fluorouracil has been researched along with Eye Injuries in 5 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Eye Injuries: Damage or trauma inflicted to the eye by external means. The concept includes both surface injuries and intraocular injuries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To observe the effect of the means of subconjunctiva injection with 5-Fluorouracil (5-Fu) and Triamcinolone to treat the membrane on the anterior surface of intraocular lens after traumatic cataract surgery." | 7.73 | [Combined 5-Fu and triamcinolone to treat the membrane on the anterior surface of intraocular lens after the surgery of traumatic cataract]. ( Chen, L; Xu, D; Ye, K, 2005) |
| "To determine the potential of an intravitreal sustained release naproxen and 5-fluorouracil (NA/5-FU) codrug for the treatment of experimental proliferative vitreoretinopathy (PVR) in a model for trauma associated tractional retinal detachment (TRD)." | 7.72 | An intravitreal biodegradable sustained release naproxen and 5-fluorouracil system for the treatment of experimental post-traumatic proliferative vitreoretinopathy. ( Ashton, P; Cardillo, JA; Costa, RA; Farah, ME; Jorge, R; Kuppermann, B; Melo, LA; Mitre, J; Morales, PH, 2004) |
| "To observe the effect of the means of subconjunctiva injection with 5-Fluorouracil (5-Fu) and Triamcinolone to treat the membrane on the anterior surface of intraocular lens after traumatic cataract surgery." | 3.73 | [Combined 5-Fu and triamcinolone to treat the membrane on the anterior surface of intraocular lens after the surgery of traumatic cataract]. ( Chen, L; Xu, D; Ye, K, 2005) |
| "To determine the potential of an intravitreal sustained release naproxen and 5-fluorouracil (NA/5-FU) codrug for the treatment of experimental proliferative vitreoretinopathy (PVR) in a model for trauma associated tractional retinal detachment (TRD)." | 3.72 | An intravitreal biodegradable sustained release naproxen and 5-fluorouracil system for the treatment of experimental post-traumatic proliferative vitreoretinopathy. ( Ashton, P; Cardillo, JA; Costa, RA; Farah, ME; Jorge, R; Kuppermann, B; Melo, LA; Mitre, J; Morales, PH, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cardillo, JA | 1 |
| Farah, ME | 1 |
| Mitre, J | 1 |
| Morales, PH | 1 |
| Costa, RA | 1 |
| Melo, LA | 1 |
| Kuppermann, B | 1 |
| Jorge, R | 1 |
| Ashton, P | 1 |
| Ye, K | 1 |
| Xu, D | 1 |
| Chen, L | 1 |
| Avni, I | 1 |
| Belkin, M | 1 |
| Hercberg, A | 1 |
| Blumenthal, M | 1 |
| Mermoud, A | 1 |
| Salmon, JF | 1 |
| Barron, A | 1 |
| Straker, C | 1 |
| Murray, AD | 1 |
| Lai, MM | 1 |
| Haller, JA | 1 |
5 other studies available for fluorouracil and Eye Injuries
| Article | Year |
|---|---|
An intravitreal biodegradable sustained release naproxen and 5-fluorouracil system for the treatment of experimental post-traumatic proliferative vitreoretinopathy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biodegradation, Environmental; Disease Models, Ani | 2004 |
[Combined 5-Fu and triamcinolone to treat the membrane on the anterior surface of intraocular lens after the surgery of traumatic cataract].
Topics: Administration, Topical; Cataract; Cataract Extraction; Conjunctiva; Drug Therapy, Combination; Eye | 2005 |
Intravitreal 5-fluorouracil in the prevention of post-traumatic vitreous proliferation.
Topics: Animals; Eye Diseases; Eye Injuries; Female; Fluorouracil; Male; Rabbits; Vitreous Body | 1984 |
Surgical management of post-traumatic angle recession glaucoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anterior Chamber; Child; Combined Modality Therapy; Drai | 1993 |
Resolution of epithelial ingrowth in a patient treated with 5-fluorouracil.
Topics: Adult; Anterior Chamber; Antimetabolites; Corneal Diseases; Epithelial Cells; Eye Injuries; Fluorour | 2002 |