fluorouracil has been researched along with Focal Neurologic Deficits in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| NASH, DT | 1 |
| BRIN, M | 1 |
| HARROLD, MW | 1 |
| EDWARDS, CN | 1 |
| GRAVEY, FK | 1 |
| Pouillart, P | 1 |
| Schwarzenberg, L | 1 |
| Amiel, JL | 1 |
| Mathé, G | 1 |
| Huguenin, P | 1 |
| Morin, P | 1 |
| Baron, A | 1 |
| Laparre, Ch | 1 |
| Parrot, R | 1 |
| Weiss, HD | 1 |
| Walker, MD | 1 |
| Wiernik, PH | 1 |
1 review available for fluorouracil and Focal Neurologic Deficits
| Article | Year |
|---|---|
Neurotoxicity of commonly used antineoplastic agents (first of two parts).
Topics: Animals; Antineoplastic Agents; Asparaginase; Brain; Brain Diseases; Fluorouracil; Humans; Leukemia; | 1974 |
3 other studies available for fluorouracil and Focal Neurologic Deficits
| Article | Year |
|---|---|
MALABSORPTION IN MALIGNANT CARCINOID WITH NORMAL 5 HIAA.
Topics: Blood Chemical Analysis; Celiac Disease; Fluorouracil; Hydroxyindoleacetic Acid; Indoleacetic Acids; | 1964 |
TREATMENT OF BLADDER TUMORS BY DIRECT INSTILLATION OF 5-FLUOROURACIL. EXPERIMENTAL OBSERVATIONS IN DOGS.
Topics: Amines; Animals; Carcinogens; Carcinoma; Carcinoma, Transitional Cell; Dogs; Fluorouracil; Gastroent | 1964 |
[Chemotherapeutic combinations of mutually potentializing drugs. 1-Application to the treatment of breast cancers].
Topics: Aged; Alopecia; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Synergism; Drug Ther | 1975 |