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fluorouracil and Esophagotracheal Fistula

fluorouracil has been researched along with Esophagotracheal Fistula in 4 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"A diagnosis of esophageal cancer with subcutaneous abscess was made based on examination and biopsy results."1.31[A patient with esophageal cancer with subcutaneal abscess and esophago-tracheal fistula who survived more than 2 years following treatment by drainage and chemoradiation therapy]. ( Furukawa, J; Katsumoto, Y; Maruyama, K; Maruyama, N; Morimoto, T; Nakaguchi, K; Nakamura, M; Okajima, S; Shingai, T; Sue, F, 2001)
"However, the presence of a tracheoesophageal fistula has historically been considered a relative contraindication to radiation therapy."1.29Irradiation of carcinoma of the esophagus containing a tracheoesophageal fistula. ( Arlington, A; Bohorquez, J, 1993)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Krauss, N1
Wein, A1
Boxberger, F1
Baum, U1
Männlein, G1
Sezer, O1
Hahn, EG1
Benninger, J1
Shitara, K1
Munakata, M1
Ishiguro, A1
Hoshi, Y1
Okada, R1
Tomioka, R1
Mitobe, S1
Sakata, Y1
Ebina, A1
Aoki, M1
Arlington, A1
Bohorquez, J1
Nakamura, M1
Maruyama, K1
Furukawa, J1
Maruyama, N1
Shingai, T1
Katsumoto, Y1
Nakaguchi, K1
Okajima, S1
Sue, F1
Morimoto, T1

Other Studies

4 other studies available for fluorouracil and Esophagotracheal Fistula

ArticleYear
Complete remission with long-term survival in a patient with esophageal carcinoma and a tracheoesophageal fistula after treatment with the AIO regimen and bi-weekly cisplatin.
    Zeitschrift fur Gastroenterologie, 2004, Volume: 42, Issue:8

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease-Free Survi

2004
[A case of advanced esophageal cancer with suspected tracheoesophageal fistula that responded to chemoradiotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administr

2006
Irradiation of carcinoma of the esophagus containing a tracheoesophageal fistula.
    Cancer, 1993, Jun-15, Volume: 71, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali

1993
[A patient with esophageal cancer with subcutaneal abscess and esophago-tracheal fistula who survived more than 2 years following treatment by drainage and chemoradiation therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:11

    Topics: Abscess; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Draina

2001