Page last updated: 2024-10-27

fluorouracil and Eyelid Neoplasms

fluorouracil has been researched along with Eyelid Neoplasms in 14 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Eyelid Neoplasms: Tumors of cancer of the EYELIDS.

Research Excerpts

ExcerptRelevanceReference
"A 55-year-old Asian Indian woman who had recurrent sebaceous gland carcinoma of the left lower eyelid with orbital extension and regional lymph node metastasis was treated with neoadjuvant chemotherapy, using a combination of carboplatin and 5-fluorouracil."3.73Neoadjuvant chemotherapy in the management of sebaceous gland carcinoma of the eyelid with regional lymph node metastasis. ( Burman, S; Honavar, SG; Murthy, R; Naik, MN; Reddy, VA; Vemuganti, GK, 2005)
"25 horses with 27 T2-stage periocular squamous cell carcinomas."2.68Comparison of intratumoral administration of cisplatin versus bleomycin for treatment of periocular squamous cell carcinomas in horses. ( Carlson, G; Madigan, JE; Metzger, L; Pascoe, JR; Théon, AP, 1997)
"A patient with recurrent breast cancer, who was diagnosed with eyelid metastasis as a part of systemic metastases and in whom systemic chemotherapy was markedly effective, is reported."2.39Eyelid metastasis from breast cancer showing marked response to chemotherapy. ( Abe, K; Adachi, I; Kaneko, A; Narabayashi, M; Tokue, Y; Tsuda, H; Watanabe, T; Yin, DF; Zhang, GJ, 1995)
"Patients diagnosed with Chronic Lymphocytic Leukemia (CLL) have an increased risk of developing second primary cancers."1.31Multiple neoplasms: a case report. ( Pigeaud-Klessens, ML; van der Valk, P, 2002)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's2 (14.29)18.2507
2000's4 (28.57)29.6817
2010's5 (35.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lobato-Berezo, A1
Fernández-Figueras, MT1
Campoy, A1
Pujol, RM1
Moya-Horno, I1
Polski, A1
Sibug Saber, M1
Kim, JW1
Berry, JL1
Gogia, A1
Pushker, N1
Sen, S1
Bakhshi, S1
Schulze Schwering, M1
Schwering, MS1
Chagaluka, G1
Molyneux, E1
Sharkawi, E1
Hamedani, M1
Fouladi, M1
Wollina, U1
Hansel, G1
Koch, A1
Köstler, E1
Murthy, R1
Honavar, SG1
Burman, S1
Vemuganti, GK1
Naik, MN1
Reddy, VA1
Xiang, Q1
Xu, XL1
Liu, SZ1
Wang, CY1
Richter, P1
Sarembe, B1
Geissler, U1
Zhang, GJ1
Adachi, I1
Yin, DF1
Narabayashi, M1
Tokue, Y1
Watanabe, T1
Kaneko, A1
Tsuda, H1
Abe, K1
Théon, AP1
Pascoe, JR1
Madigan, JE1
Carlson, G1
Metzger, L1
Pigeaud-Klessens, ML1
van der Valk, P1
de Keizer, RJ1
de Wolff-Rouendaal, D1
van Delft, JL1
Zeligman, I1
Lutzner, MA1
Scott, CI1

Reviews

1 review available for fluorouracil and Eyelid Neoplasms

ArticleYear
Eyelid metastasis from breast cancer showing marked response to chemotherapy.
    Japanese journal of clinical oncology, 1995, Volume: 25, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoma, Lobular

1995

Trials

2 trials available for fluorouracil and Eyelid Neoplasms

ArticleYear
[Clinical effects of the mixture of 5-fluorouracil and triamcinolone acetonide on capillary hemangioma of eyelid].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2006, Volume: 31, Issue:6

    Topics: Eyelid Neoplasms; Female; Fluorouracil; Hemangioma, Capillary; Humans; Male; Treatment Outcome; Tria

2006
Comparison of intratumoral administration of cisplatin versus bleomycin for treatment of periocular squamous cell carcinomas in horses.
    American journal of veterinary research, 1997, Volume: 58, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bleomy

1997

Other Studies

11 other studies available for fluorouracil and Eyelid Neoplasms

ArticleYear
Monocle tumor as tonsillar squamous cell carcinoma metastasis: resolution after chemotherapy treatment.
    International journal of dermatology, 2018, Volume: 57, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Carcinoma, Squamous Cell; Cetuximab;

2018
Extending far and wide: the role of biopsy and staging in the management of ocular surface squamous neoplasia.
    Clinical & experimental ophthalmology, 2019, Volume: 47, Issue:2

    Topics: Aged; Antineoplastic Agents; Biopsy; Carcinoma, Squamous Cell; Conjunctival Neoplasms; Corneal Disea

2019
Avoidance of exenteration in orbital sebaceous gland carcinoma with neoadjuvant chemotherapy.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2013, Volume: 251, Issue:10

    Topics: Adenocarcinoma, Sebaceous; Cisplatin; Eye Evisceration; Eyelid Neoplasms; Fluorouracil; Humans; Male

2013
Treatment of cancer in a child with ocular xeroderma pigmentosa (XP) in Malawi.
    Journal of pediatric hematology/oncology, 2014, Volume: 36, Issue:8

    Topics: Antimetabolites, Antineoplastic; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Child, Preschool;

2014
Eyelid squamous cell carcinoma in situ treated with topical 5-fluorouracil.
    Clinical & experimental ophthalmology, 2011, Volume: 39, Issue:9

    Topics: Administration, Topical; Aged; Antimetabolites, Antineoplastic; Bowen's Disease; Eyelid Neoplasms; F

2011
Oral capecitabine plus subcutaneous interferon alpha in advanced squamous cell carcinoma of the skin.
    Journal of cancer research and clinical oncology, 2005, Volume: 131, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capeci

2005
Neoadjuvant chemotherapy in the management of sebaceous gland carcinoma of the eyelid with regional lymph node metastasis.
    Ophthalmic plastic and reconstructive surgery, 2005, Volume: 21, Issue:4

    Topics: Adenocarcinoma, Sebaceous; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Eyelid Neopl

2005
[Malignant melanoma of the vagina].
    Archiv fur Geschwulstforschung, 1980, Volume: 50, Issue:2

    Topics: Adult; BCG Vaccine; Cyclophosphamide; Drug Therapy, Combination; Eyelid Neoplasms; Female; Fluoroura

1980
Multiple neoplasms: a case report.
    Orbit (Amsterdam, Netherlands), 2002, Volume: 21, Issue:2

    Topics: Aged; Antimetabolites, Antineoplastic; Blepharoplasty; Carcinoma in Situ; Carcinoma, Squamous Cell;

2002
Topical application of 5-fluorouracil in premalignant lesions of cornea, conjunctiva and eyelid.
    Documenta ophthalmologica. Advances in ophthalmology, 1986, Dec-30, Volume: 64, Issue:1

    Topics: Aged; Carcinoma in Situ; Conjunctival Diseases; Corneal Diseases; Drug Administration Schedule; Eyel

1986
Xeroderma pigmentosum.
    Birth defects original article series, 1971, Volume: 7, Issue:8

    Topics: Adult; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Child, Preschool; Eyelid Neoplasms; Female;

1971