Page last updated: 2024-10-27

fluorouracil and Focal Nodular Hyperplasia

fluorouracil has been researched along with Focal Nodular Hyperplasia in 4 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Focal Nodular Hyperplasia: Solitary or multiple benign hepatic vascular tumors, usually occurring in women of 20-50 years of age. The nodule, poorly encapsulated, consists of a central stellate fibrous scar and normal liver elements such as HEPATOCYTES, small BILE DUCTS, and KUPFFER CELLS among the intervening fibrous septa. The pale colored central scar represents large blood vessels with hyperplastic fibromuscular layer and narrowing lumen.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Jain, C1
Syed, A1
Gupta, N1
Kambhoj, M1
Rao, A1
Singh, S1
Gutweiler, JR1
Yu, DC1
Kim, HB1
Kozakewich, HP1
Marcus, KJ1
Shamberger, RC1
Weldon, CB1
Wicherts, DA1
de Haas, RJ1
Sebagh, M1
Ciacio, O1
Lévi, F1
Paule, B1
Giacchetti, S1
Guettier, C1
Azoulay, D1
Castaing, D1
Adam, R1
Chen, CA1
Chen, M1

Reviews

1 review available for fluorouracil and Focal Nodular Hyperplasia

ArticleYear
Oxaliplatin-Induced Multiple Focal Nodular Hyperplasia Masquerading as Colorectal Liver Metastasis-Case Report and Review of Literature.
    Journal of gastrointestinal cancer, 2020, Volume: 51, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Digestive System S

2020

Other Studies

3 other studies available for fluorouracil and Focal Nodular Hyperplasia

ArticleYear
Hepatoblastoma presenting with focal nodular hyperplasia after treatment of neuroblastoma.
    Journal of pediatric surgery, 2008, Volume: 43, Issue:12

    Topics: Adrenal Gland Neoplasms; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplas

2008
Regenerative nodular hyperplasia of the liver related to chemotherapy: impact on outcome of liver surgery for colorectal metastases.
    Annals of surgical oncology, 2011, Volume: 18, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Com

2011
Simultaneous occurrence of hepatic focal nodular hyperplasia and uterine endometrial stromal nodule in a patient having treated breast infiltrating ductal carcinoma.
    Acta obstetricia et gynecologica Scandinavica, 2003, Volume: 82, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast;

2003