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fluorouracil and Gastritis

fluorouracil has been researched along with Gastritis in 10 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Gastritis: Inflammation of the GASTRIC MUCOSA, a lesion observed in a number of unrelated disorders.

Research Excerpts

ExcerptRelevanceReference
"We believe this case to be the second case of radiation recall presenting as diffuse gastritis in a patient receiving capecitabine after previous treatment with XRT."3.73Radiation recall phenomenon secondary to capecitabine: possible role of thymidine phosphorylase. ( Black, G; Diasio, R; Johnson, M; Russo, S; Saif, MW, 2006)
"Renal cell carcinoma is a common neoplasm that is often refractory to treatment."2.68A phase II trial of interferon-alpha and 5-fluorouracil in patients with advanced renal cell carcinoma. A Southwest Oncology Group study. ( Blumenstein, BA; Crawford, ED; Elias, L; Flanigan, RC; Goodwin, JW; Kish, J; Lowe, BA; Wade, JL, 1996)
"We report a patient with pancreatic cancer who developed gastrointestinal bleeding secondary to radiation recall gastritis related to erlotinib exposure."1.40Radiation recall gastritis secondary to erlotinib in a patient with pancreatic cancer. ( Graziani, C; Hegde, S; Saif, MW, 2014)
"A 59-year-old woman with advanced gastric cancer was treated with continuous 5-fluorouracil infusion for thirty-five days."1.29Continuous 5-fluorouracil infusion causing acute gastric mucosal lesions. ( Kano, Y; Sasagawa, M; Seki, T; Suda, K, 1993)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's3 (30.00)18.2507
2000's2 (20.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Graziani, C1
Hegde, S1
Saif, MW2
Chon, YE1
Seong, J1
Kim, BK1
Cha, J1
Kim, SU1
Park, JY1
Ahn, SH1
Han, KH1
Chon, CY1
Shin, SK1
Kim, DY1
SHERLOCK, P1
Harting, MT1
Blakely, ML1
Herzog, CE1
Lally, KP1
Ajani, JA1
Andrassy, RJ1
Black, G1
Johnson, M1
Russo, S1
Diasio, R1
Bright-Asare, P1
Whiten, JT1
Smith, FP1
Schein, PS1
Macdonald, JS1
Woolley, PV1
Ornitz, R1
Rogers, C1
Suda, K1
Seki, T1
Kano, Y1
Sasagawa, M1
Elias, L1
Blumenstein, BA1
Kish, J1
Flanigan, RC1
Wade, JL1
Lowe, BA1
Goodwin, JW1
Crawford, ED1
Yamashita, F1
Tanaka, M1
Fukumori, K1
Ando, E1
Yano, Y1
Kato, O1
Yamamoto, H1
Fukuda, H1
Kusaba, T1
Tanikawa, K1
Sata, M1

Trials

2 trials available for fluorouracil and Gastritis

ArticleYear
A phase II trial of interferon-alpha and 5-fluorouracil in patients with advanced renal cell carcinoma. A Southwest Oncology Group study.
    Cancer, 1996, Sep-01, Volume: 78, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Agranulocytosis; Anemia; Antineoplastic Combined Chemotherapy Protoc

1996
A crossover study of oral administration of UFT in chronic liver disease: comparison of continuous and intermittent schedules.
    Anti-cancer drugs, 1998, Volume: 9, Issue:5

    Topics: Administration, Oral; Aged; Area Under Curve; Carcinoma, Hepatocellular; Chronic Disease; Cross-Over

1998

Other Studies

8 other studies available for fluorouracil and Gastritis

ArticleYear
Radiation recall gastritis secondary to erlotinib in a patient with pancreatic cancer.
    Anticancer research, 2014, Volume: 34, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Capecitabine; Combined Modality The

2014
Gastroduodenal complications after concurrent chemoradiation therapy in patients with hepatocellular carcinoma: endoscopic findings and risk factors.
    International journal of radiation oncology, biology, physics, 2011, Dec-01, Volume: 81, Issue:5

    Topics: Adult; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Chemoradiotherapy; Duodenal Ulcer

2011
ACUTE GASTRITIS RESULTING FROM REGIONAL INFUSION OF AN ANTIMETABOLITE.
    Bulletin of gastrointestinal endoscopy, 1963, Volume: 9

    Topics: Adenocarcinoma; Angiography; Antimetabolites; Chemotherapy, Cancer, Regional Perfusion; Diagnosis, D

1963
Treatment issues in pediatric gastric adenocarcinoma.
    Journal of pediatric surgery, 2004, Volume: 39, Issue:8

    Topics: Anastomosis, Roux-en-Y; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Sig

2004
Radiation recall phenomenon secondary to capecitabine: possible role of thymidine phosphorylase.
    Cancer chemotherapy and pharmacology, 2006, Volume: 58, Issue:6

    Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Combined Modality Therapy; Deoxycytidine; Dihyd

2006
Prostaglandins, gastroduodenal ulcer and hemorrhagic gastritis.
    Clinical physiology and biochemistry, 1984, Volume: 2, Issue:2-3

    Topics: Animals; Cimetidine; Dogs; Double-Blind Method; Female; Fluorouracil; Gastritis; Gastrointestinal He

1984
Fast neutron irradiation for locally advanced pancreatic cancer.
    International journal of radiation oncology, biology, physics, 1981, Volume: 7, Issue:11

    Topics: Adenocarcinoma; Colitis; Cost-Benefit Analysis; Energy Transfer; Esophagitis; Evaluation Studies as

1981
Continuous 5-fluorouracil infusion causing acute gastric mucosal lesions.
    Endoscopy, 1993, Volume: 25, Issue:6

    Topics: Adenocarcinoma; Female; Fluorouracil; Gastritis; Humans; Infusions, Parenteral; Middle Aged; Stomach

1993