Y | 2 |
| Marzotko, F | 3 |
| Krafft, W | 3 |
| Preibsch, W | 2 |
| Schröder, M | 1 |
| Slack, NH | 1 |
| Bross, ID | 1 |
| Krebs, HB | 4 |
| Kersh, CR | 1 |
| Constable, WC | 1 |
| Spaulding, CA | 1 |
| Hahn, SS | 1 |
| Andersen, WA | 1 |
| Taylor, PT | 1 |
| Thivolet, J | 2 |
| Pride, GL | 1 |
| Silva, PD | 1 |
| Micha, JP | 1 |
| Silva, DG | 1 |
| Thomas, L | 1 |
| Dozono, H | 1 |
| Nakamura, K | 1 |
| Motoya, T | 1 |
| Nakamura, S | 1 |
| Shinmura, R | 1 |
| Miwa, K | 1 |
| Ishibashi, M | 1 |
| Nagata, Y | 2 |
| Kuske, RR | 1 |
| Lovett, RD | 1 |
| Jacobs, AJ | 1 |
| Sedlis, A | 2 |
| Sakakibara, K | 1 |
| Mizuno, K | 1 |
| Kano, T | 1 |
| Ohta, M | 1 |
| Tomita, Y | 1 |
| Yoshio, G | 1 |
| Tokuhashi, Y | 1 |
| Nishida, Y | 1 |
| Okamoto, E | 1 |
| Hori, M | 1 |
| Schneider, V | 1 |
| Hurt, WG | 1 |
| Goplerud, DR | 1 |
| Ueda, T | 1 |
| Kamiwatari, M | 1 |
| Kosya, S | 1 |
| Yamamoto, S | 1 |
| Shiokawa, H | 1 |
| Yamada, E | 1 |
| Djawari, D | 1 |
| Schmidt, KU | 1 |
| Wiskemann, A | 1 |
| Mensing, H | 1 |
| Miura, S | 1 |
| Okudaira, Y | 1 |
| Kalra, J | 1 |
| Cortes, E | 1 |
| Chen, S | 1 |
| Krumholz, B | 1 |
| Rovinsky, JJ | 1 |
| Molho, L | 1 |
| Seltzer, V | 1 |
| Papantoniou, P | 1 |
| Lee, JY | 1 |
| Fuller, AF | 1 |
| Krane, IM | 1 |
| Budzik, GP | 1 |
| Donahoe, PK | 1 |
| Stringel, G | 1 |
| Spence, J | 1 |
| Corsini, L | 1 |
| Smith, JP | 1 |
| Rutledge, F | 1 |
| Sutow, WW | 1 |
| Bloomfield, RD | 1 |
| Niedner, K | 1 |
| Malkasian, GD | 2 |
| Decker, DG | 2 |
| Jorgensen, EO | 1 |
| Webb, MJ | 1 |
| Preibsche, W | 1 |
| Lewis, GC | 1 |
| Wolff, JP | 1 |
| Mussey, E | 1 |
| Johnson, CE | 1 |
| Chakravorty, RC | 1 |
| Sarkar, SK | 1 |
| Mukerji, B | 1 |
| Lutziger, H | 1 |
| Berger, M | 1 |
| Persianinov, LS | 1 |
| Gasparian, NN | 1 |
| Gasparian, SA | 1 |
8 reviews available for fluorouracil and Genital Neoplasms, Female
| Article | Year |
|---|---|
Strategies for management of the peritoneal surface component of cancer: cytoreductive surgery plus perioperative intraperitoneal chemotherapy.
Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Combined Modality Therapy; Doxorubicin; Female; Fluor | 2005 |
[Recent advances in intraarterial chemotherapy in gynecologic malignancy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemoembolization, Therapeutic; Cisplatin | 2002 |
[Treatment of genital warts and condyloma].
Topics: Antiviral Agents; Bleomycin; Condylomata Acuminata; Cryosurgery; Dinitrofluorobenzene; Electrocoagul | 1988 |
Phase I/II study of definitive radiotherapy and chemotherapy (cisplatin and 5-fluorouracil) for advanced or recurrent gynecologic malignancies. Preliminary report.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; C | 1989 |
Anogenital papillomavirus infection and neoplasia in immunodeficient women.
Topics: Acquired Immunodeficiency Syndrome; Combined Modality Therapy; Female; Fluorouracil; Genital Neoplas | 1987 |
A review of lower genital intraepithelial neoplasia and the use of topical 5-fluorouracil.
Topics: Acquired Immunodeficiency Syndrome; Administration, Topical; Adult; Anal Canal; Anus Neoplasms; Carc | 1985 |
The use of topical 5-fluorouracil in the treatment of genital condylomas.
Topics: Administration, Topical; Combined Modality Therapy; Condylomata Acuminata; Female; Fluorouracil; Gen | 1987 |
Current cancer chemotherapy in obstetrics and gynecology.
