fluorouracil has been researched along with Fuchs' Endothelial Dystrophy in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Fuchs' Endothelial Dystrophy: Disorder caused by loss of endothelium of the central cornea. It is characterized by hyaline endothelial outgrowths on Descemet's membrane, epithelial blisters, reduced vision, and pain.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Le, VNH | 1 |
| Wabnig, F | 1 |
| Bachmann, B | 1 |
| Cursiefen, C | 1 |
| Wong, RK | 1 |
| Greene, DP | 1 |
| Shield, DR | 1 |
| Eberhart, CG | 1 |
| Huang, JJ | 1 |
| Shayegani, A | 1 |
2 other studies available for fluorouracil and Fuchs' Endothelial Dystrophy
| Article | Year |
|---|---|
Epithelial downgrowth after Descemet membrane endothelial keratoplasty.
Topics: Aged; Antimetabolites; Corneal Diseases; Descemet Stripping Endothelial Keratoplasty; Endothelium, C | 2021 |
5-Fluorouracil for epithelial downgrowth after Descemet stripping automated endothelial keratoplasty.
Topics: Aged; Antimetabolites; Corneal Diseases; Descemet Stripping Endothelial Keratoplasty; Female; Fluoro | 2013 |