fluorouracil has been researched along with Freckle, Melanotic in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Topical treatment of skin cancer may therefore be more appropriate in certain instances." | 2.66 | Topical treatments for skin cancer. ( Boyle, GM; Cullen, JK; Parsons, PG; Simmons, JL, 2020) |
| "Amelanotic lentigo maligna melanoma (ALMM) is an infrequent presentation of lentigo maligna melanoma, less than thirty cases having been reported to date." | 2.40 | Amelanotic lentigo maligna melanoma: report of a case and review of the literature. ( de Moragas, JM; Puig, L; Rocamora, V; Romaní, J, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Cullen, JK | 1 |
| Simmons, JL | 1 |
| Parsons, PG | 1 |
| Boyle, GM | 1 |
| Bogenrieder, T | 1 |
| Weitzel, C | 1 |
| Schölmerich, J | 1 |
| Landthaler, M | 1 |
| Stolz, W | 1 |
| Rocamora, V | 1 |
| Puig, L | 1 |
| Romaní, J | 1 |
| de Moragas, JM | 1 |
2 reviews available for fluorouracil and Freckle, Melanotic
| Article | Year |
|---|---|
Topical treatments for skin cancer.
Topics: Administration, Cutaneous; Antineoplastic Agents; Carcinoma, Basal Cell; Clinical Trials as Topic; D | 2020 |
Amelanotic lentigo maligna melanoma: report of a case and review of the literature.
Topics: Aged; Antineoplastic Agents; Combined Modality Therapy; Cryotherapy; Dicarboxylic Acids; Female; Flu | 1999 |
1 other study available for fluorouracil and Freckle, Melanotic
| Article | Year |
|---|---|
Eruptive multiple lentigo-maligna-like lesions in a patient undergoing chemotherapy with an oral 5-fluorouracil prodrug for metastasizing colorectal carcinoma: a lesson for the pathogenesis of malignant melanoma?
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma; Colorectal Neoplasms | 2002 |