fluorouracil has been researched along with Eyelid Diseases in 9 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Eyelid Diseases: Diseases involving the EYELIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 59-year-old man undergoing systemic 5-fluorouracil treatment for metastatic adenocarcinoma of the stomach developed ocular lesions consisting of bilateral conjunctival ulcers and ulcerative blepharitis leading to ankyloblepharon." | 3.67 | Ankyloblepharon associated with systemic 5-fluorouracil treatment. ( Helm, CJ; Insler, MS, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eiseman, AS | 1 |
| Flanagan, JC | 1 |
| Brooks, AB | 1 |
| Mitchell, EP | 1 |
| Pemberton, CH | 1 |
| Salminen, L | 1 |
| Jäntti, V | 1 |
| Grönross, M | 1 |
| Hochart, G | 1 |
| Piette, F | 1 |
| Olver, JM | 1 |
| Rose, GE | 1 |
| Khaw, PT | 1 |
| Collin, JR | 1 |
| Miyamoto, K | 1 |
| Tanaka, T | 1 |
| Isawa, S | 1 |
| Yamashita, T | 1 |
| Matsuda, A | 1 |
| Bergin, DJ | 1 |
| Lapins, NA | 1 |
| Deffer, TA | 1 |
| Kersten, RC | 1 |
| Insler, MS | 1 |
| Helm, CJ | 1 |
| Rosenoff, SH | 1 |
| Wolf, ML | 1 |
| Chabner, BA | 1 |
1 trial available for fluorouracil and Eyelid Diseases
| Article | Year |
|---|---|
Correction of lower eyelid retraction in thyroid eye disease: a randomised controlled trial of retractor tenotomy with adjuvant antimetabolite versus scleral graft.
Topics: Adult; Aged; Antimetabolites; Eyelid Diseases; Female; Fluorouracil; Humans; Male; Middle Aged; Mito | 1998 |
8 other studies available for fluorouracil and Eyelid Diseases
| Article | Year |
|---|---|
Ocular surface, ocular adnexal, and lacrimal complications associated with the use of systemic 5-fluorouracil.
Topics: Adult; Antimetabolites, Antineoplastic; Black or African American; Cohort Studies; Drug Eruptions; E | 2003 |
Blepharospasm associated with tegafur combination chemotherapy.
Topics: Antineoplastic Agents; Blepharospasm; Drug Therapy, Combination; Eyelid Diseases; Female; Fluorourac | 1984 |
[Treatment of a keratoacanthoma of the upper eyelid by intra-lesional injection of fluorouracil].
Topics: Adolescent; Eyelid Diseases; Female; Fluorouracil; Humans; Keratoacanthoma | 1982 |
[Toxicological studies of bleomycin ointment. Irritative effect of bleomycin ointment on eye mucous membrane and skin (author's transl)].
Topics: Administration, Topical; Animals; Bleomycin; Conjunctiva; Conjunctivitis; Cornea; Erythema; Eye; Eye | 1975 |
Intralesional 5-fluorouracil for keratoacanthoma of the eyelid.
Topics: Aged; Aged, 80 and over; Eyelid Diseases; Fluorouracil; Humans; Keratoacanthoma; Male; Middle Aged; | 1986 |
A warning on antimetabolites and cryosurgery in the reconstruction of eyelids. Case report.
Topics: Aged; Antimetabolites, Antineoplastic; Cryosurgery; Eyelid Diseases; Eyelids; Female; Fluorouracil; | 1987 |
Ankyloblepharon associated with systemic 5-fluorouracil treatment.
Topics: Adenocarcinoma; Blepharitis; Eyelid Diseases; Fluorouracil; Humans; Male; Middle Aged; Skin Ulcer; S | 1987 |
Pseudomonas blepharoconjunctivitis: a complication of combination chemotherapy.
Topics: Antineoplastic Agents; Bacitracin; Blepharitis; Bone Marrow; Breast Neoplasms; Carbenicillin; Cephal | 1974 |