fluorouracil has been researched along with Esophageal and Gastric Varices in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Esophageal and Gastric Varices: Dilated blood vessels in the ESOPHAGUS or GASTRIC FUNDUS that shunt blood from the portal circulation (PORTAL SYSTEM) to the systemic venous circulation. Often they are observed in individuals with portal hypertension (HYPERTENSION, PORTAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, esophagogastric varices are a poorly recognized outcome of oxaliplatin-based chemotherapy." | 1.48 | Esophagogastric varices were diagnosed in a non-cirrhotic liver case during long-term follow-up after oxaliplatin-based chemotherapy. ( Ehira, T; Hattori, N; Ikeda, H; Itoh, F; Katayama, M; Koizumi, S; Matsumoto, N; Matsunaga, K; Matsuo, Y; Mizukami, T; Nakahara, K; Nakajima, TE; Nakano, H; Okuse, C; Otsubo, T; Sato, Y; Shigefuku, R; Suzuki, M; Suzuki, T; Tsuda, T; Watanabe, T; Yasuda, H, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shigefuku, R | 1 |
| Watanabe, T | 1 |
| Mizukami, T | 1 |
| Matsunaga, K | 1 |
| Hattori, N | 1 |
| Ehira, T | 1 |
| Suzuki, T | 1 |
| Nakano, H | 1 |
| Sato, Y | 1 |
| Matsuo, Y | 1 |
| Nakahara, K | 1 |
| Ikeda, H | 1 |
| Matsumoto, N | 1 |
| Tsuda, T | 1 |
| Katayama, M | 1 |
| Koizumi, S | 1 |
| Okuse, C | 1 |
| Suzuki, M | 1 |
| Otsubo, T | 1 |
| Nakajima, TE | 1 |
| Yasuda, H | 1 |
| Itoh, F | 1 |
| Lawal, TO | 1 |
| Farris, AB | 1 |
| El-Rayes, BF | 1 |
| Subramanian, RM | 1 |
| Kim, HS | 1 |
| Sugimoto, K | 1 |
| Shiraki, K | 1 |
| Yamanaka, Y | 1 |
| Yamamoto, N | 1 |
| Murata, K | 1 |
| Nakano, T | 1 |
| Sacks, H | 1 |
| Chalmers, TC | 1 |
| Smith, H | 1 |
4 other studies available for fluorouracil and Esophageal and Gastric Varices
| Article | Year |
|---|---|
Esophagogastric varices were diagnosed in a non-cirrhotic liver case during long-term follow-up after oxaliplatin-based chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Eso | 2018 |
Oxaliplatin-induced hepatoportal sclerosis, portal hypertension, and variceal bleeding successfully treated with transjugular intrahepatic portosystemic shunt.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colo | 2012 |
Images of interest. Hepatobiliary and pancreatic: Tumor thrombi in esophageal varices.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Endoscopy; Eso | 2005 |
Randomized versus historical controls for clinical trials.
Topics: Abortion, Habitual; Anticoagulants; BCG Vaccine; Clinical Trials as Topic; Colonic Neoplasms; Corona | 1982 |