Page last updated: 2024-10-27

fluorouracil and Eye Infections, Fungal

fluorouracil has been researched along with Eye Infections, Fungal in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Eye Infections, Fungal: Infection by a variety of fungi, usually through four possible mechanisms: superficial infection producing conjunctivitis, keratitis, or lacrimal obstruction; extension of infection from neighboring structures - skin, paranasal sinuses, nasopharynx; direct introduction during surgery or accidental penetrating trauma; or via the blood or lymphatic routes in patients with underlying mycoses.

Research Excerpts

ExcerptRelevanceReference
"The recurrent Candida infection affected primarily the iris and lens, rather than the retina and choroid."1.31Recurrent endogenous candidal endophthalmitis in a premature infant. ( Calvano, C; Simon, JW; Stern, JH, 2001)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stern, JH1
Calvano, C1
Simon, JW1

Other Studies

1 other study available for fluorouracil and Eye Infections, Fungal

ArticleYear
Recurrent endogenous candidal endophthalmitis in a premature infant.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2001, Volume: 5, Issue:1

    Topics: Amphotericin B; Betaxolol; Candida albicans; Candidiasis; Drug Therapy, Combination; Endophthalmitis

2001