fluorouracil has been researched along with Fasting Hypoglycemia in 8 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Fasting Hypoglycemia: HYPOGLYCEMIA expressed in the postabsorptive state, after prolonged FASTING, or an overnight fast.
| Excerpt | Relevance | Reference |
|---|---|---|
| "On treatment with PI103 or Ku-0063794, only the PIK3CA mutant cells displayed increased resistance in LG conditions." | 1.40 | Increased drug resistance is associated with reduced glucose levels and an enhanced glycolysis phenotype. ( Beloueche-Babari, M; Bhattacharya, B; Kamal Mustapa, N; Koh, KX; Loh, J; Low, SH; Soh, C; Soong, R, 2014) |
| "Hepatic hypoglycemia is discussed and the literature is reviewed." | 1.26 | Hypoglycemia secondary to metastases to the liver. A case report and review of the literature. ( Chawla, SK; LoPresti, PA; Sossi, AJ; Soterakis, J; Younus, S, 1977) |
| "Mice treated with ethionine (intraperitoneally, 5mg." | 1.25 | Stimulation of pentose phosphate pathway dehydrogenase enzyme activities in ethionine-treated mice. ( Fishman, WH; Sie, HG, 1968) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bhattacharya, B | 1 |
| Low, SH | 1 |
| Soh, C | 1 |
| Kamal Mustapa, N | 1 |
| Beloueche-Babari, M | 1 |
| Koh, KX | 1 |
| Loh, J | 1 |
| Soong, R | 1 |
| Yoshioka, M | 1 |
| Shibata, S | 1 |
| Uchinami, H | 1 |
| Watanabe, G | 1 |
| Miyazawa, H | 1 |
| Iida, M | 1 |
| Yoshida, M | 1 |
| Yoshioka, T | 1 |
| Nanjo, H | 1 |
| Yamamoto, Y | 1 |
| Hinchliffe, E | 1 |
| Allcock, RL | 1 |
| Mansoor, W | 1 |
| Myers, MA | 1 |
| Wright, J | 1 |
| Abolfathi, A | 1 |
| Penman, E | 1 |
| Marks, V | 1 |
| Cubilla, AL | 1 |
| Hajdu, SI | 1 |
| Younus, S | 1 |
| Soterakis, J | 1 |
| Sossi, AJ | 1 |
| Chawla, SK | 1 |
| LoPresti, PA | 1 |
| Patrassi, N | 1 |
| Basoli, A | 1 |
| Mineo, TC | 1 |
| Carboni, M | 1 |
| Sie, HG | 1 |
| Fishman, WH | 1 |
8 other studies available for fluorouracil and Fasting Hypoglycemia
| Article | Year |
|---|---|
Increased drug resistance is associated with reduced glucose levels and an enhanced glycolysis phenotype.
Topics: Antineoplastic Agents; Autophagy; Carboplatin; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kina | 2014 |
The transformation of a nonfunctioning islet cell tumor of the pancreas into a proinsulinoma under conditions of lung metastasis.
Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Is | 2015 |
A patient with a metastatic gastroenteropancreatic endocrine carcinoma causing hyperinsulinaemic hypoglycaemia and the carcinoid syndrome.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma; Fl | 2011 |
Pancreatic somatostatinoma presenting with hypoglycaemia.
Topics: Adenocarcinoma; Adult; Chlorothiazide; Diazoxide; Female; Fluorouracil; Humans; Hypoglycemia; Pancre | 1980 |
Islet cell carcinoma of the pancreas.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Child; Cyclophosphamide; Dactinomycin; Female; Fluorou | 1975 |
Hypoglycemia secondary to metastases to the liver. A case report and review of the literature.
Topics: Aged; Cyclophosphamide; Fluorouracil; Humans; Hypoglycemia; Liver Neoplasms; Male; Neoplasm Metastas | 1977 |
[Indications and medical therapy of hypoglycemic beta-insular].
Topics: Adenoma, Islet Cell; Adrenal Cortex Hormones; Antineoplastic Agents; Carcinoma; Diazoxide; Diuretics | 1973 |
Stimulation of pentose phosphate pathway dehydrogenase enzyme activities in ethionine-treated mice.
Topics: Adenosine Triphosphate; Animals; Antimetabolites; Blood Glucose; Dactinomycin; Ethionine; Fluorourac | 1968 |