fluorouracil has been researched along with Gastroduodenal Ulcer in 8 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The prognosis of patients with hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) is extremely poor." | 2.70 | Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombosis: analysis of 48 cases. ( Ando, E; Fukumori, K; Kuromatsu, R; Okuda, K; Sata, M; Sumie, S; Tanaka, M; Yamashita, F; Yano, Y; Yutani, S, 2002) |
| "Omeprazole was significantly more effective than placebo and misoprostol in reducing the frequency and degree of the endoscopic worsening, either after CMF or after 5-FU (P < 0." | 2.68 | Misoprostol and omeprazole in the prevention of chemotherapy-induced acute gastroduodenal mucosal injury. A randomized, placebo-controlled pilot study. ( Abbasciano, V; Nielsen, I; Sartori, S; Tassinari, D; Trevisani, L, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ando, E | 1 |
| Tanaka, M | 1 |
| Yamashita, F | 1 |
| Kuromatsu, R | 1 |
| Yutani, S | 1 |
| Fukumori, K | 1 |
| Sumie, S | 1 |
| Yano, Y | 1 |
| Okuda, K | 1 |
| Sata, M | 1 |
| ROTH, JL | 1 |
| Maruyama, S | 1 |
| Bright-Asare, P | 1 |
| Whiten, JT | 1 |
| Sartori, S | 1 |
| Trevisani, L | 1 |
| Nielsen, I | 1 |
| Tassinari, D | 1 |
| Abbasciano, V | 1 |
| Takao, T | 1 |
| Nishida, M | 1 |
| Maeda, Y | 1 |
| Takao, K | 1 |
| Oka, M | 1 |
| Jewell, LD | 1 |
| Fields, AL | 1 |
| Murray, CJ | 1 |
| Thomson, AB | 1 |
| Lapsa, RKh | 1 |
1 review available for fluorouracil and Gastroduodenal Ulcer
| Article | Year |
|---|---|
[Complications of hepatic artery chemotherapy for liver metastases in colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Cholangitis, Sclerosing | 2003 |
2 trials available for fluorouracil and Gastroduodenal Ulcer
| Article | Year |
|---|---|
Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombosis: analysis of 48 cases.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Female; | 2002 |
Misoprostol and omeprazole in the prevention of chemotherapy-induced acute gastroduodenal mucosal injury. A randomized, placebo-controlled pilot study.
Topics: Adult; Aged; Anti-Ulcer Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; F | 1996 |
5 other studies available for fluorouracil and Gastroduodenal Ulcer
| Article | Year |
|---|---|
ROLE OF DRUGS IN PRODUCTION OF GASTRODUODENAL ULCER.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aspirin; Caffeine; Cats; Fluorouracil; Histami | 1964 |
Prostaglandins, gastroduodenal ulcer and hemorrhagic gastritis.
Topics: Animals; Cimetidine; Dogs; Double-Blind Method; Female; Fluorouracil; Gastritis; Gastrointestinal He | 1984 |
[The study of continuous infusion chemotherapy with low-dose cisplatin and 5-fluorouracil for patients with primary liver cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cholangiocarcinoma; | 1997 |
Erosive gastroduodenitis with marked epithelial atypia after hepatic arterial infusion chemotherapy.
Topics: Adenocarcinoma; Aluminum; Cimetidine; Colonic Neoplasms; Fluorouracil; Gastric Mucosa; Humans; Infus | 1985 |
[The reactivity of the RES in cancer of the gastrointestinal tract and during treatment with fluorofur].
Topics: Achlorhydria; Adult; Aged; Colonic Neoplasms; Esophageal Neoplasms; Female; Fluorouracil; Furans; Go | 1972 |