fluorouracil has been researched along with Eye Abnormalities in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Eye Abnormalities: Congenital absence of or defects in structures of the eye; may also be hereditary.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lynch, DW | 1 |
| Schuler, RL | 1 |
| Davis, DG | 1 |
| Hood, RD | 1 |
| Forsthoefel, PF | 1 |
2 other studies available for fluorouracil and Eye Abnormalities
| Article | Year |
|---|---|
Eye abnormality in Drosophila melanogaster exposed to 5-fluorouracil during development.
Topics: Animals; Drosophila melanogaster; Eye Abnormalities; Fluorouracil | 1992 |
The effects on mouse development of interactions of 5-fluorouracil with Strong's luxoid gene and its plus and minus modifiers.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Bone and Bones; Cleft Palate; Embryo, | 1972 |