Page last updated: 2024-10-27

fluorouracil and Esophageal Reflux

fluorouracil has been researched along with Esophageal Reflux in 4 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"Obesity is a risk factor for the development of esophageal malignancy."1.37Esophageal adenocarcinoma after laparoscopic gastric band placement for obesity. ( Mathew, J; Odell, JA; Stauffer, JA, 2011)
"Columnar-lined or Barrett's esophagus is a premalignant condition."1.29Is chemotherapy associated with development of Barrett's esophagus? ( Kleibeuker, JH; Peters, FT; Sleijfer, DT; van Imhoff, GW, 1993)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, B1
Ji, SQ1
Hua, YW1
Liu, YQ1
Stauffer, JA1
Mathew, J1
Odell, JA1
Peters, FT1
Sleijfer, DT1
van Imhoff, GW1
Kleibeuker, JH1
Peracchia, A1
Bonavina, L1
Via, A1
Incarbone, R1

Other Studies

4 other studies available for fluorouracil and Esophageal Reflux

ArticleYear
[Application of jejunal interposition after radical proximal gastrectomy].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2013, Volume: 35, Issue:7

    Topics: Aged; Anastomosis, Surgical; Antineoplastic Combined Chemotherapy Protocols; C-Reactive Protein; Che

2013
Esophageal adenocarcinoma after laparoscopic gastric band placement for obesity.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2011, Volume: 24, Issue:1

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Bariatric Surgery; Deglutition

2011
Is chemotherapy associated with development of Barrett's esophagus?
    Digestive diseases and sciences, 1993, Volume: 38, Issue:5

    Topics: Adult; Antineoplastic Agents; Barrett Esophagus; Breast Neoplasms; Cisplatin; Drug Therapy, Combinat

1993
Current trends in the surgical treatment of esophageal and cardia adenocarcinoma.
    Journal of experimental & clinical cancer research : CR, 1999, Volume: 18, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Barrett Esophagus; Cardia; Chemother

1999