Page last updated: 2024-10-27

fluorouracil and Fistula

fluorouracil has been researched along with Fistula in 11 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Fistula: Abnormal communication most commonly seen between two internal organs, or between an internal organ and the surface of the body.

Research Excerpts

ExcerptRelevanceReference
" Two patients with nasopharyngeal carcinoma complicated by collagen diseases (dermatomyositis in one, and Sjögren's syndrome with mixed connective tissue disease in the other) were given radiotherapy combined with chemotherapy consisting of cis-platinum and 5-fluorouracil."4.79Retropharyngeal abscess after radiation therapy and cis-platinum, 5-fluorouracil treatment for nasopharyngeal carcinoma with collagen disease: report of two patients and a review of the literature. ( Asakura, K; Hareyama, M; Hattori, A; Horikoshi, T; Hyodo, K; Imai, K; Koshiba, H; Morita, K; Nagakura, H; Oouchi, A; Sakata, K; Shido, M; Tamakawa, M; Tanaka, S, 1996)
"The effects of cisplatin and 5-fluorouracil on wound breaking strength and the rate of closure of an orocutaneous fistula were studied in 80 male rodents."3.68The effects of chemotherapy on murine wound healing and orocutaneous fistula closure. ( al-Sarraf, M; Grabow, D; Guan, ZX; Ledgerwood, AM; Lucas, CE; Weaver, A; Whittle, T, 1990)
"A total of 77 patients with cancer of the head and neck area were treated with five different drug combination regimens."1.26Combination chemotherapy of head and neck cancer. ( Byers, RM; Gard, DA; Goepfert, H; Guillamondegui, OM; Holoye, PY; Jesse, RH, 1978)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's4 (36.36)18.2507
2000's2 (18.18)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tello, CA1
Ahmed, II1
Khaw, PT1
Ohtsu, A1
Yoshida, S1
Boku, N1
Fujii, T1
Oda, Y1
Miyata, Y1
Koba, I1
Muro, K1
Ohnaka, O1
Shimizu, W1
Hareyama, M1
Nagakura, H1
Tamakawa, M1
Hyodo, K1
Asakura, K1
Horikoshi, T1
Tanaka, S1
Imai, K1
Hattori, A1
Oouchi, A1
Shido, M1
Koshiba, H1
Sakata, K1
Morita, K1
Sikma, MA1
Coenen, JL1
Kloosterziel, C1
Hasselt, BA1
Ruers, TJ1
Holoye, PY1
Byers, RM1
Gard, DA1
Goepfert, H1
Guillamondegui, OM1
Jesse, RH1
Copeland, EM1
Dudrick, SJ1
Gabrail, NY1
Harrison, BR1
Sunwoo, YC1
Whittle, T1
Lucas, CE1
Ledgerwood, AM1
Weaver, A1
al-Sarraf, M1
Guan, ZX1
Grabow, D1
Takasaki, H1
Uchida, Y1
Shigemitsu, O1
Oka, K1
Mori, Y1
Fujitomi, Y1
Ichimanda, M1
Shibata, O1
Shirabe, J1
Bissada, NK1
Redman, JF1
Sulieman, JS1
Waddell, WR1
Grover, FL1

Reviews

1 review available for fluorouracil and Fistula

ArticleYear
Retropharyngeal abscess after radiation therapy and cis-platinum, 5-fluorouracil treatment for nasopharyngeal carcinoma with collagen disease: report of two patients and a review of the literature.
    Japanese journal of clinical oncology, 1996, Volume: 26, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Collagen Diseas

1996

Other Studies

10 other studies available for fluorouracil and Fistula

ArticleYear
Failed trabeculectomy.
    Journal of glaucoma, 2005, Volume: 14, Issue:6

    Topics: Antimetabolites; Conjunctiva; Fistula; Fluorouracil; Glaucoma Drainage Implants; Glaucoma, Open-Angl

2005
Small cell carcinoma of the esophagus with an esophago-mediastinal fistula successfully treated by chemoradiation therapy and intubation: a case report.
    Japanese journal of clinical oncology, 1993, Volume: 23, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cobalt Radioisotop

1993
A breakthrough in cryosurgery.
    Surgical endoscopy, 2002, Volume: 16, Issue:5

    Topics: Antimetabolites, Antineoplastic; Bronchial Fistula; Carcinoma; Cryosurgery; Fistula; Fluorouracil; H

2002
Combination chemotherapy of head and neck cancer.
    Cancer, 1978, Volume: 42, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bleomycin; Bone Marrow; Carcinoma, Squamous Cell; Cy

1978
Cancer: nutritional concepts.
    Seminars in oncology, 1975, Volume: 2, Issue:4

    Topics: Acute Disease; Drug Tolerance; Fistula; Fluorouracil; Humans; Leukemia; Neoplasms; Nutrition Disorde

1975
Chemo-irradiation induced aortoesophageal fistula.
    Journal of surgical oncology, 1991, Volume: 48, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta, Thoracic; Aortic Diseases; Cisplatin; Combine

1991
The effects of chemotherapy on murine wound healing and orocutaneous fistula closure.
    The American surgeon, 1990, Volume: 56, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Fistula; Fluorouracil; Male; Mou

1990
[A case of abdominal wall fistula due to cholangioma].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:11

    Topics: Abdominal Muscles; Adenoma, Bile Duct; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neo

1985
Condyloma acuminatum of male urethra. Successful management with 5-fluorouracil.
    Urology, 1974, Volume: 3, Issue:4

    Topics: Adult; Condylomata Acuminata; Diverticulum; Fistula; Fluorouracil; Humans; Male; Neoplasm Recurrence

1974
The gallbladder as a conduit between the liver and intestine.
    Surgery, 1973, Volume: 74, Issue:4

    Topics: Adenocarcinoma; Adolescent; Adult; Bile Ducts; Carcinoma; Cholangiography; Common Bile Duct; Drainag

1973