Topics: Alkaloids; Alkylating Agents; Anti-Bacterial Agents; Antimetabolites; Blood Cell Count; Bone Marrow; | 1971 |
7 trials available for fluorouracil and Genital Neoplasms, Female
| Article | Year |
|---|---|
Interferon as an adjuvant treatment for genital condyloma acuminatum.
Topics: Adolescent; Adult; Combined Modality Therapy; Condylomata Acuminata; Female; Fluorouracil; Genital N | 1995 |
Prospective phase I/II studies of definitive irradiation and chemotherapy for advanced gynecologic malignancies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Cisplatin; Combined Modality Therapy; | 1996 |
Regional perfusion with hemofiltration (chemofiltration) for the treatment of patients with regionally advanced cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma | 1996 |
Chemotherapy for lymphatic metastatic gynecologic cancer via pelvic retroperitoneal cannulation: a preliminary report.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Catheterization, Peripheral; Feasibility Studies; Fema | 1996 |
Management of condyloma acuminatum.
Topics: Clinical Trials as Topic; Condylomata Acuminata; Cryosurgery; Electrocoagulation; Female; Fluorourac | 1985 |
[Prevention of stomatitis induced by anti-cancer drugs].
Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophospham | 1989 |
Evaluation of 6,17 alpha-dimethyl-6-dehydroprogesterone for treatment of recurrent and metastatic gynecologic malignancy.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Clinical Trials as Topic; Cyclophosphamide; Drug | 1974 |
40 other studies available for fluorouracil and Genital Neoplasms, Female
| Article | Year |
|---|---|
Impact of chemotherapy on normal tissue complication probability models of acute hematologic toxicity in patients receiving pelvic intensity modulated radiation therapy.
Topics: Aged; Antineoplastic Agents; Anus Neoplasms; Bone Marrow; Chemoradiotherapy; Cisplatin; Drug Adminis | 2013 |
Retrospective case series of 15 patients treated with chemoradiation using 5-FU and nedaplatin for gynecological malignancy: with regard to hemotoxicity.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chemoradiotherapy; Female; | 2014 |
[Comments on "Normal tissue tolerance to external beam radiotherapy: Small bowel" by Martin et al. (Cancer Radiother 14:350-3)].
Topics: Antineoplastic Agents; Combined Modality Therapy; Female; Fluorouracil; Genital Neoplasms, Female; H | 2011 |
Ulcerated plaques in the pelvic region of an adult female.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Capecitabine; Carcinoma, D | 2012 |
The MTS assay as an indicator of chemosensitivity/resistance in malignant gynaecological tumours.
Topics: Antineoplastic Agents; Cell Survival; Cells, Cultured; Cisplatin; Drug Resistance, Neoplasm; Drug Sc | 2003 |
INDIVIDUALIZED CHEMOTHERAPY BY IN VITRO DRUG SELECTION.
Topics: Antineoplastic Agents; Bone Neoplasms; Dactinomycin; Female; Floxuridine; Fluorouracil; Genital Neop | 1964 |
CLOSED PELVIC PERFUSION IN ADVANCED GYNECOLOGIC CANCER.
Topics: Catheterization; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Fluorouracil; F | 1965 |
CLOSED PELVIC PERFUSION: A NEW APPROACH TO THE PROBLEM OF ADVANCED GYNECOLOGIC MALIGNANCY.
Topics: Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Drug Therapy; Female; Fluorouracil; Geni | 1965 |
[Chemoradiation using 5-fluorouracil (5-FU) and nedaplatin (NDP) for gynecological malignancy--the relation between hemotoxicity and sequence of 5-FU and NDP].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Adminis | 2004 |
Topical 5-FU helpful in reducing the rate of recurrence of condylomata acuminata.
Topics: Condylomata Acuminata; Female; Fluorouracil; Genital Neoplasms, Female; Genital Neoplasms, Male; Hum | 1982 |
[Treatment of genital condyloma using CO2 laser and topical application of fluorouracil].
Topics: Administration, Topical; Adult; Condylomata Acuminata; Female; Fluorouracil; Genital Neoplasms, Fema | 1982 |
5-fluorouracil/chemosurgery for intraepithelial neoplasia of the lower genital tract.
Topics: Adult; Aged; Carcinoma in Situ; Female; Fluorouracil; Genital Neoplasms, Female; Humans; Methods; Mi | 1981 |
Aztreonam plus piperacillin--empiric treatment of neutropenic fever in gynecology-oncology patients receiving cisplatin-based chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Aztreonam; Bacterial | 1998 |
[In vitro testing and clinical experience with 5-fluorouracil in gynaecologic cancer (author's transl)].
Topics: Adult; Aged; Culture Techniques; Drug Evaluation; Female; Fluorouracil; Genital Neoplasms, Female; H | 1976 |
The influence of site of metastasis on tumour growth and response to chemotherapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Female; Fluorouracil; Genital Neoplasms, Fema | 1975 |
Treatment of genital condylomata with topical 5-fluorouracil.
