fluorouracil has been researched along with Gallstone Disease in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "All of the gallbladders had significant arteritis, with narrowing or occlusion of lumina or necrosis of vessel walls." | 1.27 | Chemical cholecystitis associated with hepatic arterial chemotherapy delivered by a permanently implanted pump. ( Dakhil, SR; Housholder, DF; Marymont, JV; Travers, H, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bourmèche, M | 1 |
| Ben Salah, H | 1 |
| Kallel, M | 1 |
| Beyrouti, MI | 1 |
| Makni, S | 1 |
| Boudawara, T | 1 |
| Frikha, M | 1 |
| Daoud, J | 1 |
| Marymont, JV | 1 |
| Dakhil, SR | 1 |
| Travers, H | 1 |
| Housholder, DF | 1 |
| Chevrel, B | 1 |
| Chevrel, JP | 1 |
| Pemberton, LB | 1 |
| Diffenbaugh, WF | 1 |
| Strohl, EL | 1 |
1 review available for fluorouracil and Gallstone Disease
| Article | Year |
|---|---|
[A long survival after the treatment of a squamous cell carcinoma of the gallbladder].
Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemoradiotherapy, Adjuvant; Cholecystect | 2013 |
3 other studies available for fluorouracil and Gallstone Disease
| Article | Year |
|---|---|
Chemical cholecystitis associated with hepatic arterial chemotherapy delivered by a permanently implanted pump.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Arteritis; Carcinoma, Hepatocellular; Cholecystitis; Ch | 1985 |
[Gallbladder cancer].
Topics: Adenocarcinoma; Adenoma; Carcinoma; Cholelithiasis; Fluorouracil; Gallbladder Neoplasms; Humans; Mel | 1971 |
The surgical significance of carcinoma of the gallbladder.
Topics: Appendicitis; Autopsy; Cholecystectomy; Cholecystitis; Cholelithiasis; Cholestasis; Diagnosis, Diffe | 1971 |