fluorouracil has been researched along with Genital Diseases, Male in 12 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Genital Diseases, Male: Pathological processes involving the male reproductive tract (GENITALIA, MALE).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A new intralesional sustained-release chemotherapy is under development as a treatment for condylomata acuminata; it is administered as an injectable gel that consists of fluorouracil and epinephrine with a purified bovine collagen as the gellant (fluorouracil/epinephrine gel)." | 9.08 | Intralesional fluorouracil/epinephrine injectable gel for treatment of condylomata acuminata. A phase 3 clinical study. ( Gordon, S; Korey, A; Kraus, S; McCarty, JM; Orenberg, EK; Phillips, S; Skinner, R; Sperling, M; Swinehart, JM; Webster, GF, 1997) |
| "A new intralesional sustained-release chemotherapy is under development as a treatment for condylomata acuminata; it is administered as an injectable gel that consists of fluorouracil and epinephrine with a purified bovine collagen as the gellant (fluorouracil/epinephrine gel)." | 5.08 | Intralesional fluorouracil/epinephrine injectable gel for treatment of condylomata acuminata. A phase 3 clinical study. ( Gordon, S; Korey, A; Kraus, S; McCarty, JM; Orenberg, EK; Phillips, S; Skinner, R; Sperling, M; Swinehart, JM; Webster, GF, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sellick, MJ | 1 |
| Michaud, M | 1 |
| Wong, S | 1 |
| Candler, D | 1 |
| Watanabe, SM | 1 |
| Imran, F | 1 |
| Harman, K | 1 |
| Schiffman, LA | 1 |
| Berry, R | 1 |
| Watsky, M | 1 |
| Heilman, E | 1 |
| Fleta-Asín, B | 1 |
| Alcántara-González, J | 1 |
| Alonso-Castro, L | 1 |
| Truchuelo-Díez, M | 1 |
| Jaén-Olasolo, P | 1 |
| Pall, A | 1 |
| Mahajan, BB | 1 |
| Puri, KP | 1 |
| Gupta, RR | 1 |
| Oriel, JD | 1 |
| Relakis, K | 1 |
| Cardamakis, E | 1 |
| Korantzis, A | 1 |
| Metalinos, K | 1 |
| Mantouvalos, H | 1 |
| Papathanasiou, Z | 1 |
| Michopoulos, J | 1 |
| Stathopoulos, E | 1 |
| Kotoulas, IG | 1 |
| Tzingounis, V | 1 |
| Swinehart, JM | 1 |
| Sperling, M | 1 |
| Phillips, S | 1 |
| Kraus, S | 1 |
| Gordon, S | 1 |
| McCarty, JM | 1 |
| Webster, GF | 1 |
| Skinner, R | 1 |
| Korey, A | 1 |
| Orenberg, EK | 1 |
| Thomas, L | 1 |
| Thivolet, J | 1 |
| Rosemberg, SK | 1 |
| Krebs, HB | 1 |
| Shelley, WB | 1 |
| Shelley, ED | 1 |
1 review available for fluorouracil and Genital Diseases, Male
| Article | Year |
|---|---|
[Treatment of genital warts and condyloma].
Topics: Antiviral Agents; Bleomycin; Condylomata Acuminata; Cryosurgery; Dinitrofluorobenzene; Electrocoagul | 1988 |
3 trials available for fluorouracil and Genital Diseases, Male
| Article | Year |
|---|---|
Therapeutic evaluation of intralesional 5% 5-fluorouracil in condyloma acuminata.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Condylomata Acuminata; Female; Fluorouraci | 2004 |
Treatment of men with flat (FC) or acuminata (CA) condylomata with interferon alpha-2a.
Topics: Administration, Topical; Adult; Analysis of Variance; Antimetabolites, Antineoplastic; Antiviral Age | 1996 |
Intralesional fluorouracil/epinephrine injectable gel for treatment of condylomata acuminata. A phase 3 clinical study.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Condylomata Acuminata; Double-Blind Method | 1997 |
8 other studies available for fluorouracil and Genital Diseases, Male
| Article | Year |
|---|---|
Subcutaneous Draining of Lower Extremity Edema in a Patient With Advanced Cancer Relieves Scrotal Swelling and Improves Mobility.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drainage; Edema; Fluoroura | 2018 |
A perplexing case.
Topics: Aged, 80 and over; Drug Eruptions; Fluorouracil; Genital Diseases, Male; Groin; Humans; Male; Skin U | 2016 |
Annular patches and plaques on the scrotum and buttocks. Genital porokeratosis.
Topics: Administration, Topical; Biopsy, Needle; Black or African American; Buttocks; Fluorouracil; Genital | 2009 |
Genital erythrodysesthesia as a severe manifestation of capecitabine therapy: a report of 3 cases.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Erythema; Flu | 2011 |
Genital warts-recent advances.
Topics: Female; Fluorouracil; Genital Diseases, Female; Genital Diseases, Male; Humans; Male; Podophyllin; W | 1982 |
Sexually transmitted papillomaviral infections: III. Management of male partner.
Topics: Adolescent; Adult; Combined Modality Therapy; Electrocoagulation; Female; Fluorouracil; Follow-Up St | 1988 |
Management of human papillomavirus-associated genital lesions in men.
Topics: Adolescent; Adult; Combined Modality Therapy; Condylomata Acuminata; Cryosurgery; Fluorouracil; Geni | 1989 |
Scrotal dermatitis caused by 5-fluorouracil (Efudex).
Topics: Adolescent; Adult; Condylomata Acuminata; Dermatitis, Contact; Drug Eruptions; Fluorouracil; Genital | 1988 |