fluorouracil has been researched along with Exfoliation Glaucoma in 7 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the outcomes of trabeculectomy with 5-fluorouracil (5-FU) with or without subconjunctival bevacizumab in the surgical management of pseudoexfoliation glaucoma (PXG)." | 7.91 | Initial trabeculectomy with 5-fluorouracil with or without subconjunctival bevacizumab in the management of pseudoexfoliation glaucoma. ( Çolak, S; Elgin, U; Sen, E; Yılmazbas, P, 2019) |
| "To investigate the outcomes of trabeculectomy with 5-fluorouracil (5-FU) with or without subconjunctival bevacizumab in the surgical management of pseudoexfoliation glaucoma (PXG)." | 3.91 | Initial trabeculectomy with 5-fluorouracil with or without subconjunctival bevacizumab in the management of pseudoexfoliation glaucoma. ( Çolak, S; Elgin, U; Sen, E; Yılmazbas, P, 2019) |
| "Intraocular pressure was 20 mmHg or lower in 94% of 5-FU eyes and in 73% of control eyes (P < 0." | 2.67 | 5-Fluorouracil in initial trabeculectomy. A prospective, randomized, multicenter study. ( Gieser, DK; Goldenfeld, M; Krupin, T; Liebmann, JM; Ritch, R; Rosenberg, LF; Ruderman, JM; Wong, PC, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elgin, U | 1 |
| Sen, E | 1 |
| Çolak, S | 1 |
| Yılmazbas, P | 1 |
| Arnljots, TS | 1 |
| Kasina, R | 1 |
| Bykov, VJN | 1 |
| Economou, MA | 1 |
| Carassa, RG | 1 |
| Bettin, P | 1 |
| Fiori, M | 1 |
| Brancato, R | 1 |
| Goldenfeld, M | 1 |
| Krupin, T | 1 |
| Ruderman, JM | 1 |
| Wong, PC | 1 |
| Rosenberg, LF | 1 |
| Ritch, R | 2 |
| Liebmann, JM | 2 |
| Gieser, DK | 1 |
| Spiegel, D | 1 |
| Sachs, H | 1 |
| Yanes, G | 1 |
| Samuelson, TW | 1 |
| Rothman, RF | 1 |
1 review available for fluorouracil and Exfoliation Glaucoma
| Article | Year |
|---|---|
Management of coincident glaucoma and cataract.
Topics: Cataract; Cataract Extraction; Exfoliation Syndrome; Fluorouracil; Glaucoma; Humans; Lenses, Intraoc | 1995 |
2 trials available for fluorouracil and Exfoliation Glaucoma
| Article | Year |
|---|---|
Viscocanalostomy versus trabeculectomy in white adults affected by open-angle glaucoma: a 2-year randomized, controlled trial.
Topics: Aged; Anterior Eye Segment; Conjunctiva; Exfoliation Syndrome; Female; Fluorouracil; Glaucoma, Open- | 2003 |
5-Fluorouracil in initial trabeculectomy. A prospective, randomized, multicenter study.
Topics: Aged; Aged, 80 and over; Combined Modality Therapy; Exfoliation Syndrome; Female; Fluorouracil; Foll | 1994 |
4 other studies available for fluorouracil and Exfoliation Glaucoma
| Article | Year |
|---|---|
Initial trabeculectomy with 5-fluorouracil with or without subconjunctival bevacizumab in the management of pseudoexfoliation glaucoma.
Topics: Aged; Angiogenesis Inhibitors; Antihypertensive Agents; Bevacizumab; Exfoliation Syndrome; Female; F | 2019 |
Needling With 5-Fluorouracil (5-FU) After XEN Gel Stent Implantation: 6-Month Outcomes.
Topics: Aged; Aged, 80 and over; Exfoliation Syndrome; Female; Fluorouracil; Gels; Glaucoma; Glaucoma Draina | 2018 |
[Single dose intraoperative administration of 5-fluorouracil (5-FU) in trabeculectomy. Long-term results of a pilot study].
Topics: Aged; Antimetabolites; Cell Division; Exfoliation Syndrome; Female; Fluorouracil; Glaucoma, Open-Ang | 1996 |
Noninfectious crystalline keratopathy after postoperative subconjunctival 5-fluorouracil.
Topics: Aged; Antimetabolites; Conjunctiva; Cornea; Corneal Diseases; Diagnosis, Differential; Exfoliation S | 1999 |