fluorouracil has been researched along with Esophageal Achalasia in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Esophageal Achalasia: A motility disorder of the ESOPHAGUS in which the LOWER ESOPHAGEAL SPHINCTER (near the CARDIA) fails to relax resulting in functional obstruction of the esophagus, and DYSPHAGIA. Achalasia is characterized by a grossly contorted and dilated esophagus (megaesophagus).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Achalasia is a recognized risk factor for esophageal SCC." | 1.43 | [A Case of Squamous Cell Carcinoma of the Esophagus with Achalasia -- Conversion from Chemoradiotherapy to Surgery]. ( Hanaki, K; Higashide, S; Kanda, Y; Mise, M; Morimoto, T; Nio, M; Noda, H; Yata, Y; Yonenaga, Y, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morimoto, T | 1 |
| Yata, Y | 1 |
| Nio, M | 1 |
| Yonenaga, Y | 1 |
| Hanaki, K | 1 |
| Mise, M | 1 |
| Higashide, S | 1 |
| Kanda, Y | 1 |
| Noda, H | 1 |
| Chun, CL | 1 |
| Eisenstat, S | 1 |
| Dormady, S | 1 |
| Lombard, C | 1 |
| Triadafilopoulos, G | 1 |
| JUSTIN-BESANCON, L | 1 |
| GRIVAUX, M | 1 |
| CORNET, A | 1 |
| TOURNEUR, R | 1 |
| GUERRE, J | 1 |
3 other studies available for fluorouracil and Esophageal Achalasia
| Article | Year |
|---|---|
[A Case of Squamous Cell Carcinoma of the Esophagus with Achalasia -- Conversion from Chemoradiotherapy to Surgery].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; C | 2016 |
Esophageal adenocarcinoma presenting as pseudo-achalasia in a patient with juvenile polyposis syndrome: an enemy out of the blue.
Topics: Adenocarcinoma; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antiemetics; Antin | 2011 |
[RESEARCH ON CERTAIN DIGESTIVE DYSKINESIAS AND FUNCTIONAL DISORDERS].
Topics: Antiemetics; Apomorphine; Cobalt Isotopes; Cyclophosphamide; Digitalis Glycosides; Dyskinesias; Dysp | 1964 |