Page last updated: 2024-10-27

fluorouracil and Gastric Outlet Obstruction

fluorouracil has been researched along with Gastric Outlet Obstruction in 5 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Gastric Outlet Obstruction: The hindering of output from the STOMACH into the SMALL INTESTINE. This obstruction may be of mechanical or functional origin such as EDEMA from PEPTIC ULCER; NEOPLASMS; FOREIGN BODIES; or AGING.

Research Excerpts

ExcerptRelevanceReference
"Metastatic pancreatic cancer is one of the leading causes of cancer-related deaths in North America and Europe."2.41Metastatic pancreatic cancer. ( Kulke, MH, 2002)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Zhang, LY1
Ma, JJ1
Zang, L1
Hong, HJ1
Lu, AG1
He, ZR1
Jiang, TY1
Zhao, X1
Fingerhut, A1
Zheng, MH1
Sun, Y1
Xu, X1
Hu, J1
Xu, J1
Qian, Z1
Qian, X1
Zhang, Q1
Shao, Q1
Ye, Z1
Muto, O1
Sawada, T1
Kotanagi, K1
Sato, K1
Kichiraku, T1
Iwasaki, W1
Kikkawa, M1
Ouchi, S1
Kotanagi, H1
Park, JM1
Chi, KC1
Kulke, MH1

Reviews

1 review available for fluorouracil and Gastric Outlet Obstruction

ArticleYear
Metastatic pancreatic cancer.
    Current treatment options in oncology, 2002, Volume: 3, Issue:6

    Topics: Antineoplastic Agents; Autonomic Nerve Block; Celiac Plexus; Cholestasis; Clinical Trials as Topic;

2002

Other Studies

4 other studies available for fluorouracil and Gastric Outlet Obstruction

ArticleYear
Staged laparoscopic management of locally advanced gastric cancer with outlet obstruction.
    Journal of surgical oncology, 2021, Volume: 123 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Docetaxel; Female; Fluoroura

2021
[Efficacies of neoadjuvant chemotherapy plus nutritional support in advanced gastric cancer complicated with pylori obstruction].
    Zhonghua yi xue za zhi, 2014, Mar-04, Volume: 94, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Gastric Outlet Ob

2014
Modified administration schedule of docetaxel, cisplatin, and fluorouracil for advanced or recurrent gastric cancer with gastrointestinal stenosis.
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Female; Fluorouracil; Ga

2014
Unresectable gastric cancer with gastric outlet obstruction and distant metastasis responding to intraperitoneal and folfox chemotherapy after palliative laparoscopic gastrojejunostomy: report of a case.
    World journal of surgical oncology, 2010, Dec-20, Volume: 8

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluoroura

2010