fluorouracil has been researched along with Enterocolitis, Pseudomembranous in 7 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Enterocolitis, Pseudomembranous: An acute inflammation of the INTESTINAL MUCOSA that is characterized by the presence of pseudomembranes or plaques in the SMALL INTESTINE (pseudomembranous enteritis) and the LARGE INTESTINE (pseudomembranous colitis). It is commonly associated with antibiotic therapy and CLOSTRIDIUM DIFFICILE colonization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pseudomembranous colitis is frequently associated with antibiotics and more rarely with chemotherapeutic agents such as 5-fluorouracil." | 1.33 | Pseudomembranous colitis associated with chemotherapy with 5-fluorouracil. ( Aranda Aguilar, E; de la Haba Rodríguez, JR; Gómez España, MA; Méndez Vidal, MJ; Morales Chamorro, R; Rubio Pérez, MJ; Serrano Blanch, R, 2005) |
| "The mechanism of formation of pseudomembranous colitis, the causative agents and method of diagnosis and treatment were discussed." | 1.28 | [Colitis due to chemotherapeutic agent]. ( Yang, XY, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morales Chamorro, R | 1 |
| Serrano Blanch, R | 1 |
| Méndez Vidal, MJ | 1 |
| Gómez España, MA | 1 |
| Rubio Pérez, MJ | 1 |
| de la Haba Rodríguez, JR | 1 |
| Aranda Aguilar, E | 1 |
| Cheon, SH | 1 |
| Kim, KH | 1 |
| Sung, HC | 1 |
| Wu, PC | 1 |
| Wang, YB | 1 |
| Takao, T | 1 |
| Nishida, M | 1 |
| Maeda, Y | 1 |
| Takao, K | 1 |
| Oka, M | 1 |
| Iveson, TJ | 1 |
| Chan, A | 1 |
| Yang, XY | 1 |
| Maeta, M | 1 |
| Mizusawa, K | 1 |
| Koga, S | 1 |
7 other studies available for fluorouracil and Enterocolitis, Pseudomembranous
| Article | Year |
|---|---|
Pseudomembranous colitis associated with chemotherapy with 5-fluorouracil.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Clostridioides difficile; Dihydropyrimidine Dehydro | 2005 |
[Pseudomembranous colitis after 5-fluorouracil chemotherapy in rectal cancer patient].
Topics: Antimetabolites, Antineoplastic; Colon; Colonoscopy; Enterocolitis, Pseudomembranous; Fluorouracil; | 2005 |
Re-evaluation of 5-fluorouracil as a single agent for gestational malignant trophoblastic neoplasms.
Topics: Enterocolitis, Pseudomembranous; Female; Fluorouracil; Follow-Up Studies; Humans; Liver; Pregnancy; | 1984 |
[The study of continuous infusion chemotherapy with low-dose cisplatin and 5-fluorouracil for patients with primary liver cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cholangiocarcinoma; | 1997 |
Pseudomembranous colitis complicating chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Enterocolitis, P | 1992 |
[Colitis due to chemotherapeutic agent].
Topics: Adult; Antineoplastic Agents; Enterocolitis; Enterocolitis, Pseudomembranous; Female; Fluorouracil; | 1990 |
Induction of diffuse necrotizing enterocolitis by anticancer chemotherapy.
Topics: Cisplatin; Enterocolitis, Pseudomembranous; Fluorouracil; Humans; Infusions, Intra-Arterial; Intesti | 1987 |