Page last updated: 2024-10-27

fluorouracil and Erythrocytosis

fluorouracil has been researched along with Erythrocytosis in 3 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"A case of hepatocellular carcinoma associated with erythrocytosis is described."1.26Hepatocellular carcinoma associated with erythrocytosis. A nine year survival after successful chemotherapy and left lateral hepatectomy. ( Arima, M; Hattori, N; Kimura, K; Okazaki, N; Ozaki, H, 1979)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Okazaki, N1
Ozaki, H1
Arima, M1
Hattori, N1
Kimura, K1
Scott, D1
Theologides, A1
Kretchmar, AL1
McDonald, TP1
Lange, RD1

Other Studies

3 other studies available for fluorouracil and Erythrocytosis

ArticleYear
Hepatocellular carcinoma associated with erythrocytosis. A nine year survival after successful chemotherapy and left lateral hepatectomy.
    Acta hepato-gastroenterologica, 1979, Volume: 26, Issue:3

    Topics: Carcinoma, Hepatocellular; Erythropoietin; Fluorouracil; Hepatectomy; Humans; Liver Neoplasms; Male;

1979
Hepatoma, erythrocytosis and increased serum erythropoietin developing in long-standing hemochromatosis.
    The American journal of gastroenterology, 1974, Volume: 61, Issue:3

    Topics: Aged; Animals; Biopsy, Needle; Carcinoma, Hepatocellular; Chronic Disease; Erythropoietin; Female; F

1974
Mode of action of erythropoietin in polycythemic mice. I. Response in mice treated with 5-fluorouracil.
    The Journal of laboratory and clinical medicine, 1970, Volume: 75, Issue:1

    Topics: Animals; Erythrocytes; Erythropoietin; Female; Fluorouracil; Iron; Iron Isotopes; Mitosis; Polycythe

1970