Topics: Administration, Topical; Anus Neoplasms; Combined Modality Therapy; Condylomata Acuminata; Female; F | 1991 |
A phase I-II trial of multimodality management of bulky gynecologic malignancy. Combined chemoradiosensitization and radiotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol | 1990 |
[Treatment of condylomata acuminata].
Topics: Condylomata Acuminata; Female; Fluorouracil; Genital Neoplasms, Female; Genital Neoplasms, Male; Hum | 1990 |
Treatment of large lower genital tract condylomata acuminata with topical 5-fluorouracil.
Topics: Administration, Topical; Adolescent; Adult; Condylomata Acuminata; Female; Fluorouracil; Genital Neo | 1990 |
[The determination of thymidylate synthetase inhibition for testing fluoropyrimidines--pharmacokinetics and metabolism of carmofur (HCFU) in patients with gynecologic malignancies--Tokai HCFU Study Group for Gynecologic Malignancies].
Topics: Antineoplastic Agents; Female; Floxuridine; Fluorouracil; Genital Neoplasms, Female; Half-Life; Huma | 1986 |
Genital condylomas in immunosuppressed women: a therapeutic challenge.
Topics: Adult; Antineoplastic Agents; Combined Modality Therapy; Condylomata Acuminata; Female; Fluorouracil | 1986 |
[A study on UFT concentration in tissues and serum of patients with malignant gynecologic tumors following oral administration].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Genital | 1987 |
Combination of laser plus 5-fluorouracil for the treatment of extensive genital condylomata acuminata.
Topics: Combined Modality Therapy; Condylomata Acuminata; Female; Fluorouracil; Genital Neoplasms, Female; H | 1988 |
Interferon for treatment of genital warts.
Topics: Condylomata Acuminata; Cryosurgery; Electrocoagulation; Female; Fluorouracil; Genital Neoplasms, Fem | 1988 |
[5-Fluorouracil treatment of condylomata acuminata].
Topics: Administration, Topical; Adult; Condylomata Acuminata; Female; Fluorouracil; Genital Neoplasms, Fema | 1986 |
[Etretinate and 5-fluorouracil in intra-anal Bowen's disease].
Topics: Adult; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bowen's Disease; | 1986 |
[Consecutive intra-arterial infusion of cis-diamminedichloroplatinum with continuous intra-arterial infusion of 5-fluorouracil in patients with advanced gynecologic cancer].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorour | 1986 |
Effective multimodality treatment for advanced epidermoid carcinoma of the female genital tract.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, | 1985 |
Mullerian inhibiting substance reduction of colony growth of human gynecologic cancers in a stem cell assay.
Topics: Adenocarcinoma; Altretamine; Anti-Mullerian Hormone; Ascitic Fluid; Carcinoma; Chromatography, Affin | 1985 |
Genital warts in children.
Topics: Adolescent; Child; Child, Preschool; Condylomata Acuminata; Electrocoagulation; Female; Fluorouracil | 1985 |
Malignant gynecologic tumors in children: current approaches to treatment.
Topics: Age Factors; Child; Child, Preschool; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Dysgerminoma; | 1973 |
[Registration of cytostatic effects in vitro by means of an objective method of cell counting (ZZV) (author's transl)].
Topics: Antineoplastic Agents; Cell Count; Culture Techniques; Cyclophosphamide; Female; Fluorouracil; Genit | 1974 |
[Experiences on in vitro testing of cytostatic sensitivity (oncobiogram) in gynecological tumors].
Topics: Antineoplastic Agents; Cyclophosphamide; Drug Resistance; Female; Fluorouracil; Genital Neoplasms, F | 1973 |
Gynecologic oncology.
Topics: Alkylating Agents; Ascites; Biopsy; Dactinomycin; Endometrium; Female; Fluorouracil; Genital Neoplas | 1973 |
[Antineoplastic chemotherapy in gynecology; some generalizations].
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Cyclophospha | 1967 |
[Chemotherapy in the gynecologic oncology].
Topics: Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Fluoroura | 1971 |
Observations on gynecologic malignancy treated with 5-fluorouracil.
Topics: Adult; Age Factors; Aged; Fallopian Tube Neoplasms; Female; Fluorouracil; Genital Neoplasms, Female; | 1968 |
The use of parenteral 5-fluorouracil in solid tumours. A preliminary report.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Female; Fluorouracil; Gastrointestinal Neoplasms; Genital | 1969 |
[On 5-fluorouracil treatment of advanced gynecologic carcinomas].
Topics: Adult; Aged; Breast Neoplasms; Female; Fluorouracil; Genital Neoplasms, Female; Humans; Middle Aged | 1966 |
[On methods of prolonged intra-arterial chemotherapy of malignant neoplasms of the genitalia].
Topics: Adult; Aorta, Abdominal; Female; Fluorouracil; Genital Neoplasms, Female; Humans; Iliac Artery; Infu | 1966 |