fluorouracil has been researched along with Foreign-Body Reaction in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Foreign-Body Reaction: Chronic inflammation and granuloma formation around irritating foreign bodies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-Fluorouracil (5-FU) was used as a model drug, and hydroxyapatite (HA) was incorporated as a release modifier." | 1.36 | In vitro / in vivo evaluation of NCDS-micro-fabricated biodegradable implant. ( Ahn, SH; Chi, SC; Danh, SD; Park, CW; Park, ES; Park, SH; Rhee, YS, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bowles, A | 1 |
| Ghalili, S | 1 |
| Ojong, OB | 1 |
| Vasile, GF | 1 |
| Li, YM | 1 |
| Aguilera, SB | 1 |
| Park, CW | 1 |
| Rhee, YS | 1 |
| Park, SH | 1 |
| Danh, SD | 1 |
| Ahn, SH | 1 |
| Chi, SC | 1 |
| Park, ES | 1 |
| Conejo-Mir, JS | 1 |
| Sanz Guirado, S | 1 |
| Angel Muñoz, M | 1 |
| Hasty, B | 1 |
| Heuer, DK | 1 |
| Minckler, DS | 1 |
4 other studies available for fluorouracil and Foreign-Body Reaction
| Article | Year |
|---|---|
Novel management of granuloma formation secondary to dermal filler: A multi-modality approach.
Topics: Cosmetic Techniques; Dermal Fillers; Fluorouracil; Foreign-Body Reaction; Granuloma, Foreign-Body; H | 2023 |
In vitro / in vivo evaluation of NCDS-micro-fabricated biodegradable implant.
Topics: Absorbable Implants; Animals; Antimetabolites, Antineoplastic; Chemistry, Pharmaceutical; Delayed-Ac | 2010 |
Adverse granulomatous reaction to Artecoll treated by intralesional 5-fluorouracil and triamcinolone injections.
Topics: Anti-Inflammatory Agents; Collagen; Face; Female; Fluorouracil; Foreign-Body Reaction; Glucocorticoi | 2006 |
Primate trabeculectomies with 5-fluorouracil collagen implants.
Topics: Animals; Anterior Chamber; Biological Dressings; Double-Blind Method; Drug Implants; Fibroblasts; Fl | 1990 |