fluorouracil has been researched along with Exocrine Pancreatic Insufficiency in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Exocrine Pancreatic Insufficiency: A malabsorption condition resulting from greater than 10% reduction in the secretion of pancreatic digestive enzymes (LIPASE; PROTEASES; and AMYLASE) by the EXOCRINE PANCREAS into the DUODENUM. This condition is often associated with CYSTIC FIBROSIS and with chronic PANCREATITIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The study included 127 gastric cancer patients, who underwent preoperative or postoperative chemoradiotherapy." | 1.43 | Radiation-induced injury of the exocrine pancreas after chemoradiotherapy for gastric cancer. ( Maslyk, B; Polanowski, P; Tukiendorf, A; Wydmanski, J, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wydmanski, J | 1 |
| Polanowski, P | 1 |
| Tukiendorf, A | 1 |
| Maslyk, B | 1 |
1 other study available for fluorouracil and Exocrine Pancreatic Insufficiency
| Article | Year |
|---|---|
Radiation-induced injury of the exocrine pancreas after chemoradiotherapy for gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Exocrine Pancreatic | 2016 |