fluorouracil has been researched along with Gastric Outlet Obstruction in 5 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Gastric Outlet Obstruction: The hindering of output from the STOMACH into the SMALL INTESTINE. This obstruction may be of mechanical or functional origin such as EDEMA from PEPTIC ULCER; NEOPLASMS; FOREIGN BODIES; or AGING.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metastatic pancreatic cancer is one of the leading causes of cancer-related deaths in North America and Europe." | 2.41 | Metastatic pancreatic cancer. ( Kulke, MH, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, LY | 1 |
| Ma, JJ | 1 |
| Zang, L | 1 |
| Hong, HJ | 1 |
| Lu, AG | 1 |
| He, ZR | 1 |
| Jiang, TY | 1 |
| Zhao, X | 1 |
| Fingerhut, A | 1 |
| Zheng, MH | 1 |
| Sun, Y | 1 |
| Xu, X | 1 |
| Hu, J | 1 |
| Xu, J | 1 |
| Qian, Z | 1 |
| Qian, X | 1 |
| Zhang, Q | 1 |
| Shao, Q | 1 |
| Ye, Z | 1 |
| Muto, O | 1 |
| Sawada, T | 1 |
| Kotanagi, K | 1 |
| Sato, K | 1 |
| Kichiraku, T | 1 |
| Iwasaki, W | 1 |
| Kikkawa, M | 1 |
| Ouchi, S | 1 |
| Kotanagi, H | 1 |
| Park, JM | 1 |
| Chi, KC | 1 |
| Kulke, MH | 1 |
1 review available for fluorouracil and Gastric Outlet Obstruction
| Article | Year |
|---|---|
Metastatic pancreatic cancer.
Topics: Antineoplastic Agents; Autonomic Nerve Block; Celiac Plexus; Cholestasis; Clinical Trials as Topic; | 2002 |
4 other studies available for fluorouracil and Gastric Outlet Obstruction
| Article | Year |
|---|---|
Staged laparoscopic management of locally advanced gastric cancer with outlet obstruction.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Docetaxel; Female; Fluoroura | 2021 |
[Efficacies of neoadjuvant chemotherapy plus nutritional support in advanced gastric cancer complicated with pylori obstruction].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Gastric Outlet Ob | 2014 |
Modified administration schedule of docetaxel, cisplatin, and fluorouracil for advanced or recurrent gastric cancer with gastrointestinal stenosis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Female; Fluorouracil; Ga | 2014 |
Unresectable gastric cancer with gastric outlet obstruction and distant metastasis responding to intraperitoneal and folfox chemotherapy after palliative laparoscopic gastrojejunostomy: report of a case.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluoroura | 2010 |