fluorouracil has been researched along with Epidural Neoplasm, Malignant in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (50.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Bagatzounis, A | 1 |
Erakleous, E | 1 |
Michaelides, I | 1 |
Boogerd, W | 1 |
van der Sande, JJ | 1 |
Kröger, R | 1 |
Bruning, PF | 1 |
Somers, R | 1 |
2 other studies available for fluorouracil and Epidural Neoplasm, Malignant
Article | Year |
---|---|
Epidural metastasis in nasopharyngeal carcinoma.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma; Cervical Vertebrae; Cispla | 2003 |
Effective systemic therapy for spinal epidural metastases from breast carcinoma.
Topics: Adult; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cy | 1989 |