Page last updated: 2024-10-27

fluorouracil and Freckle, Melanotic

fluorouracil has been researched along with Freckle, Melanotic in 3 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"Topical treatment of skin cancer may therefore be more appropriate in certain instances."2.66Topical treatments for skin cancer. ( Boyle, GM; Cullen, JK; Parsons, PG; Simmons, JL, 2020)
"Amelanotic lentigo maligna melanoma (ALMM) is an infrequent presentation of lentigo maligna melanoma, less than thirty cases having been reported to date."2.40Amelanotic lentigo maligna melanoma: report of a case and review of the literature. ( de Moragas, JM; Puig, L; Rocamora, V; Romaní, J, 1999)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Cullen, JK1
Simmons, JL1
Parsons, PG1
Boyle, GM1
Bogenrieder, T1
Weitzel, C1
Schölmerich, J1
Landthaler, M1
Stolz, W1
Rocamora, V1
Puig, L1
Romaní, J1
de Moragas, JM1

Reviews

2 reviews available for fluorouracil and Freckle, Melanotic

ArticleYear
Topical treatments for skin cancer.
    Advanced drug delivery reviews, 2020, 01-01, Volume: 153

    Topics: Administration, Cutaneous; Antineoplastic Agents; Carcinoma, Basal Cell; Clinical Trials as Topic; D

2020
Amelanotic lentigo maligna melanoma: report of a case and review of the literature.
    Cutis, 1999, Volume: 64, Issue:1

    Topics: Aged; Antineoplastic Agents; Combined Modality Therapy; Cryotherapy; Dicarboxylic Acids; Female; Flu

1999

Other Studies

1 other study available for fluorouracil and Freckle, Melanotic

ArticleYear
Eruptive multiple lentigo-maligna-like lesions in a patient undergoing chemotherapy with an oral 5-fluorouracil prodrug for metastasizing colorectal carcinoma: a lesson for the pathogenesis of malignant melanoma?
    Dermatology (Basel, Switzerland), 2002, Volume: 205, Issue:2

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma; Colorectal Neoplasms

2002