fluorouracil has been researched along with Foot Diseases in 7 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Foot Diseases: Anatomical and functional disorders affecting the foot.
| Excerpt | Relevance | Reference |
|---|---|---|
| "For almost 40 years, 5-fluorouracil (5-FU) has been the only useful drug with clinically meaningful activity in metastatic colorectal carcinoma." | 3.70 | Continuous infusion 5-fluorouracil as salvage chemotherapy in patients with advanced colorectal cancer. ( Au, E; Khoo, KS; Koo, WH; Lim, WT, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DIPAOLO, JA | 1 |
| Salk, RS | 1 |
| Grogan, KA | 1 |
| Chang, TJ | 1 |
| Lokich, JJ | 1 |
| Moore, C | 1 |
| Lim, WT | 1 |
| Koo, WH | 1 |
| Au, E | 1 |
| Khoo, KS | 1 |
| McCarthy, DJ | 2 |
| Tate, R | 1 |
| Rusin, J | 1 |
| Dockery, GL | 1 |
| Nilson, RZ | 1 |
1 trial available for fluorouracil and Foot Diseases
| Article | Year |
|---|---|
Topical 5% 5-fluorouracil cream in the treatment of plantar warts: a prospective, randomized, and controlled clinical study.
Topics: Administration, Topical; Adult; Aged; Analysis of Variance; Dose-Response Relationship, Drug; Drug A | 2006 |
6 other studies available for fluorouracil and Foot Diseases
| Article | Year |
|---|---|
POLYDACTYLISM IN THE OFFSPRING OF MICE INJECTED WITH 5-BROMODEOXYURIDINE.
Topics: Abnormalities, Drug-Induced; Animals; Blood Chemical Analysis; Bromodeoxyuridine; Family; Female; Fl | 1964 |
Chemotherapy-associated palmar-plantar erythrodysesthesia syndrome.
Topics: Antineoplastic Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; | 1984 |
Continuous infusion 5-fluorouracil as salvage chemotherapy in patients with advanced colorectal cancer.
Topics: Antimetabolites, Antineoplastic; Carcinoma; Catheterization, Central Venous; Cohort Studies; Colonic | 1999 |
Intradermal use of 5-fluorouracil in human pedal verrucae.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Fluorouracil; Foot Diseases; Humans; Male; Warts | 1979 |
Therapeutic considerations in the treatment of pedal verrucae.
Topics: Adrenal Cortex Hormones; Bleomycin; Caustics; Cryosurgery; Dinitrochlorobenzene; Electrosurgery; Flu | 1986 |
Intralesional injections.
Topics: Adrenal Cortex Hormones; Bleomycin; Fluorouracil; Foot Dermatoses; Foot Diseases; Humans; Hyaluronog | 1986 |