Page last updated: 2024-10-27

fluorouracil and Genital Diseases, Male

fluorouracil has been researched along with Genital Diseases, Male in 12 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Genital Diseases, Male: Pathological processes involving the male reproductive tract (GENITALIA, MALE).

Research Excerpts

ExcerptRelevanceReference
"A new intralesional sustained-release chemotherapy is under development as a treatment for condylomata acuminata; it is administered as an injectable gel that consists of fluorouracil and epinephrine with a purified bovine collagen as the gellant (fluorouracil/epinephrine gel)."9.08Intralesional fluorouracil/epinephrine injectable gel for treatment of condylomata acuminata. A phase 3 clinical study. ( Gordon, S; Korey, A; Kraus, S; McCarty, JM; Orenberg, EK; Phillips, S; Skinner, R; Sperling, M; Swinehart, JM; Webster, GF, 1997)
"A new intralesional sustained-release chemotherapy is under development as a treatment for condylomata acuminata; it is administered as an injectable gel that consists of fluorouracil and epinephrine with a purified bovine collagen as the gellant (fluorouracil/epinephrine gel)."5.08Intralesional fluorouracil/epinephrine injectable gel for treatment of condylomata acuminata. A phase 3 clinical study. ( Gordon, S; Korey, A; Kraus, S; McCarty, JM; Orenberg, EK; Phillips, S; Skinner, R; Sperling, M; Swinehart, JM; Webster, GF, 1997)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's2 (16.67)18.2507
2000's2 (16.67)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sellick, MJ1
Michaud, M1
Wong, S1
Candler, D1
Watanabe, SM1
Imran, F1
Harman, K1
Schiffman, LA1
Berry, R1
Watsky, M1
Heilman, E1
Fleta-Asín, B1
Alcántara-González, J1
Alonso-Castro, L1
Truchuelo-Díez, M1
Jaén-Olasolo, P1
Pall, A1
Mahajan, BB1
Puri, KP1
Gupta, RR1
Oriel, JD1
Relakis, K1
Cardamakis, E1
Korantzis, A1
Metalinos, K1
Mantouvalos, H1
Papathanasiou, Z1
Michopoulos, J1
Stathopoulos, E1
Kotoulas, IG1
Tzingounis, V1
Swinehart, JM1
Sperling, M1
Phillips, S1
Kraus, S1
Gordon, S1
McCarty, JM1
Webster, GF1
Skinner, R1
Korey, A1
Orenberg, EK1
Thomas, L1
Thivolet, J1
Rosemberg, SK1
Krebs, HB1
Shelley, WB1
Shelley, ED1

Reviews

1 review available for fluorouracil and Genital Diseases, Male

ArticleYear
[Treatment of genital warts and condyloma].
    Annales de dermatologie et de venereologie, 1988, Volume: 115, Issue:2

    Topics: Antiviral Agents; Bleomycin; Condylomata Acuminata; Cryosurgery; Dinitrofluorobenzene; Electrocoagul

1988

Trials

3 trials available for fluorouracil and Genital Diseases, Male

ArticleYear
Therapeutic evaluation of intralesional 5% 5-fluorouracil in condyloma acuminata.
    The Journal of dermatology, 2004, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Condylomata Acuminata; Female; Fluorouraci

2004
Treatment of men with flat (FC) or acuminata (CA) condylomata with interferon alpha-2a.
    European journal of gynaecological oncology, 1996, Volume: 17, Issue:6

    Topics: Administration, Topical; Adult; Analysis of Variance; Antimetabolites, Antineoplastic; Antiviral Age

1996
Intralesional fluorouracil/epinephrine injectable gel for treatment of condylomata acuminata. A phase 3 clinical study.
    Archives of dermatology, 1997, Volume: 133, Issue:1

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Condylomata Acuminata; Double-Blind Method

1997

Other Studies

8 other studies available for fluorouracil and Genital Diseases, Male

ArticleYear
Subcutaneous Draining of Lower Extremity Edema in a Patient With Advanced Cancer Relieves Scrotal Swelling and Improves Mobility.
    Journal of oncology practice, 2018, Volume: 14, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drainage; Edema; Fluoroura

2018
A perplexing case.
    Clinical and experimental dermatology, 2016, Volume: 41, Issue:5

    Topics: Aged, 80 and over; Drug Eruptions; Fluorouracil; Genital Diseases, Male; Groin; Humans; Male; Skin U

2016
Annular patches and plaques on the scrotum and buttocks. Genital porokeratosis.
    Archives of dermatology, 2009, Volume: 145, Issue:6

    Topics: Administration, Topical; Biopsy, Needle; Black or African American; Buttocks; Fluorouracil; Genital

2009
Genital erythrodysesthesia as a severe manifestation of capecitabine therapy: a report of 3 cases.
    Archives of dermatology, 2011, Volume: 147, Issue:9

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Erythema; Flu

2011
Genital warts-recent advances.
    Clinical and experimental dermatology, 1982, Volume: 7, Issue:4

    Topics: Female; Fluorouracil; Genital Diseases, Female; Genital Diseases, Male; Humans; Male; Podophyllin; W

1982
Sexually transmitted papillomaviral infections: III. Management of male partner.
    Urology, 1988, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Combined Modality Therapy; Electrocoagulation; Female; Fluorouracil; Follow-Up St

1988
Management of human papillomavirus-associated genital lesions in men.
    Obstetrics and gynecology, 1989, Volume: 73, Issue:3 Pt 1

    Topics: Adolescent; Adult; Combined Modality Therapy; Condylomata Acuminata; Cryosurgery; Fluorouracil; Geni

1989
Scrotal dermatitis caused by 5-fluorouracil (Efudex).
    Journal of the American Academy of Dermatology, 1988, Volume: 19, Issue:5 Pt 2

    Topics: Adolescent; Adult; Condylomata Acuminata; Dermatitis, Contact; Drug Eruptions; Fluorouracil; Genital

1988