fluorouracil has been researched along with Enterocolitis in 7 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Enterocolitis: Inflammation of the MUCOSA of both the SMALL INTESTINE and the LARGE INTESTINE. Etiology includes ISCHEMIA, infections, allergic, and immune responses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors report a patient with colorectal carcinoma who developed neutropenic enterocolitis after treatment with 5-fluorouracil and leucovorin." | 7.69 | Neutropenic enterocolitis in a patient with colorectal carcinoma: unusual course after treatment with 5-fluorouracil and leucovorin--a case report. ( Blumgart, L; Kemeny, NE; Kronawitter, U, 1997) |
| "Capecitabine is an oral 5-fluorouracil prodrug with antimetabolite activity commonly used in advanced colorectal and breast cancer." | 7.01 | Capecitabine-associated enterocolitis: Narrative literature review of a rare adverse event and a case presentation. ( Gomatou, G; Kanellis, G; Kotteas, EA; Lagou, S; Rapti, VE; Syrigos, NK; Trontzas, IP, 2023) |
| "Capecitabine is a widely-used antineoplastic drug, a prodrug to 5-fluorouracil which commonly induces gastrointestinal toxicity." | 5.72 | Capecitabine-induced enterocolitis: a case report and pharmacogenetic profile. ( Chen, J; Liu, J; Shao, T; Shou, L; Shu, Q; Zhang, Y, 2022) |
| "The authors report a patient with colorectal carcinoma who developed neutropenic enterocolitis after treatment with 5-fluorouracil and leucovorin." | 3.69 | Neutropenic enterocolitis in a patient with colorectal carcinoma: unusual course after treatment with 5-fluorouracil and leucovorin--a case report. ( Blumgart, L; Kemeny, NE; Kronawitter, U, 1997) |
| "Capecitabine is an oral 5-fluorouracil prodrug with antimetabolite activity commonly used in advanced colorectal and breast cancer." | 3.01 | Capecitabine-associated enterocolitis: Narrative literature review of a rare adverse event and a case presentation. ( Gomatou, G; Kanellis, G; Kotteas, EA; Lagou, S; Rapti, VE; Syrigos, NK; Trontzas, IP, 2023) |
| "Capecitabine is a widely-used antineoplastic drug, a prodrug to 5-fluorouracil which commonly induces gastrointestinal toxicity." | 1.72 | Capecitabine-induced enterocolitis: a case report and pharmacogenetic profile. ( Chen, J; Liu, J; Shao, T; Shou, L; Shu, Q; Zhang, Y, 2022) |
| "The mechanism of formation of pseudomembranous colitis, the causative agents and method of diagnosis and treatment were discussed." | 1.28 | [Colitis due to chemotherapeutic agent]. ( Yang, XY, 1990) |
| "Neutropenic enterocolitis is a recognized complication of immunosuppression or chemotherapy for leukemia." | 1.28 | Neutropenic enterocolitis. A new complication of head and neck cancer chemotherapy. ( de Vries, EJ; Johnson, JT; Petruzzelli, GJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Trontzas, IP | 1 |
| Rapti, VE | 1 |
| Syrigos, NK | 1 |
| Gomatou, G | 1 |
| Lagou, S | 1 |
| Kanellis, G | 1 |
| Kotteas, EA | 1 |
| Shao, T | 3 |
| Zhang, Y | 3 |
| Liu, J | 3 |
| Chen, J | 3 |
| Shu, Q | 3 |
| Shou, L | 3 |
| Gordon, VL | 1 |
| Harding, GA | 1 |
| Czaykowski, P | 1 |
| Lin, HY | 1 |
| Jen, YM | 1 |
| Kronawitter, U | 1 |
| Kemeny, NE | 1 |
| Blumgart, L | 1 |
| Yang, XY | 1 |
| Petruzzelli, GJ | 1 |
| Johnson, JT | 1 |
| de Vries, EJ | 1 |
1 review available for fluorouracil and Enterocolitis
| Article | Year |
|---|---|
Capecitabine-associated enterocolitis: Narrative literature review of a rare adverse event and a case presentation.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Enteritis; Enterocolitis; Fluorouracil | 2023 |
6 other studies available for fluorouracil and Enterocolitis
| Article | Year |
|---|---|
Capecitabine-induced enterocolitis: a case report and pharmacogenetic profile.
Topics: Capecitabine; Diarrhea; Enterocolitis; Fluorouracil; Humans; Pharmacogenetics | 2022 |
Capecitabine-induced enterocolitis: a case report and pharmacogenetic profile.
Topics: Capecitabine; Diarrhea; Enterocolitis; Fluorouracil; Humans; Pharmacogenetics | 2022 |
Capecitabine-induced enterocolitis: a case report and pharmacogenetic profile.
Topics: Capecitabine; Diarrhea; Enterocolitis; Fluorouracil; Humans; Pharmacogenetics | 2022 |
Capecitabine-induced enterocolitis: a case report and pharmacogenetic profile.
Topics: Capecitabine; Diarrhea; Enterocolitis; Fluorouracil; Humans; Pharmacogenetics | 2022 |
Capecitabine-induced enterocolitis: a case report and pharmacogenetic profile.
Topics: Capecitabine; Diarrhea; Enterocolitis; Fluorouracil; Humans; Pharmacogenetics | 2022 |
Capecitabine-induced enterocolitis: a case report and pharmacogenetic profile.
Topics: Capecitabine; Diarrhea; Enterocolitis; Fluorouracil; Humans; Pharmacogenetics | 2022 |
Capecitabine-induced enterocolitis: a case report and pharmacogenetic profile.
Topics: Capecitabine; Diarrhea; Enterocolitis; Fluorouracil; Humans; Pharmacogenetics | 2022 |
Capecitabine-induced enterocolitis: a case report and pharmacogenetic profile.
Topics: Capecitabine; Diarrhea; Enterocolitis; Fluorouracil; Humans; Pharmacogenetics | 2022 |
Capecitabine-induced enterocolitis: a case report and pharmacogenetic profile.
Topics: Capecitabine; Diarrhea; Enterocolitis; Fluorouracil; Humans; Pharmacogenetics | 2022 |
Capecitabine-induced, nonneutropenic enterocolitis.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Capecitabine; Cecal Neoplasms; Chemotherapy, Adjuva | 2011 |
Images in clinical medicine. Diffuse chemoradiotherapy-related enterocolitis.
Topics: Adenocarcinoma; Aged, 80 and over; Antimetabolites, Antineoplastic; Colon; Combined Modality Therapy | 2007 |
Neutropenic enterocolitis in a patient with colorectal carcinoma: unusual course after treatment with 5-fluorouracil and leucovorin--a case report.
Topics: Antidotes; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Enterocolitis; Fluorouracil; Human | 1997 |
[Colitis due to chemotherapeutic agent].
Topics: Adult; Antineoplastic Agents; Enterocolitis; Enterocolitis, Pseudomembranous; Female; Fluorouracil; | 1990 |
Neutropenic enterocolitis. A new complication of head and neck cancer chemotherapy.
Topics: Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin | 1990 |