fluorouracil has been researched along with Foot and Mouth Disease in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rai, DK | 1 |
| Diaz-San Segundo, F | 1 |
| Campagnola, G | 1 |
| Keith, A | 1 |
| Schafer, EA | 1 |
| Kloc, A | 1 |
| de Los Santos, T | 1 |
| Peersen, O | 1 |
| Rieder, E | 1 |
| Zeng, J | 2 |
| Wang, H | 2 |
| Xie, X | 2 |
| Yang, D | 2 |
| Zhou, G | 2 |
| Yu, L | 2 |
| Li, C | 1 |
3 other studies available for fluorouracil and Foot and Mouth Disease
| Article | Year |
|---|---|
Attenuation of Foot-and-Mouth Disease Virus by Engineered Viral Polymerase Fidelity.
Topics: Amino Acid Substitution; Animals; Antigens, Viral; Antiviral Agents; Cells, Cultured; Cricetinae; Di | 2017 |
An increased replication fidelity mutant of foot-and-mouth disease virus retains fitness in vitro and virulence in vivo.
Topics: Animals; Fluorouracil; Foot-and-Mouth Disease; Foot-and-Mouth Disease Virus; Humans; Mice; Mice, Inb | 2013 |
Foot-and-mouth disease virus low-fidelity polymerase mutants are attenuated.
Topics: Animals; Antiviral Agents; Base Sequence; Cell Line; Cricetinae; Drug Resistance, Viral; Fluorouraci | 2014 |